555 results match your criteria: "Neutropenic Enterocolitis"

Esophageal embryonal rhabdomyosarcoma (ERMS), a rare pediatric cancer, mimicked achalasia in a case involving dysphagia and vomiting. Diagnosis and chemotherapy necessitate careful monitoring due to potential complications. A 12-year-old girl with no prior medical history presented with progressive dysphagia and vomiting.

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Neutropenic enterocolitis (NE) is a potentially life-threatening condition, primarily affecting neutropenic patients with hematologic malignancies. The clinical manifestations of NE in patients receiving antineoplastic drugs range from fever, diarrhea, nausea, vomiting, and abdominal pain to intestinal perforation and shock. We report the case of a 12-year-old boy with acute myelogenous leukemia, undergoing chemotherapy, who presented with an atypical case of NE.

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Article Synopsis
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder causing anemia and thrombosis due to a deficiency of specific membrane proteins, which may lead to severe neutropenia and a risk of neutropenic enterocolitis (NEC).
  • A case is presented of a 31-year-old woman who developed fatal NEC after receiving eculizumab treatment for PNH, experiencing symptoms like abdominal pain, fever, and worsening neutropenia.
  • Despite intensive treatment efforts, she suffered from septic shock and multiple organ failures, ultimately resulting in brain death, illustrating the critical need for early detection and management in patients at high risk for NEC.
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A decision analysis of cancer patients and the consumption of ready-to-eat salad.

Risk Anal

October 2024

Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, Michigan, USA.

Article Synopsis
  • Listeria monocytogenes poses a heightened risk for cancer patients, leading to more severe health outcomes compared to the general public; the neutropenic diet (ND), which avoids fresh produce, is traditionally used to lower this risk.
  • A study developed decision analytic models to evaluate the ND's effects against other dietary practices, finding that the ND resulted in higher rates of neutropenic enterocolitis (NEC) and more negative health impacts overall.
  • The results suggest that safer food handling (SFH) practices are more beneficial and less risky than the ND for cancer patients, leading to a recommendation to adopt the SFH diet instead.
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Article Synopsis
  • Non-hepatic causes of hyperammonaemia are rare, but a case was reported in an adolescent female with severe aplastic anaemia who developed this condition during treatment.
  • She required both intermittent haemodialysis and high-volume continuous veno-venous haemodiafiltration (CVVHDF) to manage the hyperammonaemia, which could not be linked to liver, metabolic, or genetic issues.
  • Ultimately, her hyperammonaemia resolved after surgical resection of her inflamed colon, emphasizing the potential of CVVHDF in treating severe cases of hyperammonaemia not related to liver dysfunction.
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Introduction: Carmustine (BCNU), etoposide, cytarabine, and melphalan (BEAM) are a widely used high-dose chemotherapy regimen for autologous stem cell transplantation transplant (ASCT) in lymphoid malignancies. During BCNU shortages, some centers switched to fotemustine-substituted BEAM (FEAM). Neutropenic enterocolitis (NEC) is a life-threatening complication occurring after intestinal mucosa damage related to intensive chemotherapy.

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Article Synopsis
  • Cancer is the second leading cause of death globally, and as treatment improves, bowel emergencies among cancer patients are becoming more frequent due to longer survival rates.
  • The article focuses on imaging features of various bowel emergencies that occur in cancer patients, including issues like chemotherapy-related colitis and bowel obstructions.
  • Radiologists play a crucial role in diagnosing these emergencies through imaging and helping to guide subsequent treatment decisions.
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Article Synopsis
  • The case study details the occurrence of caudate liver lobe torsion and necrohemorrhagic typhlocolitis in a Patagonian mara, following acute death.
  • Postmortem findings revealed chronic torsion of the hepatic caudate process with fibrous adhesions to the pancreas, as well as significant gastrointestinal damage and bacterial growth.
  • The death was attributed to toxic or bacterial infection related to the liver lobe torsion, and it's suggested that anatomical traits of maras could make them more susceptible to such conditions, similar to rabbits and hares.
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granulomatous typhlocolitis in a horse.

J Vet Diagn Invest

July 2024

Departments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.

A 23-y-old gelding was presented to a veterinary teaching hospital with a history of chronic, refractory diarrhea. Clinically, the horse was in poor body condition, with a thickened and corrugated large intestine identified by transcutaneous abdominal ultrasonography. At postmortem examination following euthanasia, the large colon and cecum had segmental thickening of the intestinal wall with innumerable mucosal ulcers and prominent polypoid mucosal masses.

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Neutropenic enterocolitis (NEC), also referred to as typhlitis, is a condition associated with a high mortality risk and primarily manifests in immunocompromised patients. It is characterized by ulceration, edema, and hemorrhage affecting the bowel wall. The underlying cause of NEC is postulated as an immunocompromised condition that facilitates bacterial infiltration through compromised bowel mucosa.

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Background/aim: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with the functional impairment of multiple joints and the destruction of bone and cartilage. Methotrexate (MTX) is a first-line drug commonly used to treat RA; however, even low doses of MTX can potentially cause rare but severe adverse reactions, such as neutropenic enterocolitis (NE), a life-threatening disease characterized by intestinal mucosal damage and immunodeficiency.

Case Report: Here, we report on an 82-year-old RA patient who developed life-threatening NE after ten years of low-dose MTX treatment.

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Case report: Herbal treatment of neutropenic enterocolitis after chemotherapy for breast cancer.

Open Life Sci

October 2023

Health Management Department, The Affiliated Qingdao Central Hospital of Qingdao University, The Second Affiliated Hospital of Medical College of Qingdao University, No. 127, Si-Liu South Road, Qingdao 266042, Shandong, China.

In this case report, a 53-year-old woman was diagnosed with severe NE after receiving chemotherapy for breast cancer. The patient with breast cancer was treated with a single cycle of docetaxel (140 mg) + epirubicin (130 mg) + cyclophosphamide (0.9 g) chemotherapy.

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What is the role of neutropenia in pediatric cancer patients with pneumatosis intestinalis?

Pediatr Surg Int

May 2023

Division of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 E 16th Ave, Anschutz Medical Campus, Box 323, Aurora, CO, 80045, USA.

Background: We aimed to identify prognostic indicators in pneumatosis intestinalis (PI) in a pediatric oncology population. We hypothesized that neutropenia would be an independent risk factor for adverse outcomes, including the need for abdominal operation to treat PI and for the development of recurrent PI.

Methods: We performed a retrospective review of all patients treated for PI between 2009 and 2019 with a diagnosis of cancer or history of bone marrow transplant (BMT).

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Neutropenic enterocolitis (NE) is a rare and life-threatening condition that typically occurs in patients with hematologic malignancies undergoing intensive chemotherapy, radiation therapy, or bone marrow transplant regimens, predisposing them to profound neutropenia. NE can have a nonspecific clinical presentation and mimic other gastrointestinal disorders such as appendicitis, diverticulitis, or inflammatory bowel disease but is associated with very high morbidity and mortality if not diagnosed and treated promptly. We present the case of a middle-aged female with a recent diagnosis of follicular lymphoma who developed neutropenic enterocolitis after undergoing induction chemotherapy for an autologous stem cell transplant (ASCT).

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Neutropenic Enterocolitis: Case report and literature review.

Rev Gastroenterol Peru

February 2023

Servicio de Oncología Pediátrica, Clínica San Felipe. Lima, Perú.

Typhlitis, is also known as neutropenic enterocolitis, affects the cecum and distal ileum. It was frequently encountered in pediatric patients who were undergoing treatment for leukemia. Nonetheless, it can affect adult patients, regardless of the cause of the immunosuppression.

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Introduction: The primo vascular system (PVS), an intensive network structure, has been claimed to be representative of the acupuncture meridian. Here, we explored the role of the PVS in local enteritis and its modification by acupuncture.

Methods: Chronic cecitis in rabbits was induced by 2,4,6-trinitro-benzene-sulfonic acid (TNBS).

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