2 results match your criteria: "National University Hospital Medical Centre[Affiliation]"

Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban.

Drug Metab Dispos

November 2019

Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore (E.J.Y.C., D.W.X.T., D.X.Y.C., E.C.Y.C.); and National University Cancer Institute, National University Hospital Medical Centre, Singapore, Singapore (E.C.Y.C.)

Rivaroxaban is indicated for stroke prevention in nonvalvular atrial fibrillation (AF). Its elimination is mediated by both hepatic metabolism and renal excretion. Consequently, its clearance is susceptible to both intrinsic (pathophysiological) and extrinsic (concomitant drugs) variabilities that in turn implicate bleeding risks.

View Article and Find Full Text PDF

Body fluids are often used as specimens for medical diagnosis. With the advent of advanced analytical techniques in biotechnology, the diagnostic potential of saliva has been the focus of many studies. We recently reported the presence of excess salivary sugars, in patients with Alzheimer's disease (AD).

View Article and Find Full Text PDF