259 results match your criteria: "Neurological Sequelae of Infectious Endocarditis"

[Complications of infective endocarditis].

Rev Prat

June 2024

Département de cardiologie, CHU Amiens, Amiens, France.

COMPLICATIONS OF INFECTIVE ENDOCARDITIS. The high in-hospital mortality of patients with infective endocarditis (about 20%) is mainly due to its complications. These complications are essentially of cardiac, neurological, and infectious origin.

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Stroke and intracranial hemorrhage (ICH) are serious complications that are difficult to manage during surgery for active infectious endocarditis (AIE). Relevant society guidelines still recommend delaying the cardiac surgery for AIE with ICH for 4 weeks. Some early studies indicated that the mortality rate decreases when cardiac surgery for ICH is delayed.

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Article Synopsis
  • A study of infective endocarditis (IE) in Spain revealed that 19.8% of patients also suffered from acute stroke, with most cases being ischemic strokes.* -
  • Patients with stroke had higher risks of complications, surgical needs, and mortality rates compared to those without stroke, indicating more severe health impacts.* -
  • Factors like the location of infection and the presence of other medical issues were found to increase the likelihood of stroke and its associated mortality in these patients.*
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Infective endocarditis (IE) is a life-threatening infection predominantly affecting the endocardium and heart valves, commonly seen in older patients and those with pre-existing cardiac conditions. Although rare in younger individuals with intact cardiac valves, certain structural heart diseases such as hypertrophic obstructive cardiomyopathy (HOCM) can increase the risk. We present a unique case of a 39-year-old female with a known history of HOCM, a condition characterized by abnormally thickened cardiac muscle primarily affecting the left ventricle.

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Brucellosis (undulant fever) is a zoonotic infection caused by Brucella species. It typically presents with fever, malaise, night sweats, and arthralgia. One of its rare complications is infective endocarditis, which occurs in approximately 1.

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Septic Arthritis of the Spinal Facet Joint: Review of 117 Cases.

Open Forum Infect Dis

March 2024

Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Article Synopsis
  • Septic arthritis of the spinal facet joints is gaining recognition, especially with advancements in MRI, but its characteristics and treatment options remain unclear.
  • A review of 101 past cases and 16 new cases revealed that most patients experienced fever and back or neck pain, with many showing signs of bacteremia and abscesses.
  • Despite complications like abscesses, the prognosis is generally positive, with a 98% survival rate and minimal long-term neurological issues.
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Background: Infective endocarditis (IE) is a rare, but potentially fatal, infectious disease. One of the common complications of IE is the embolization of endocardial vegetation with subsequent intracerebral artery obstruction that causes acute ischemic stroke. Herein, we present a case report of a patient presenting with a neurological manifestation that turned out to be a complication of IE.

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Article Synopsis
  • The case discusses a rare type of infectious endocarditis caused by a specific Streptococcus species, leading to complications.
  • A young woman experienced a sudden headache and was diagnosed with subarachnoid hemorrhage and an aneurysm in the brain, linked to the endocarditis.
  • After undergoing treatment, including antibiotics and surgery, she recovered without neurological issues, highlighting that this type of endocarditis can lead to delayed intracranial aneurysms and that endovascular treatments can be effective.
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infective endocarditis complicated by brain abscess in a patient with a congenital bicuspid aortic valve: a case report.

Eur Heart J Case Rep

December 2023

Department of Infection and Acute Medicine, St George's Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK.

Background: Infective endocarditis is associated with significant morbidity and mortality. Oral trauma through dental procedures can result in infective endocarditis through displacement of commensal organisms into the bloodstream. is an oral commensal and is rarely implicated as a cause of infective endocarditis but should be considered in febrile patients with a recent history of odontological procedures.

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Case Report: Cardiovascular Manifestations due to Flea-Borne Typhus.

Am J Trop Med Hyg

January 2024

Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California.

Flea-borne typhus is a vector-borne disease caused by Rickettsia typhi that occurs worldwide, except in Antarctica. In the United States, most cases are restricted to California, Hawaii, and Texas. The syndrome is characterized by nonspecific signs and symptoms: fever, headache, rash, arthralgia, cough, hepatosplenomegaly, diarrhea, and abdominal pain.

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Multiple cerebral septic emboli sourcing from a ventricular assist device: a case report.

AME Case Rep

September 2023

Biomedical and Experimental Department, Faculty of Medicine, University of Medicine, Tirana, Albania.

Article Synopsis
  • - Patients with portable cardiac devices face a high risk of serious infections and neurological complications, despite being monitored and anticoagulated.
  • - A middle-aged patient with heart failure and a ventricular assist device developed signs of infection and neurological issues, confirmed through CT scans and blood cultures.
  • - The patient was successfully treated for these complications and emphasized the need for greater awareness and adherence to monitoring guidelines for patients with external heart devices.
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Introduction And Importance: Fever of unknown origin (FUO) in children poses a complex challenge for doctors. It involves a broad spectrum of potential diagnoses, with infectious diseases being the predominant culprits, followed by connective tissue disorders and malignancies.

Case Presentation: A 4-year-old boy with a prior diagnosis of a congenital bicuspid aortic valve was admitted to our hospital after experiencing two months of intermittent high-grade fever, severe nighttime headaches, and episodes of nausea and vomiting.

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Introduction: Infective endocarditis (IE) is a serious problem with high morbidity and mortality. However, there is a paucity of data regarding its epidemiology in non-high-income settings. Here, we described the characteristics of patients with IE.

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Early versus Delayed Surgery in Patients with Left-Sided Infective Endocarditis and Stroke.

J Cardiovasc Dev Dis

August 2023

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany.

Background: Timing of surgery remains controversial in patients with infective endocarditis and stroke. Guidelines on infective endocarditis suggest delaying surgery for up to 4 weeks. However, with early heart failure due to progression of the infection or recurrent septic embolism, urgent surgery becomes imperative.

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This case report presents a rare and intricate clinical scenario involving a 58-year-old male with a history of hypertension, intravenous drug use (IVDU), and cocaine abuse. The patient presented with profound hypotension and symptoms suggestive of impending shock. Septic workup revealed in all four blood culture bottles, confirming a diagnosis of infective endocarditis (IE).

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Whipple's disease is an uncommon chronic systemic disease caused by . The most characteristic findings of late Whipple's disease include diarrhoea, abdominal pain, weight loss, and arthralgias, however, other clinical findings can occur, including lymphadenopathy, fever, neurologic manifestations, myocarditis and endocarditis. The aim of the present study was to systematically review all cases of Whipple's disease-associated infective endocarditis (IE) in the literature.

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Key Clinical Message: Atrial myxoma is a rare disease but has a broad clinical presentation and complication that involves several systems- heart, lungs, brain, and systemic. An interdisciplinary approach is very important to optimize the outcome in patients with atrial myxomas. A thorough examination by primary care providers is crucial.

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Infective endocarditis (IE) is an infection of the heart's endocardial surface, heart valves, or implanted cardiac devices, with the most common causative organism being . The clinical presentation of IE can be variable, with some patients presenting with multisystemic complications, including renal, pulmonary, cutaneous, and neurologic complications. Cerebral infarction is the most common complication of IE.

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Background: Cerebral embolic events (CEEs) are common complications of infective endocarditis (IE), and their presence can modify diagnosis and therapeutic plans. The aim of the present study was to assess the role of cerebral imaging (Cer-Im) on diagnosis and management of patients with suspected IE.

Methods: This study was conducted at the Lausanne University Hospital, Lausanne, Switzerland, from January 2014 to June 2022.

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Background: Infective endocarditis is a severe and potentially lethal cardiac disease. Recognition of the clinical features of endocarditis, such as distant embolisation, and adequate treatment should be initiated promptly given the grim perspective of upcoming virulent pathogens.

Methods: We report on our registry-based experience with outcomes of consecutive patients with infective endocarditis with distant embolisation.

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Adding Fuel to the Fire: Infective Endocarditis and the Challenge of Cerebrovascular Complications.

Curr Cardiol Rep

May 2023

Department of Neurology, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Box 359775, Seattle, WA, 98104-2420, USA.

Purpose Of Review: Infective endocarditis is a deadly disease and made more deadly by neurologic complications. We review the cerebrovascular complications of infective endocarditis and focus our discussion on medical and surgical management.

Recent Findings: While management of stroke in the setting of infective endocarditis differs from standard stroke treatment, mechanical thrombectomy has proven safe and successful.

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In the following case review, we present a 49-year-old male without a history of injection drug (IDU) use nor any known structural heart disease, who developed left-sided pseudomonal infectious endocarditis. The only known risk factors were urinary tract infection (UTI) with secondary bacteremia and prolonged healthcare contact with admission to the intensive care unit. Infectious endocarditis (IE) is the infection of the endocardium.

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Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis.

Ann Intensive Care

December 2022

Department of Intensive Care Medicine, AP-HP. Nord, Hôpital Bichat - Claude Bernard, Paris, France.

Background: Neurological complications are associated with poor outcome in patients with infective endocarditis (IE). Although guidelines recommend systematic brain imaging in the evaluation of IE patients, the association between early brain imaging findings and outcomes has never been evaluated in critically ill patients. We aimed to assess the association of CT-defined neurological complications with functional outcomes of critically ill IE patients.

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Background: Aspergillus endocarditis (AE) is a rare fatal infection. The infection is often reported in patients with prosthetic heart valves, immunosuppressed, broad-spectrum antimicrobial use regimens, and drug abusers.

Methods: Herein, we report a rare case of native mitral valve AE in a 63-year-old man, with a probable COVID-19-associated invasive pulmonary aspergillosis nine months ago treated with antifungals.

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