15 results match your criteria: "National University Hospital Center[Affiliation]"

Introduction: Despite the increasing trend of utilizing robotic techniques in pyeloplasty, little is known about the learning curve for robot-assisted pyeloplasty (RAP) amongst urologists with no prior robotic experience. Therefore, the present study aimed to evaluate the learning curve of residents in the last year or recently appointed urologists performing RAP using an ex-vivo model.

Methods: A prospective ex-vivo model study was conducted including participants who were either residents in the last year or recently appointed urologists.

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Article Synopsis
  • The study analyzed global, regional, and national trends in injury burden and identified risk factors contributing to injuries using data from the GBD 2019.
  • In 2019, there were approximately 713.9 million injury incidents and 4.3 million injury-related deaths globally, with low bone mineral density emerging as the leading risk factor.
  • The findings emphasize the need for effective global injury prevention policies by highlighting the persistent impact of injuries on global health.
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Regulatory T cell homing and activation is a signature of neonatal sepsis.

Front Immunol

July 2024

Paris-City University, Mére et Enfants en Milieu Tropical: pathogénes, systéme de santé et transition épidémiologique (MERIT), Institute of Research for Development (IRD), Paris, France.

Article Synopsis
  • Regulatory T cells (Treg) are crucial for managing immune responses in newborns, especially regarding tolerance to maternal antigens and fighting infections at birth.
  • This study, focusing on newborns in West Africa, found that neonates with early-onset sepsis (EOS) had reduced Treg frequency and expression of the Foxp3 marker compared to healthy newborns with prenatal risk factors, indicating a compromised immune profile.
  • The findings suggest that specific Treg markers like CTLA-4, PD-1, and CD39 could serve as potential early diagnostic indicators for EOS, as their expression correlates with the severity and outcome of the condition.
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Article Synopsis
  • Cholera, caused by the bacteria Vibrio cholera, poses a significant public health risk in Africa; this study aimed to examine pathogenic Vibrionaceae in human stool and environmental water samples from Saint-Louis, Senegal.
  • A hospital-based study from 2013 to 2015 involved collecting stool samples and conducting monthly water testing to identify Vibrio bacteria using PCR techniques.
  • The results showed no V. cholerae strains in patients' stool, but various Vibrio species, including toxigenic ones, were found in water, highlighting potential environmental risks for Vibriosis transmission in the region.*
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The eradication of neonatal Group B (GBS) infections, considered as a major public health priority, necessarily requires a mastery of the data on vaginal carriage in pregnant women. The aims of this study were to determine the prevalence of vaginal carriage of GBS in pregnant women, antibiotic susceptibility, and associated risk factors. This was a cross-sectional, descriptive study conducted over a period of 9 months (July 2020 to March 2021) in pregnant women between 34 and 38 weeks of gestation (WG) followed at the Nabil Choucair health center in Dakar.

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Hepatitis B in Africa Collaborative Network: cohort profile and analysis of baseline data.

Epidemiol Infect

April 2023

Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Approximately 80 million people live with chronic hepatitis B virus (HBV) infection in the WHO Africa Region. The natural history of HBV infection in this population is poorly characterised, and may differ from patterns observed elsewhere due to differences in prevailing genotypes, environmental exposures, co-infections, and host genetics. Existing research is largely drawn from small, single-centre cohorts, with limited follow-up time.

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Few biomarkers for sepsis diagnosis are commonly used in neonatal sepsis. While the role of host response is increasingly recognized in sepsis pathogenesis and prognosis, there is a need for evaluating new biomarkers targeting host response in regions where sepsis burden is high and medico-economic resources are scarce. The objective of the study is to evaluate diagnostic and prognostic accuracy of biomarkers of neonatal sepsis in Sub Saharan Africa.

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Background: Liquid discharges from hospitals (effluents) threaten the environment and are now a central concern of all stakeholders in the health system and those in the protection of the environment. The management of effluents is a major problem in developing countries. The objective of this study was to assess the quality of effluent management at the level of university hospital centers (CHU) in the Littoral region in Benin.

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Background: In 2015, the Army Teaching Hospital-University Teaching Hospital (HIA-CHU []) laboratory in Benin launched a quality improvement programme in alignment with the World Health Organization Regional Office for Africa's Stepwise Laboratory Improvement Process Towards Accreditation (SLIPTA). Among the sub-Saharan African laboratories that have used SLIPTA, few have been francophone countries, and fewer have belonged to a military health system. The purpose of this article was to outline the strategy, implementation, outcomes and military-specific challenges of the HIA-CHU laboratory quality improvement programme from 2015 to 2018.

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One of the main manifestations of Sturge Weber syndrome is seizures. We report the case of a child received in the context of generalized seizures and in whom a cerebral contrast CT was sufficient to make the diagnosis of Sturge Weber syndrome.

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Purpose: Microspheres are effective embolic agents, especially for the management of bleeding and oncologic lesions. The first FairEmbo study reported the effectiveness of embolization using suture fragments. The effectiveness and safety of arterial embolization with suture-based microparticles (SBM) were assessed in a swine model.

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Introduction: Neonatal sepsis outreaches all causes of neonatal mortality worldwide and remains a major societal burden in low and middle income countries. In addition to limited resources, endemic morbidities, such as malaria and prematurity, predispose neonates and infants to invasive infection by altering neonatal immune response to pathogens. Nevertheless, thoughtful epidemiological, diagnostic and immunological evaluation of neonatal sepsis and the impact of gestational malaria have never been performed.

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Hemostatic embolization of renal artery pseudoaneurysm using absorbable surgical suture (FairEmbo concept).

Diagn Interv Imaging

November 2020

Interventional Radiology Section, Department of Medical Imaging, University Hospital Timone, AP-HM, 13005 Marseille, France; Cerimed, Aix Marseille University, 13005 Marseille, France.

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Morphology of the lateral fossa of the brain (sylvian valley): anatomo-radiological aspects and surgical application.

Surg Radiol Anat

June 2019

Laboratory of Anatomy and Organogenesis, Faculty of Medicine, Pharmacy and Stomatology, Cheikh Anta Diop University, Post Box 5885, 10700, Dakar, Senegal.

Introduction: The knowledge acquired on the lateral fossa of the brain (LFB) is heterogeneous and incomplete. Our goal was to provide a morphological description of the LFB and analyze the impact of these descriptions on the surgical approach of the region.

Methods: The morphology of LFB was studied on 40 cerebral hemispheres of 20 right-handed subjects aged 18-55 years with an MRI of 1.

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