363 results match your criteria: "Nevus Sebaceus"

Article Synopsis
  • Syringocystadenocarcinoma papilliferum (SCACP) is a rare and aggressive cancer originating from skin appendage glands, often linked to previous skin conditions like syringocystadenoma papilliferum or nevus sebaceus.
  • A systematic review analyzed 78 case studies from 1980 to 2024, focusing on clinical features, diagnosis, treatments, and outcomes of SCACP, which commonly affects older adults and presents as ulcerated nodules on the scalp.
  • The study emphasizes the importance of surgical treatment, particularly Mohs micrographic surgery, and suggests more research into standardized treatment protocols and targeted therapies to better improve patient outcomes and understanding of its relationships with other skin conditions.
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In situ baso-squamous carcinoma secondary to nevus sebaceus.

Asian J Surg

August 2024

Hospital for Skin Diseases, Shandong First Medical University, China; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, China. Electronic address:

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Article Synopsis
  • * It has been linked to the development of certain secondary tumors, primarily from follicular germ cells.
  • * The authors present three cases where individuals had both a melanocytic nevus and nevus sebaceus to illustrate this uncommon occurrence.
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Article Synopsis
  • * Primary cutaneous apocrine carcinoma (PCAC) is a rare cancer usually found in older adults, presenting as a dermal tumor with specific histological features.
  • * The occurrence of PCAC developing from nevus sebaceus is extremely rare, with very few documented cases, and this report highlights an unusual instance of both PCAC and another type of tumor within nevus sebaceus on the scalp.
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Nevus Sebaceus With Novel HRAS Sequence Variant Mutation Misdiagnosed as Alopecia Areata.

Cutis

May 2023

Dr. Fernandes is from the San Antonio Uniformed Services Health Education Consortium, Lackland Air Force Base, Texas. Dr. Sang is from US Naval Hospital Yokosuka, Japan. Dr. Sperling is from Walter Reed National Military Medical Center, Bethesda, Maryland. Dr. Sperling also is from the Uniformed Services University of the Health Sciences, Bethesda.

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Introduction: Phacomatosis pigmentokeratotica (PPK), an epidermal nevus syndrome, is characterized by the coexistence of nevus spilus and nevus sebaceus. Within the nevus spilus, an extensive range of atypical nevi of different morphologies may manifest. Pigmented lesions may fulfill the ABCDE criteria for melanoma, which may prompt a physician to perform a full-thickness biopsy.

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Context.—: Syringocystadenocarcinoma papilliferum (SCACP) is a rare adnexal carcinoma and the malignant counterpart of syringocystadenoma papilliferum (SCAP), which is commonly located on the head and neck and may arise in association with a nevus sebaceus. RAS mutations have been identified in both SCAP and nevus sebaceus.

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[Update on nevi and nevoid skin disorders].

Dermatologie (Heidelb)

May 2023

Universitäts-Hautklinik, Hauptstr. 7, 79104, Freiburg, Deutschland.

Article Synopsis
  • Autosomal dominant inheritance can manifest in a sex-limited manner, where some genetic conditions affect only females despite males carrying the gene.
  • Conditions like Grosshans' white lentiginosis and CELSR1-related lymphedema show this pattern, with affected males remaining asymptomatic but able to transmit the gene.
  • Other unique skin conditions, such as cerebriform sebaceous nevus and transient abdominal telangiectasia in newborns, have distinct genetic causes and presentations that are important for accurate diagnosis.
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Article Synopsis
  • * While most NS remain inactive, there are instances where benign and malignant growths can develop, particularly basal cell and squamous cell carcinomas.
  • * The article highlights the first documented case of malignant melanoma arising from a NS in a 68-year-old man in the U.S., noting that such occurrences are extremely uncommon.
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Atypical Nevus Sebaceus at an Unusual Location Treated with Carbon Dioxide Laser: A Case Report.

Clin Cosmet Investig Dermatol

December 2022

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia.

Article Synopsis
  • * During puberty, NS lesions can evolve into verrucous plaques due to androgen influence and have the potential to develop into secondary tumors, with a small percentage being malignant.
  • * A case study highlighted an 18-year-old male with atypical NS on his chest, diagnosed through histopathology, and successfully treated with CO laser, indicating the importance of further examination for unusual lesions.
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Article Synopsis
  • * While isolated instances of these conditions can often just be observed, their characteristics (like size and placement) may signal the potential for associated syndromes or cranial issues.
  • * This case involved a neonate with NS located within a hair whorl; after ruling out other complications via ultrasound, the lesion was surgically removed at six months for further analysis and confirmation.
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Article Synopsis
  • - Nevus sebaceus is typically a yellow, hairless patch on the head or neck in children that can change to a warty appearance during puberty.
  • - It can lead to secondary tumors, including rare types from mesenchymal origin.
  • - A unique case detailed the removal of a nevus sebaceus from a patient's scalp, revealing a desmoplastic trichilemmoma and a neurofibroma, marking an unusual incidence of these tumors associated with nevus sebaceus.
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Article Synopsis
  • * A case study describes a 73-year-old man who developed a rare aggressive basal cell carcinoma (BSC) within a longstanding NS, presenting as an ulcerative nodule.
  • * Diagnosis involved histopathological analysis and specific immunohistochemical markers, confirming the presence of BSC in the context of the patient's existing NS.
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S2k guideline: Laser therapy of the skin.

J Dtsch Dermatol Ges

September 2022

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Dermatology, Venereology and Allergology, Division of Evidence-Based Medicine (dEBM), Berlin.

Article Synopsis
  • This guideline focuses on enhancing the safety and effectiveness of laser treatments for various skin lesions, particularly emphasizing caution in treating lesions with higher melanocyte levels.
  • It advises against the use of laser therapy for pigmented melanocytic nevi and provides specific recommendations for conditions like lentigines, café-au-lait spots, non-pigmented dermal nevi, and melasma among others.
  • Additionally, the guideline addresses treatments for a wide range of skin issues, including inflammatory dermatoses, wrinkles, scars, benign growths, and different types of vascular and viral lesions.
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Article Synopsis
  • - This study aimed to explore the characteristics of tumors that develop secondary to nevus sebaceus (NS) by analyzing patient data from two hospitals in China and reviewing existing literature.
  • - A total of 497 cases were assessed, revealing that 90.3% were benign tumors, with syringocystadenoma papilliferum being the most prevalent, while basal cell carcinoma was the most common malignant tumor.
  • - The research highlights notable racial differences in the age of onset of secondary malignancies, indicating potential healthcare disparities among Caucasians, Hispanics, and Asians.
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Nevus sebaceus is a benign tumor that is present at birth and is often seen on the scalp or face. Secondary malignant tumors sometimes occur in nevus sebaceus in adulthood. Herein, we present two malignant tumors arose from nevus sebaceus.

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