2 results match your criteria: "Neurological Department Hospital University Center of Monastir[Affiliation]"
Mitochondrial DNA and Alzheimer's disease: a first case-control study of the Tunisian population.
Mol Biol Rep
March 2022
Laboratory of Genetics, Immunology and Human Pathology, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunis, Tunisia.
Article Synopsis
- Alzheimer's disease (AD) is a major global health issue, and this study investigates the role of mitochondrial DNA in relation to its onset, specifically within the Tunisian population.
- Researchers analyzed 159 single-nucleotide polymorphisms (SNPs) from mitochondrial DNA in 254 individuals, alongside assessing the presence of the APOE ε4 gene, known to increase AD risk.
- The study found no significant link between mitochondrial haplogroups and AD, but discovered two specific SNPs that were associated with the disease, while confirming APOE ε4 as a significant risk factor.
Multiple and recurrent cerebral infarctions in a patient with idiopathic thrombocytopenic purpura.
J Clin Neurosci
August 2017
Neurological Department Hospital University Center of Monastir, 5000 Monastir, Tunisia.