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Quality of meta-analyses for randomized trials in the field of hypertension: a systematic review.

J Hypertens

December 2016

aUCONN School of Medicine, Bridgeport, Connecticut bUniversity of Colorado Hospital, Aurora, Colorado cRutgers Robert Wood Johnson Medical School, Brunswick, New Jersey dPacific Northwest University of Health Sciences, Yakima, Washington eJohnson & Johnson, Titusville, New Jersey, USA.

Objectives: Doubling on average every 6 years, hypertension-related meta-analyses are now published twice weekly and are often considered the highest level of evidence for clinical practice. However, some hypertension specialists and guideline authors view meta-analyses with skepticism. This article evaluates the quality of hypertension-related meta-analyses of clinical trials.

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