8 results match your criteria: "New Jersey Medical School Newark NJ USA.[Affiliation]"

Article Synopsis
  • Normalization of echocardiographic measurements based on body surface area can misclassify patients with obesity or sarcopenia, highlighting the need for better alternative normalization methods.
  • A study involving 3032 individuals assessed echocardiographic parameters, focusing on a subgroup of 608 without cardiopulmonary diseases to derive normative values based on various body size indexation methods.
  • The findings indicate that body surface area and height provided more consistent results across different racial and ethnic groups, with height showing the least variability between sexes.
View Article and Find Full Text PDF
Article Synopsis
  • The North Africa and Middle East (NAME) region has one of the highest burdens of ischemic heart disease (IHD) globally, with significant health impacts reported between 1990 and 2019.
  • In 2019, IHD caused 0.8 million deaths and 18 million disability-adjusted life years (DALYs) lost, demonstrating a 33.3% decrease in the age-standardized DALY rate since 1990, mainly due to reduced years of life lost.
  • Despite improvements, premature deaths from IHD in NAME were higher than global averages, indicating that it remains the leading cause of death and health loss in the region.
View Article and Find Full Text PDF

Background: Cancer therapy-related cardiac dysfunction (CTRCD) is an important treatment-limiting toxicity for patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer that adversely affects cancer and cardiovascular outcomes. Easy-to-use tools that incorporate readily accessible clinical variables for individual estimation of CTRCD risk are needed.

Methods And Results: From 2004 to 2013, 1440 patients with stage I to III HER2-positive breast cancer treated with trastuzumab-based therapy were identified.

View Article and Find Full Text PDF

Vitamin D: A Critical Regulator of Intestinal Physiology.

JBMR Plus

December 2021

Department of Microbiology, Biochemistry and Molecular Genetics Rutgers, the State University of New Jersey, New Jersey Medical School Newark NJ USA.

Calcium is required for the functioning of numerous biological processes and is essential for skeletal health. The major source of new calcium is from the diet. The central role of vitamin D in the maintenance of calcium homeostasis is to increase the absorption of ingested calcium from the intestine.

View Article and Find Full Text PDF

Objectives: The objective was to bridge the relative educational gap for newly matched emergency medicine preinterns between Match Day and the start of internship by implementing an Accreditation Council for Graduate Medical Education Milestone (ACGME)-based virtual case curriculum over the social media platform Slack.

Methods: We designed a Milestone-based curriculum of 10 emergency department clinical cases and used Slack to implement it. An instructor was appointed for each participating institution to lead the discussion and encourage collaboration among preinterns.

View Article and Find Full Text PDF

Persons with neurologically motor-complete spinal cord injury (SCI) have a marked loss of bone mineral density (BMD) of the long bones of the lower extremities, predisposing them to fragility fractures, especially at the knee. Denosumab, a commercially available human monoclonal IgG antibody to receptor activator of nuclear factor-κB ligand (RANKL), may provide an immunopharmacological solution to the rapid progressive deterioration of sublesional bone after SCI. Twenty-six SCI participants with subacute motor-complete SCI were randomized to receive either denosumab (60 mg) or placebo at baseline (BL), 6, and 12 months.

View Article and Find Full Text PDF