844 results match your criteria: "Naval Center for Combat & Operational Stress Control[Affiliation]"
Mil Med
May 2022
Pulmonary and Critical Care Medicine, Naval Medical Center Camp Lejeune, Camp Lejeune, NC 28547, USA.
The coronavirus 2019 (COVID-19) pandemic continues to be a threat to global health, including the health of deployed armed forces. Servicemembers had to adjust to the "new normal" while maintaining the interests of the nation's security as well as that of our host nation partners. This commentary examines how Special Operations Forces operating within four different regions worldwide leveraged the challenges presented by the onset of this pandemic in maintaining stability, sustaining a ready force, and operating forward deployed.
View Article and Find Full Text PDFMil Med
January 2022
Department of otolaryngology/head and neck surgery, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Introduction: It has been shown that combat environment exposure, including burn pits that produce particulate matter 2.5 (PM2.5), is associated with lower respiratory tract disease in the military population with increased hypothetical risk of upper respiratory disease, but no study has been done that examines the effects of non-combat environmental exposures on the development of chronic rhinosinusitis (CRS) in the active duty population.
View Article and Find Full Text PDFJ Fam Psychol
August 2022
Department of Psychology.
The objective of this study was to predict marital instability from a range of risk and protective factors in a large, representative cohort of military couples participating in the Millennium Cohort Family Study. Online and paper surveys were administered to service members and their spouses in 2011-2013, which captured couples' demographic and background characteristics, family stressors, military experiences, and mental health risk factors as well as protective factors including family communication, and military support and satisfaction. Approximately 3 years later, change in marital status was examined among participants who completed a follow-up survey ( = 6,494 couples).
View Article and Find Full Text PDFMil Med
January 2023
VA San Diego Healthcare System, San Diego, CA 92161, USA.
Introduction: Rates of overweight and obesity have increased in the military, particularly in the U.S. Navy.
View Article and Find Full Text PDFAnn Epidemiol
March 2022
Naval Health Research Center, Deployment Health Research Department, San Diego, CA. Electronic address:
Purpose: The Millennium Cohort Study, the US Department of Defense's largest and longest running study, was conceived in 1999 to investigate the effects of military service on service member health and well-being by prospectively following active duty, Reserve, and National Guard personnel from all branches during and following military service. In commemoration of the Study's 20th anniversary, this paper provides a summary of its methods, key findings, and future directions.
Methods: Recruitment and enrollment of the first 5 panels occurred between 2001 and 2021.
Expert Opin Drug Discov
March 2022
Optical Sciences Division, Naval Research Laboratory, Washington, DC, USA.
Introduction: SARS-CoV-2 is a highly infectious and deadly coronavirus whose study requires the use of a biosafety level 3 (BSL-3) containment facility to investigate viral biology and pathogenesis, which limits the study of live virus and slows progress toward finding suitable treatments for infection. While vaccines from several companies have proven very effective in combating the virus, few treatments exist for those who do succumb to the viral-induced systemic disease called COVID-19.
Areas Covered: This short review focuses on fluorescent quantum dot-based modeling of SARS-CoV-2.
BMC Infect Dis
November 2021
Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, USA.
Background: Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to assess the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, using data from all available randomized clinical trials, including unpublished and ongoing trials (Open Science Framework, https://doi.org/10.
View Article and Find Full Text PDFPrehosp Emerg Care
January 2023
Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
As the wars in Iraq and Afghanistan end, the US military has begun to transition to the multi-domain operations concept with preparation for large scale combat operations against a near-peer adversary. In large scale combat operations, the deployed trauma system will likely see challenges not experienced during the Global War on Terrorism. The development of science and technology will be critical to close existing capability gaps and optimize casualty survival.
View Article and Find Full Text PDFMil Med
May 2023
Naval Center for Combat & Operational Stress Control, San Diego, CA 92134, USA.
Introduction: Despite a wide literature describing the impact of PTSD on military personnel, there is limited information concerning the results of PTSD treatment within military clinics mental health. Having such information is essential for making predictions about service members' chances of recovery, choosing best treatments, and for understanding if new interventions improve upon the standard of care.
Materials And Methods: We reviewed data from the Psychological Health Pathways (PHP) database.
Prosthet Orthot Int
February 2022
Medical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, San Diego, CA.
Background: Military amputee patient care programs offer extensive services, including advanced prosthetic devices, to restore function and improve quality of life (QOL) among veterans and service members with combat-related limb loss, but research on satisfaction with these devices is limited.
Objective: To assess prosthesis satisfaction and QOL in US service members and veterans with combat-related major lower-limb amputation.
Study Design: Cross-sectional study.
BMJ Mil Health
January 2024
Directorate for Operational Readiness & Health, Naval Health Research Center, San Diego, CA, USA.
Introduction: Military members are exposed to high cumulative physical loads that frequently lead to injury. Prescribed footwear and orthoses have been used to prevent injury. The purpose of this systematic review with meta-analysis was to assess if prescribed prophylactic footwear or foot orthoses reduced the risk of lower extremity injury in military tactical athletes.
View Article and Find Full Text PDFOTA Int
December 2021
USU-WRNMMC Department of Surgery.
Unlabelled: In combat casualty care, tranexamic acid (TXA) is administered as part of initial resuscitation effort; however, conflicting data exist as to whether TXA contributes to increased risk of venous thromboembolism (VTE). The purpose of this study is to determine what factors increase risk of pulmonary embolism after combat-related orthopaedic trauma and whether administration of TXA is an independent risk factor for major thromboembolic events.
Setting: United States Military Trauma Centers.
ACS Synth Biol
November 2021
U.S. Army Combat Capabilities Development Command Chemical Biological Center, 8198 Blackhawk Road, Aberdeen Proving Ground, Maryland 21010, United States.
Many bacterial mechanisms for highly specific and sensitive detection of heavy metals and other hazards have been reengineered to serve as sensors. In some cases, these sensors have been implemented in cell-free expression systems, enabling easier design optimization and deployment in low-resource settings through lyophilization. Here, we apply the advantages of cell-free expression systems to optimize sensors based on three separate bacterial response mechanisms for arsenic, cadmium, and mercury.
View Article and Find Full Text PDFCureus
September 2021
Dermatology, Naval Hospital Camp Pendleton, Camp Pendleton, USA.
Bupropion is an oral antidepressant that is commonly used to treat various mood disorders. Its therapeutic mechanism of action results from inhibiting the reuptake of norepinephrine and dopamine. Bupropion is generally well-tolerated and patients usually experience no side effects or mild adverse events.
View Article and Find Full Text PDFSleep Health
December 2021
Sleep, Tactical Efficiency, and Endurance Laboratory, Warfighter Performance Department, Naval Health Research Center, San Diego, California, USA; Leidos, Inc., San Diego, California, USA.
Objective: The presence of insomnia in the general military population is not well known. This study aimed to determine the prevalence of probable clinical insomnia and identify factors leading to new-onset insomnia and/or sleep medication use in a large military population.
Design: Cross-sectional and longitudinal analyses of a prospective cohort study.
Front Microbiol
September 2021
US Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, Washington, DC, United States.
New methods for antimicrobial design are critical for combating pathogenic bacteria in the post-antibiotic era. Fortunately, competition within complex communities has led to the natural evolution of antimicrobial peptide (AMP) sequences that have promising bactericidal properties. Unfortunately, the identification, characterization, and production of AMPs can prove complex and time consuming.
View Article and Find Full Text PDFIntroduction: A 6-week mindfulness training course, the Mind-Body Medicine (MBM) pilot program for staff, was implemented at a large military treatment facility to examine the preliminary efficacy of the program in reducing stress and burnout in military healthcare professionals.
Materials And Methods: A retrospective analysis was conducted of data collected from a single-arm prospective MBM pilot program. The program was designed to help staff members increase their awareness of burnout and its consequences and to learn how to utilize mindfulness-based self-care practices as a means for reducing stress and preventing burnout at work.
Background: Virtual health (VH) may enhance mentorship to remote first responders. We evaluated the feasibility of synchronous bidirectional VH to mentor life-saving procedures performed by deployed novice providers.
Methods: Video teleconferencing (VTC) was established between the USNS Mercy (T-AH 19) underway in the Pacific Ocean to Naval Medical Center San Diego using surgeon teleconsultation.
Mil Med
March 2023
Biobehavioral Sciences Lab, Warfighter Performance Department, Naval Health Research Center, San Diego, CA 92106, USA.
Objective: The aim of this study was to determine the unique and combined associations of various military stress exposures with positive and negative mental health symptoms in active duty service members.
Materials And Methods: We investigated 87 male U.S.
Mil Psychol
September 2021
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, San Antonio, Texas, USA.
Psychiatric aeromedical evacuations are one of the leading causes of medical related evacuations of US military personnel from combat. Currently, no studies have examined gender and marital status of individuals who were evacuated from combat for a psychiatric diagnosis. Psychiatric aeromedical evacuation data from 5,957 United States military personnel deployed to Iraq or Afghanistan between 2001 and 2013 were analyzed using chi-square tests of independence, odds ratios (OR), and standardized residuals.
View Article and Find Full Text PDFAntibiotics (Basel)
August 2021
Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA.
Background: Pseudomonas aeruginosa (PsA) is a common etiology of bacteria-mediated lower respiratory tract infections, including pneumonia, hospital acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP). Given the paucity of novel antibiotics in our foreseeable pipeline, developing novel non-antibiotic antimicrobial therapies saliently targeting drug resistant PsA isolates remains a priority. Lytic bacteriophages (or phages) have come under scrutiny as a potential antimicrobial for refractory bacterial infections.
View Article and Find Full Text PDFJ Int Soc Sports Nutr
August 2021
Military Nutrition Division, US Army Research Institute of Environmental Medicine, 10 General Greene Ave, Natick, MA, 01760, USA.
Brief Bioinform
November 2021
Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA.
The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has led to a dramatic loss of human life worldwide. Despite many efforts, the development of effective drugs and vaccines for this novel virus will take considerable time. Artificial intelligence (AI) and machine learning (ML) offer promising solutions that could accelerate the discovery and optimization of new antivirals.
View Article and Find Full Text PDFCell Discov
August 2021
International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University / Naval Medical University, Shanghai, China.
Coronavirus disease 2019 (COVID-19), driven by SARS-CoV-2, is a severe infectious disease that has become a global health threat. Vaccines are among the most effective public health tools for combating COVID-19. Immune status is critical for evaluating the safety and response to the vaccine, however, the evolution of the immune response during immunization remains poorly understood.
View Article and Find Full Text PDFMil Med
July 2022
Medical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, San Diego, CA 92106, USA.
Introduction: Although retrospective analyses have found that combat-injured service members are at high risk for mental and physical health outcomes following injury, relatively little is known about the long-term health of injured service members. To better understand long-term health outcomes after combat injury, a large, prospective observational cohort collecting both subjective and objective health data is needed. Given that a study of this nature would be costly and face many logistical challenges, we first conducted a pilot to assess the feasibility of a larger, definitive study.
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