Oxidative stress and erythropoietin response in altitude exposure.

Purpose: Oxidative stress and erythropoietin (EPO) levels are increased following high altitude exposure. We hypothesized that the altitude-oxidative stress and EPO response would be associated with the presence or absence of acute mountain sickness (AMS) in subjects exposed at high altitude.

Methods: The study enrolled 29 healthy volunteers exposed at altitudes without strenuous physical exercise.

Gene transfer into human keloid tissue with adeno-associated virus vector.

BACKGROUND Gene transfer is a new territory for clinicians. Intractable disorders might be approached in such a way. Adeno-associated virus (AAV) vector has been transfected successfully into a variety of tissues including skin.