27,353 results match your criteria: "Nephrolithiasis"

Association of Red Blood Cell Distribution Width to Albumin Ratio With the Prevalence of Kidney Stones Among the General Adult Population.

Immun Inflamm Dis

November 2024

Department of Urology, The Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou Maternal and Child Health Care Hospital, Wenzhou, China.

Background: The red blood cell distribution width (RDW) and serum albumin levels are potential indicators of inflammatory conditions. However, the relationship between the RDW to albumin ratio (RAR) and the prevalence of kidney stones in the general adult population is not yet established.

Methods: This study utilized data from the 2007 to 2018 National Health and Nutrition Examination Survey (NHANES) project.

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Point-of-Care Ultrasound of the Urinary Tract.

Med Clin North Am

January 2025

Department of Acute Medicine, Basingstoke and North Hampshire Hospital, Aldermaston Road, Basinngstoke RG24 9NA, UK.

Point-of-care ultrasound (POCUS) provides immediate and useful information that aids clinical decision making at the bedside. The purpose of this article is to describe how POCUS can be integrated in the evaluation of the urinary system. In the first section, the authors aim to describe image acquisition and typical sonoanatomy of the kidney and bladder.

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Introduction: An evaluation and prognosis of complications of different treatment options in patients with staghorn stones are necessary to choose optimal surgical strategy and perioperative prophylaxis on individualized basis. Intra- and postoperative thrombotic and hemorrhagic complications are not still well-studied in modern operative urology.

Aim: To explore the influence of morpho-densitometry changes of blood platelets on perioperative thrombotic and hemorrhagic complications in patients with staghorn nephrolithiasis after percutaneous nephrolithotomy (PCNL).

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The potential role of alkaline diets in prevention of calcium oxalate kidney stone formation.

Food Funct

December 2024

Nutrition and Food Sciences Department, Food Industries and Nutrition Institute, National Research Centre, Dokki 12622, Cairo, Egypt.

Formation of kidney stones is considered a major global problem. Diet plays an important role in the management of kidney stone formation. The main goal of the present research was to evaluate the protective role of fruit and vegetable mixtures as models of an alkaline diet on formation of kidney stones in rats and to conduct molecular docking study.

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Article Synopsis
  • Percutaneous nephrolithotomy (PNL) can cause damage to blood vessels and kidney tissue, leading to impaired kidney function, and this study focuses on the biomarker NGAL associated with acute kidney injury.
  • The study involved 46 patients whose NGAL levels were measured before and after PNL, exploring how factors like type of kidney stone and procedure duration affected kidney function.
  • Findings indicate that significant kidney function impairment, particularly with staghorn stones, is linked to high initial NGAL levels, suggesting that NGAL testing could effectively assess kidney damage immediately following PNL.
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Introduction: Today it is urgent to introduce into clinical practice more advanced methods of kidney stone treatment with high indicators of their effectiveness and safety while minimizing the risk of repeated interventions. The goal of effective treatment of kidney stones is to completely rid the patient of stones and complaints, to eliminate organ dysfunction, using minimally invasive treatment methods that reduce the patients hospital stay and the risk of complications. However, there are only few studies comparing the clinical efficacy and safety of modern methods of surgical treatment of kidney stones 2 to 3 cm in size.

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Introduction: Horseshoe kidney is often associated with ureteropelvic junction obstruction and nephrolithiasis. Retrograde intrarenal surgery (RIRS) is becoming one of the main treatment options for large stones in such patients.

Aim: To study the results of RIRS in patients with horseshoe kidney.

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Retrograde intrarenal surgery (RIRS) is a type of endoscopic intervention on the kidneys performed using a semi-rigid or flexible fiber optic endoscope. RIRS is recommended by national clinical guidelines for stone management sized up to 20 mm. However, like any other surgical intervention, RIRS is associated with the risk of complications.

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Article Synopsis
  • Kidney stones affect over 12% of the global population, and their formation mechanisms are not fully understood.
  • Recent analysis of magnesium (Mg) isotopes in human kidney stones reveals a range of Mg enrichment, providing insights into the biological processes involved in their formation.
  • The study suggests that Mg isotopic fractionation is linked to protein-mediated transport in the body, which may explain the inhibitory effect of Mg on kidney stone formation.
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Undetectable renal stone on computed tomography.

Urol Case Rep

November 2024

Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510230, China.

Noncontrast computed tomography(CT) is commonly recommended for the diagnosis of suspected renal stones. In this paper, we present a case of a renal stone that cannot be detected by CT. The stone was made of n-butyl α-cyanoacrylate, a kind of surgical adhesives commonly used in partial nephrotomy.

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Purpose: This prospective study aimed to identify risk factors associated with progression to stage 3 chronic kidney disease (CKD) and the occurrence of kidney stone formation or growth following nephrectomy for urolithiasis.

Materials And Methods: From January 2006 to May 2013, patients undergoing nephrectomy for urolithiasis were enrolled. Renal function was assessed using estimated glomerular filtration rate (eGFR) via the Chronic Kidney Disease Epidemiology Collaboration equation, while kidney stone events were detected using computed tomography.

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Background: Although blood urine is frequently observed in dromedary camels, little attention is gained and only it was reported as case reports.

Aim: This study was carried out to examine dromedary camels suffering from red urine syndrome from the points of clinical, etiological, hematobiochemical, ultrasonographic, and pathological characteristics.

Methods: Thirty-one camels with red urine and fifteen controls were enrolled.

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Background Point-of-care ultrasound (PoCUS) is an imaging modality with many inherent benefits, such as increased patient satisfaction, cost savings, and elimination of delays in diagnosis. The popularity of this bedside imaging technique has increased in recent years, and its scope of use for diagnostics and procedures has expanded in many specialties. Research question Can increased implementation of PoCUS within the Geisinger Health System (GHS) reduce the need for other more expensive, time-consuming, and potentially harmful imaging techniques? Methods Investigations were carried out on the uses of PoCUS established in the literature as a bedside diagnostic tool for specific pathologies such as pneumonia, nephrolithiasis, and various fractures.

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Kidney stones or Nephrolithiasis are the most common health condition associated with the urinary system. Dietary factors stand as important factors in the occurrence and development of kidney stones. This study aimed to examine the potential link between dietary insulin index (DII) and dietary insulin load (DIL) with prevalence of kidney stones.

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Objectives: Evaluation of the validity of the Quadruple-D score in the prediction of success in pediatric stone disease.

Materials And Methods: Of the 292 children treated with SWL between 2007 and 2023, a total of 158 children who had adequate follow-up data and evaluated with non-contrast computed tomography before SWL, were included in the study. Parameters were calculated for each of the stone volume (SV), skin-to-stone distance (SSD), stone density (SD) and stone location (SL) variables.

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Calcium oxalate (CaOx) nephrolithiasis constitutes approximately 75% of nephrolithiasis cases, resulting from the supersaturation and deposition of CaOx crystals in renal tissues. Despite their prevalence, precise biomarkers for CaOx nephrolithiasis are lacking. With advances in high-throughput sequencing, we aimed to identify biomarkers of CaOx nephrolithiasis by combining two CaOx nephrolithiasis datasets (GSE73680 and GSE117518).

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Calcium oxalate (CaOx) kidney stones pose a global health challenge due to their high prevalence and recurrence rates. While cell death mechanisms such as ferroptosis are known to play a crucial role in stone formation, the precise underlying mechanisms remain enigmatic. Aldehyde dehydrogenase 2 (ALDH2) is a metabolic enzyme of the ferroptosis product 4-hydroxy-2-nonenal (4-HNE).

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Our comprehensive genomic investigation employing tree shrew calcium oxalate stone models unveils intricate links between kidney stone formation and diverse physiological systems. We identify a constellation of genes whose expression patterns point to multifaceted interactions among cardiovascular health, renal fibrosis, and bone homeostasis in the pathogenesis of renal calculi. Key players include CHIT1, TNFRSF18, CLEC4E, RGS1, DCSTAMP, and SLC37A2, which emerge as pivotal actors in arteriosclerosis, renal fibrosis, and osteoclastogenesis respectively, showcasing the complexity of stone disease.

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Flexible and navigable suction ureteral access sheath (FANS) is a potential game changer in flexible ureteroscopy (FURS). The influence of sheath size on outcomes needs research. The primary aim was to analyze 30-day single stage stone free status (SFS), zero fragment rate (ZFR) and complications when using 10/12Fr sheaths vis a vis other sheath sizes.

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Article Synopsis
  • Primary hyperparathyroidism is an endocrine disorder that can cause high calcium levels, often found without symptoms in patients.
  • A 47-year-old male case study highlights the mild presentation of significant hormonal issues, where fasting may have contributed to kidney stone development despite no major symptoms initially.
  • After surgery to remove a large parathyroid adenoma, the patient faced additional complications but ultimately achieved biochemical remission, demonstrating the importance of vigilant monitoring in similar cases.
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Kidney stones pose a significant healthcare burden worldwide. Dyslipidemia is a risk factor for kidney stones, but the relationship between remnant cholesterol (RC) and kidney stone risk is unknown. We aimed to investigate the association between RC and the risk of incident kidney stones.

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Mini-endoscopic combined intrarenal surgery (ECIRS) offers improved advantages in the treatment of renal stones. However, the factors influencing the operative time remain poorly understood. This study aimed to identify the factors that enhance treatment planning and minimize complications.

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Imaging in Urolithiasis.

Urol Clin North Am

February 2025

Department of Medicine, Surgery and Pharmacy, University of Sassari, Viale S. Pietro 10, Sassari 07100, Italy; Department of Radiology, James Cook University Hospital, Marton Road, Middlesbrough TS43BM, UK. Electronic address:

Urolithiasis has high incidence in industrialized countries (0.5% in Europe and North America). Its high incidence along with the severity of clinical symptoms makes nephrolithiasis an important consideration in patients with acute abdominal pain.

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Objective: Sapropterin dihydrochloride is the first drug for the therapy of phenylketonuria, which is a rare disease that occurs one of 10,000-15,000 newborns. As a result, detailed and comprehensive reports on the safety of sapropterin in large, real-world populations are required. The purpose of this study is to undertake a complete analysis of sapropterin's adverse events (AEs) using the FDA Adverse Event Reporting System (FAERS) database.

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