Clinical features and outcomes of patients with diffuse unilateral subacute neuroretinitis treated with oral albendazole.

Purpose: To investigate the clinical features, visual function outcomes, and adverse events in patients with diffuse unilateral subacute neuroretinitis (DUSN) treated with high-dose oral albendazole.

Design: Interventional case series.

Methods: Twelve Brazilian patients, aged 7 through 36 years, with active DUSN in the early or late clinical stage, were recruited for this study between 1999 and 2001.

The white dot syndromes.

Purpose: To review the distinctive and shared features of the white dot syndromes, highlighting the clinical findings, diagnostic test results, proposed etiologies, treatments, and prognosis.

Design: Review.

Methods: Review of the literature.

Early-stage diffuse unilateral subacute neuroretinitis: improvement of vision after photocoagulation of the worm.

Purpose: To evaluate the visual outcome after direct laser photocoagulation of the worm in patients with early-stage diffuse unilateral subacute neuroretinitis (DUSN).

Methods: We report on four patients with DUSN diagnosed in its early stage, in whom the worm was identified and destroyed by laser photocoagulation.

Results: In all the four cases, resolution of the inflammatory multifocal lesions was achieved within 1 month of treatment.

Eye findings of diffuse unilateral subacute neuroretinitis and multiple choroidal infiltrates associated with neural larva migrans due to Bbaylisascaris procyonis.

Purpose: To report childhood infection with Baylisascaris procyonis (raccoon round worm) manifesting as diffuse unilateral subacute neuroretinitis (DUSN) and choroidal infiltrates in association with neurologic disease (neural larva migrans).

Method: Observational case series, one with eye manifestations of DUSN, the other with choroidal infiltrates, both with severe neurologic degeneration.

Results: Indirect immunofluorescence assays on serum and cerebrospinal fluid were positive for B.

Diffuse retinochoroiditis due to Baylisascaris procyonis in Monglian gerbils.

Baylisascaris procyonis, raccoon roundworm, causes a severe retinal lesion in humans. The lesion is termed as diffuse unilateral subacute neuroretinitis (DUSN). To understand the pathogenesis of B.

Nematode infections of the eye: toxocariasis, onchocerciasis, diffuse unilateral subacute neuroretinitis, and cysticercosis.

Nematode infections of the eye are common in different parts of the world, but some are usually encountered only in developing nations, such as onchocerciasis and cysticercosis. Ocular toxocariasis is a well-known cause of unilateral ocular disease affecting mainly children and young adults, and is usually caused by T canis. Prevention of ocular toxocariasis is based on such measures as appropriate health care for dogs and cats, including regular anthelmintic treatments, preventing contamination of the environment with feces, and promoting responsible pet ownership [1,49-51].

Multifocal electroretinography response after laser photocoagulation of a subretinal nematode.

Purpose: To describe multifocal electroretinography findings before and after laser photocoagulation of a subretinal nematode in diffuse unilateral subacute neuroretinitis.

Method: Observational case report. A 45-year-old woman with left eye inflammation, subretinal tracts superior and temporal to the fovea, and a subretinal coiled mobile parasite was treated with laser photocoagulation to destroy the nematode.

Identifying live nematodes in diffuse unilateral subacute neuroretinitis by using the scanning laser ophthalmoscope.

Objective: To describe use of the scanning laser ophthalmoscope (SLO) to identify live nematodes in patients with diffuse unilateral subacute neuroretinitis.

Methods: Infrared, red, and blue illumination (780, 633, and 488 nm, respectively) in an SLO were used to image and evaluate functional retinal status in patients with late-stage diffuse unilateral subacute neuroretinitis. An examination to identify live nematodes was performed in the affected eyes.

Nematode infections of the eye: toxocariasis and diffuse unilateral subacute neuroretinitis.

In many parts of the world, parasitic infections of the eye are a major cause of blindness. The parasites Toxocara canis, Onchocerca volvulus, Taenia solium, Ancylostoma caninum, and Cysticercus celulosae all have been responsible for blinding ocular infections. The nematodes T.

Hypopyon in a patient with presumptive diffuse unilateral subacute neuroretinitis.

Purpose: To report a case of diffuse unilateral subacute neuroretinitis (DUSN) that developed an acute iridocyclitis with hypopyon.

Methods: Case report. We describe a 21-year-old male with clinical diagnosis of DUSN who developed a sudden and severe acute iridocyclitis with hypopyon after one year of follow-up that resolved after treatment with systemic corticosteroids.

Diffuse bilateral subacute neuroretinitis: first patient with documented nematodes in both eyes.

Objective: To describe the first patient with documented evidence of diffuse unilateral subacute neuroretinitis (DUSN) in both eyes.

Methods: A 10-year-old healthy Brazilian girl was first seen with signs of late-stage DUSN in both eyes. A careful search for a nematode was performed in each eye.

Diffuse unilateral subacute neuroretinitis.

Background: Diffuse unilateral subacute neuroretinitis (DUSN) is an inflammatory disorder of the retina thought to be caused by a motile worm. It initially presents with unilateral recurring crops of gray-white retinal lesions and mild to severe inflammation. Over a period of months, diffuse retinal pigment epithelium (RPE) changes, arteriolar attenuation, and optic atrophy will develop.

Diffuse unilateral subacute neuroretinitis in Europe.

Background: Diffuse unilateral subacute neuroretinitis is thought to be caused by a solitary helminth migrating within the subretinal space. Laser photocoagulation of the located worm is the preferred mode of therapy.

Methods: We describe the clinical and electrophysiological features of a case of a 15-year-old Caucasian male with a longstanding diffuse unilateral subacute neuroretinitis (DUSN), in whom two worms were seen in the fundus examination.

[An attempt to extract an intraretinal nematode located in the papillomacular bundle].

Background: The nematode infection of the retina is a rare disease with sight threatening prognosis. Untreated eyes usually become blind. There are different types of clinical progression: granuloma causing tractional detachment chronic inflammation called diffuse unilateral subacute neuroretinitis (DUSN) and rapid loss of vision named "ocular wipe-out syndrome".

Antihelminthic drugs in diffuse unilateral subacute neuroretinitis.

Purpose: To evaluate the efficacy of ivermectin and thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis.

Methods: Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with thiabendazole.

[Unilateral diffuse subacute neuroretinitis].

The authors report two cases of diffuse unilateral subacute neuroretinitis. The evolution of the illness, here at late stage in both cases, and the different paraclinical investigations will be presented.