2 results match your criteria: "Neurosciences and Mental Health Program Research Institute[Affiliation]"

Stroke in pediatric ECMO: a target for prevention and improvement.

Pediatr Res

September 2022

Paediatric Intensive Care Unit, Department of Critical Care Medicine, University of Toronto, Neurosciences and Mental Health Program Research Institute, Toronto, ON, Canada.

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Objective: Rolandic epilepsy is a common genetic focal epilepsy of childhood characterized by centrotemporal sharp waves on electroencephalogram. In previous genome-wide analysis, we had reported linkage of centrotemporal sharp waves to chromosome 11p13, and fine mapping with 44 SNPs identified the ELP4-PAX6 locus in two independent US and Canadian case-control samples. Here, we aimed to find a causative variant for centrotemporal sharp waves using a larger sample and higher resolution genotyping array.

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