Gravity-Driven Ultrahigh-Speed Electrospinning for the Production of Ethyl Cellulose Fibers with Tunable Porosity for Oil Absorption.

Ethyl cellulose (EC) is a biocompatible, renewable, and recyclable material with diverse sources, making it an attractive candidate for industrial applications. Electrospinning has gained significant attention for the production of EC fibers. However, conventional electrospinning methods face challenges such as bead formation, low yield, and the absence of porous internal structures, limiting both the functional performance and scalability.

Gratitude for Bystander Action Varies by Peer Intervention and Social Norms.

Gratitude is associated with increased social integration, which may counter the loneliness stemming from repeated peer victimization. The gratitude youth feel after different types of bystander action may depend on which behaviors are most congruent with personal beliefs. Face and honor cultures provide social norms for expectations and interpretations of behavior, including how to act during and after interpersonal conflict.

Metastatic Anaplastic Thyroid Carcinoma to the Right Ventricle.

Anaplastic thyroid carcinoma (ATC) is a rare, yet extremely aggressive form of thyroid cancer characterized by rapid growth and early metastasis to distant sites. Cardiac involvement is very uncommon and the presentation of cardiac metastasis in ATC can vary widely, highlighting the importance of early clinical recognition. We describe an extremely rare case of metastatic ATC that spread to the right ventricle.

Migration of Hepatocellular Carcinoma Into the Right Atrium.

A 40-year-old man with a medical history of hepatitis B presented with abdominal distention and leg swelling. A computed tomography scan of the abdomen revealed cirrhosis and a large mass extending from the liver into the inferior vena cava and extending into the right atrium. A transthoracic echocardiogram revealed a large right atrial mass extending from the inferior vena cava with possible attachment to the interatrial septum.

Multimodality Approach to a Neonate With a Pericardial Mass and a Hemorrhagic Pericardial Effusion.

A 7-week-old infant with a 1-week history of a SARS-CoV2 respiratory infection presented with tachypnea. Cardiomegaly was noted on chest roentgenogram. Echocardiogram showed a large pericardial effusion, with tamponade physiology and a large pericardial mass.

Effects of a Serotonin Receptor Peptide on Behavioral Pattern Separation in Sham- vs. Mild Traumatic Brain Injured Rats.

Aims: Behavioral pattern separation is a hippocampal-dependent component of episodic memory and a sensitive marker of early cognitive decline. Here we tested whether mild traumatic injury causes loss of pattern separation in the rat and for its prevention by a novel neuroprotective peptide fragment of the human serotonin 2A receptor (SN..

Bibliometric analysis of trends in dental management of the children with Autism Spectrum Disorder (ASD).

This study aimed to present a complete overview of the trends, difficulties, and improvements in dental treatment for children diagnosed with autism spectrum disorder through rigorous bibliometric analysis. The dimensional database field was chosen to enable the inclusion and recall of the greatest number of relevant entries. All peer-reviewed international journals published between 2004 and 2023 were included in this study.

A phase I study of MLN4924 and belinostat in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome.

Purpose: Relapsed and/or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome continue to have a poor prognosis with limited treatment options despite advancements in rational combination and targeted therapies. Belinostat (an HDAC inhibitor) and Pevonedistat (a NEDD8 inhibitor) have each been independently studied in hematologic malignancies and have tolerable safety profiles with limited single-agent activity. Preclinical studies in AML cell lines and primary AML cells show the combination to be highly synergistic, particularly in high-risk phenotypes such as p53 mutant and FLT-3-ITD positive cells.

Global collaborations to change the paradigm of oral health education and care: 2024 ADEA Annual Session Chair of the Board Symposium, Proceedings.

The 2024 ADEA Annual Session Chair of the Board Symposium titled, Global Collaborations to Change the Paradigm in Oral Health Education and Care, aimed to highlight innovative global education models in oral health. The symposium sought to identify and explore opportunities for collaboration with international partners to ensure sustainable healthcare education to improve the oral health workforce. Additionally, it focused on discovering and adapting innovative solutions and best practices to enhance access to oral health services worldwide.

Risk Profile and Prognostic Implications of Premature Advanced Coronary Atherosclerotic Disease Among Young to Early Middle-aged Adults: The Coronary Artery Calcium Consortium.

Introduction: Premature advanced subclinical coronary atherosclerosis among young adults is an under-recognized and unique disease phenotype that has not been well characterized.

Methods: We used data from 44,047 participants with no prior CVD history (59.8% male) from the Coronary Artery Calcium (CAC) Consortium.

Distinct molecular and clinical features of specific variants of KRAS codon 12 in pancreatic adenocarcinoma.

PURPOSE Oncogenic mutations in KRAS have been identified in > 85% of pancreatic ductal adenocarcinoma (PDAC) cases. G12D, G12V, and G12R are the most frequent variants. Using large clinical and genomic databases, this study characterizes prognostic and molecular differences between KRAS variants, focusing on KRAS G12D and G12R.

Generative Artificial Intelligence Use in Healthcare: Opportunities for Clinical Excellence and Administrative Efficiency.

Generative Artificial Intelligence (Gen AI) has transformative potential in healthcare to enhance patient care, personalize treatment options, train healthcare professionals, and advance medical research. This paper examines various clinical and non-clinical applications of Gen AI. In clinical settings, Gen AI supports the creation of customized treatment plans, generation of synthetic data, analysis of medical images, nursing workflow management, risk prediction, pandemic preparedness, and population health management.

An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cord.

Peripheral nerve injury (PNI)-induced neuropathic pain (NP) is a severe disease with high prevalence in clinics. Gene reprogramming and tissue remodeling in the dorsal root ganglia (DRG) and spinal cord (SC) drive the development and maintenance of neuropathic pain (NP). However, our understanding of the NP-associated spatial molecular processing landscape of SC and the non-synaptic interactions between DRG neurons and SC cells remains limited.

Resilience in Newly Hired Nursing Faculty: Practical Evidence of a Complex Construct.

Background: Resilience plays a role in workforce retention and has been linked to job satisfaction, quality of life, and organizational commitment in nursing faculty. Research on the nature of faculty resilience, however, remains sparse.

Purpose: The purpose of this study was to contribute to the understanding of nurse faculty resilience by describing examples of specific ways that a group of newly hired nursing faculty enacted resilience during their first few years on the job.

Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial.

Aphasia, a communication disorder caused primarily by left-hemisphere stroke, affects millions of individuals worldwide, with up to 70% experiencing significant reading impairments. These deficits negatively impact independence and quality of life, highlighting the need for effective treatments that target the cognitive and neural processes essential to reading recovery. This Randomized Clinical Trial (RCT) aims to test the efficacy of a combined intervention incorporating aerobic exercise training (AET) and phono-motor treatment (PMT) to enhance reading recovery in individuals with post-stroke aphasia.

A co-produced mixed methods protocol: Exploring perceptions of oral health care and quality of life in people with mental health conditions.

This planned mixed methods protocol is designed to explore oral health care for individuals living with serious mental health conditions (SMHC). It was co-produced by academics, people with lived experience of mental health conditions, and oral and mental health clinicians. The study seeks to explore oral health quality of life predictors and oral health care experiences of people diagnosed with serious mental health conditions (e.

Psychological distress in adolescence and later economic and health outcomes in the United States population: A retrospective and modeling study.

Background: Federal policy impact analyses in the United States do not incorporate the potential economic benefits of adolescent mental health policies. Understanding the extent to which economic benefits may offset policy costs would support more effective policymaking. This study estimates the relationship between adolescent psychological distress and later health and economic outcomes and uses these estimates to determine the potential economic effects of a hypothetical policy.

Utilization of Total Knee Arthroplasty in the United States by Settlement Type: Is There Equity of Access?

Introduction: Total knee arthroplasty (TKA) is one of the most commonly performed orthopaedic surgeries in the United States, yet little information exists regarding its utilization in different settlement types. This study aimed to determine the number of TKA-performing surgeons by settlement type and assess trends in the volume of TKAs in urban, micropolitan, small town, and rural settings.

Methods: Using the Medicare Provider Utilization and Payment Data: Physician and Other Practitioners database, the number of orthopaedic surgeons performing primary and revision TKAs from 2013 to 2020 was determined.

Hunger Strikes After Restricted Housing Reform.

Hunger strikes are a common occurrence in carceral settings accompanied by serious health risks and intensive health care utilization. A 2017 study on hunger strikes within the New Jersey Department of Corrections found these events most often occurred in a disciplinary setting. We undertook this study after a new state law, the Isolated Confinement Restriction Act (ICRA), improved conditions of confinement in part by reducing the utilization, nature, and duration of disciplinary housing.

Decision model to evaluate the cost of clinical events associated with switching from Apixaban to Rivaroxaban among patients with non-valvular atrial fibrillation in the United States and Germany.

Aims: Direct-acting oral anticoagulants (DOACs) have emerged as the preferred treatment for nonvalvular atrial fibrillation (NVAF). However, evidence concerning the economic outcomes of DOAC switching remains limited. This study aimed to assess the economic outcomes of DOAC switching in the US and Germany, two countries with a high AF prevalence and DOAC utilization.

Probing the Photochemical Formation of Hydroxyl Radical from Dissolved Organic Matter: Insights into the HO-Dependent Pathway.

This study quantifies the contribution of the HO-dependent pathway to hydroxyl radical (OH) production from the photolysis of dissolved organic matter (DOM). OH formation rates were cross-validated using benzoate and terephthalate as probe compounds for diverse DOM sources (reference isolates and whole waters). Catalase addition revealed that the HO-dependent pathway accounts for 10-20% of the total OH production in DOM isolate materials, but no significant correlation was observed between ambient iron (Fe) concentrations and HO-dependent OH formation.

Physicochemically Cross-linked Injectable Hydrogel: an Adhesive Skin Substitute for Burned Wound Therapy.

Burns carry a large surface area, varying in shapes and depths, and an elevated risk of infection. Regardless of the underlying etiology, burns pose significant medical challenges and a high mortality rate. Given the limitations of current therapies, tissue-engineering-based treatments for burns are inevitable.