3 results match your criteria: "Neurodegenerative Diseases Clinical Laboratory[Affiliation]"

Article Synopsis
  • The study investigates the link between Parkinson's disease (PD) and cardiometabolic conditions as the aging population increases the prevalence of PD.
  • A case-control study analyzed data from 781 PD patients and 1,000 controls, looking at factors like diabetes, hypertension, dyslipidemia, and BMI.
  • Results showed that systemic arterial hypertension (SAH) increased the risk of PD while obesity appeared to have a protective effect, suggesting a complex interaction between these conditions and PD development.
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Frontal functional connectivity and disease duration interactively predict cognitive decline in Parkinson's disease.

Clin Neurophysiol

February 2021

Neuropsychology Laboratory, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez (INNN), Mexico City, Mexico; Faculty of Psychology, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico. Electronic address:

Objective: Cognitive decline does not always follow a predictable course in Parkinson's disease (PD), with some patients remaining stable while others meet criteria for dementia from early stages. Functional connectivity has been proposed as a good correlate of cognitive decline in PD, although it has not been explored whether the association between this connectivity and cognitive ability is influenced by disease duration, which was our objective.

Methods: We included 30 patients with PD and 15 healthy controls (HC).

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