107 results match your criteria: "Neuroimmunology Clinic[Affiliation]"
Brain histopathology in three cases of Susac's syndrome: implications for lesion pathogenesis and treatment.
J Neurol Neurosurg Psychiatry
May 2015
Brain & Mind Research Institute, Sydney, New South Wales, Australia Department of Neuropathology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
IL-17 and related cytokines involved in the pathology and immunotherapy of multiple sclerosis: Current and future developments.
Cytokine Growth Factor Rev
August 2014
Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn(2)), University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Multiple sclerosis (MS), an autoimmune neurological disorder, is driven by self-reactive T helper (Th) cells. Research on the role of Th17 lymphocytes in MS pathogenesis has made significant progress in identifying various immunological as well as environmental factors that induce the differentiation and expansion of these cells, different subsets of Th17 cells with varying degrees of pathogenicity, and the role of the secreted effector cytokines. While approved therapies for MS offer significant benefit to patients, there remain unmet needs.
View Article and Find Full Text PDFBaló's concentric sclerosis.
Lancet Neurol
July 2014
Department of Neuroinflammation, University College London Institute of Neurology, Queen Square MS Centre, London, UK.
Baló's concentric sclerosis is often regarded as a rare variant of multiple sclerosis. Patients with this disorder present with acute or subacute neurological deterioration, with MRI showing one or more concentrically multilayered ring-like lesions usually in the cerebral white matter. Historically, Baló's concentric sclerosis was thought fatal in all cases.
View Article and Find Full Text PDFMultiple sclerosis is associated with psoriasis. A case-control study.
J Neurol Sci
March 2014
Neuroimmunology Clinic of the Department of Neurology, Tel Aviv Sourasky Medical Center, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:
Background: MS and psoriasis are both autoimmune diseases putatively mediated mainly by T cells.
Objective: We conducted a case control study to investigate whether patients with MS have a high rate of comorbid psoriasis.
Methods: The cohort consisted of 214 consecutive MS patients and a control group of 192 consecutive patients with headache.
Nightly sublingual tizanidine HCl in multiple sclerosis: clinical efficacy and safety.
Clin Neuropharmacol
May 2010
Neuroimmunology Clinic, Department of Neurology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Background: Approximately 90% of patients with multiple sclerosis (MS) experience spasticity during their lifetime. Tizanidine HCl is an alpha2 adrenergic agonist indicated for treating spasticity due to MS or spinal cord injury.
Objectives: To compare the clinical efficacy and safety of once-nightly sublingual versus oral tizanidine HCl (8 mg) or placebo in MS patients with spasticity requiring treatment.
The limitations of immunosuppressant therapy in Multiple Sclerosis.
J Clin Neurosci
November 2000
Department of Clinical Neuroscience and Neuroimmunology Clinic, St Vincent's Hospital, Victoria, Australia.
Preliminary observations on APOE epsilon4 allele and progression of disability in multiple sclerosis.
Arch Neurol
December 1999
Department of Neurology and Neuroimmunology Clinic, Tel Aviv Medical Center, Israel.
Background: Apolipoprotein E expression is increased in regenerating neural tissue and the APOE epsilon4 allele is associated with impaired neuronal repair. Since repair is essential for the restoration of central nervous system function following multiple sclerosis (MS) relapses, APOE genotype may influence clinical progression of the disease.
Objective: To examine the association of the APOE genotype with disease susceptibility and progression in MS.