643 results match your criteria: "National Taiwan University Hospital Yun-Lin Branch[Affiliation]"

Background: Accurate pain assessment is essential in the emergency department (ED) triage process. Overestimation of pain intensity, however, can lead to unnecessary overtriage. The study aimed to investigate the influence of pain on patient outcomes and how pain intensity modulates the triage's predictive capabilities on these outcomes.

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Background: Acute appendicitis is one of the most common abdominal emergencies, with management approaches that vary depending on the available resources and setting. However, there is a lack of studies on the differences of surgical outcomes and quality of care between tertiary care hospitals and regional hospitals.

Methods: This multicenter retrospective study included 2158 consecutive adult patients between January 2014 and June 2018 at three hospitals.

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Effect of crew ratio of advanced life support-trained personnel on patients with out-of-hospital cardiac arrest: A systematic review and meta-analysis.

J Formos Med Assoc

May 2024

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Emergency Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan.

Background/purpose: This review aimed to investigate the effect of crew ratios of on-scene advanced life support (ALS)-trained personnel on patients with out-of-hospital cardiac arrest (OHCA).

Methods: We systematically searched PubMed, Ovid EMBASE, and the Cochrane Central Register of Controlled Trials databases from the inception date until September 30, 2022, for eligible studies. Two reviewers independently screened the studies for relevance, extracted data, and quality.

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Aims: To investigate the musculoskeletal morphomechanical properties (i.e., the thickness and elastic modulus) and the total count of power Doppler signals near the sacroiliac joints in patients with ankylosing spondylitis (AS) and non-AS individuals.

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Spinal cord compression as the first manifestation of metastatic malignancies: A retrospective study of surgical outcomes from a single institution.

Asian J Surg

August 2024

Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei City, Taiwan; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yun-Lin Branch, Yunlin County, Taiwan; Spine Tumor Center, National Taiwan University Hospital, Taipei City, Taiwan. Electronic address:

Background: Given the limited studies addressing the issue about the effect of different surgical modalities for metastatic spinal cord compression (MSCC) as the first malignancy manifestation, we conducted a retrospective case-control study to evaluate the surgical outcome of MSCC as the first malignancy manifestation.

Methods: A total of 128 patients who were suspected of having metastatic spinal cord compression and underwent surgery from 2008 to 2021 were enrolled in the study. All patients were categorized into either 'debulking group' or 'palliative group'.

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Use of the CHADS-VASc score to predict subsequent myocardial infarction in atrial fibrillation.

Hellenic J Cardiol

July 2024

Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, 100, Taiwan, ROC; Cardiovascular Center, National Taiwan University Hospital, Taipei, Taiwan, ROC. Electronic address:

Background: The risk of subsequent myocardial infarction (MI) varies widely in patients with atrial fibrillation (AF). No convenient scoring system currently exists to identify MI in AF. While each element of the CHA2DS2-VASc (congestive heart failure; hypertension; age ≥75 years [doubled]; type 2 diabetes; previous stroke or thromboembolism [doubled]; vascular disease; age 65-75 years; and sex category) score can increase the likelihood of MI, this retrospective longitudinal study aimed to determine the accuracy of the CHA2DS2-VASc score in predicting subsequent MI risk in AF.

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Background/purpose: Efforts were made to explore the influence of diagnostic timing for cancer-associated thromboembolic events on survival of ovarian cancer patients.

Methods: We reviewed the medical records of 75 ovarian cancer patients with thromboembolism and evaluated the prognostic factors affecting disease-free survival and overall survival.

Results: These 75 patients were classified into two categories by the diagnostic timing of the thromboembolism, during (33 cases) and after (42 cases) initial diagnosis of ovarian cancer groups.

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Background: Atrial fibrillation (AF) has been linked to increased hyperthyroidism risk, but contributing factors are unclear.

Objective: We aimed to investigate whether AF could predict hyperthyroidism and related risk factors.

Methods: This retrospective cohort study was conducted in a tertiary medical institution and included patients aged 18 years or older with AF but without hyperthyroidism at diagnosis.

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Article Synopsis
  • The study investigates effective treatment strategies for carotid blowout syndrome in patients with complications such as tumor invasion or necrosis affecting the external carotid artery (ECA) and potentially the internal carotid artery (ICA) or common carotid artery (CCA).
  • A total of 110 patients were grouped based on the extent of arterial invasion and the type of therapeutic embolization received, with analyses conducted to assess risks of recurrent bleeding.
  • Results indicated that patients with simultaneous ICA/CCA invasion had a significantly higher recurrence risk after ECA embolization alone compared to those receiving more extensive treatment, particularly when air-containing necrosis was present near the ICA/CCA.
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Background: Expression of immune checkpoints in the tumor microenvironment is one mechanism underlying paclitaxel (PTX) chemoresistance. This study aimed to investigate whether the addition of checkpoint blockade to PTX can improve the therapeutic efficacy against apparently disseminated intraperitoneal tumors.

Methods: We analyzed the in vivo expression of various immune checkpoints in CD3CD8 cytotoxic T cells from tumor-bearing mice treated with or without PTX and validated the tumor-killing activities of selected checkpoint-expressing T-cell subpopulations ex vivo.

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Article Synopsis
  • * The research involved 6,768 participants who underwent urine tests, with detailed analysis of over 3.6 million SNPs to find correlations with urine albumin levels.
  • * Six key genetic loci were identified, including FCRL3 and PIEZO2, which may influence kidney health and the development of albuminuria in the study group.
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Article Synopsis
  • The study aimed to evaluate how well emergency medical technicians can recognize agonal respiration under varying mobile network conditions while watching videos.
  • Five EMTs viewed 30 videos with different resolutions and frame rates, reporting the breathing patterns of patients and the time taken to identify them.
  • Results showed a high overall recognition accuracy of 80.7%, with frame rate impacting the speed of recognizing agonal respiration significantly more than video resolution.
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Objective: In patients with atrial fibrillation (AF) and end-stage renal disease (ESRD), oral anticoagulants are contraindicated, and left atrial appendage occlusion (LAAO) is an alternative treatment. However, the efficacy of thromboembolic prevention using LAAO in these patients has rarely been reported in Asian populations. To our knowledge, this is the first long-term LAAO study in patients with AF undergoing dialysis in Asia.

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Article Synopsis
  • - This study analyzed the effectiveness of minimally invasive surgery (MIS) versus open surgery for treating high-risk endometrial cancer, including patients from Korea and Taiwan.
  • - After comparing outcomes in a matched sample of 284 patients, results showed no significant difference in disease-free or overall survival rates between the two surgical approaches.
  • - The study concluded that MIS is just as effective as open surgery in maintaining survival rates for endometrial cancer patients at high risk of recurrence.
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Using 3-stage pooled-plasma hepatitis C virus (HCV) RNA testing performed quarterly among at-risk people with human immunodeficiency virus (PWH), we found that if testing had been performed every 6 or 12 months, 58.6%-91.7% of PWH who recently acquired HCV would be delayed for diagnosis and might contribute to onward HCV transmission with longer durations.

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Purpose: To investigate the survival outcomes of metastatic castration-resistant prostate cancer (mCRPC) patients receiving first-line novel androgen receptor axis-targeted therapies (ARATs) and prognostic factors for patient survival.

Methods: This retrospective study obtained data from 202 patients who started abiraterone acetate or enzalutamide as first-line therapy for mCRPC between 2016 and 2021 from a single academic center. The primary endpoint was overall survival (OS) defined as the interval from the start of ARAT to death, loss to follow-up, or the end of the study period.

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Article Synopsis
  • * Researchers analyzed a group of adult patients with either dense fine speckled (DFS) or homogeneous ANA test patterns, finding that the DFS group had a significantly lower prevalence of AARD compared to the homogeneous group.
  • * The results indicated that while a DFS pattern is associated with a lower prevalence of AARD, it does not guarantee that a patient is free of common autoantibodies, highlighting the need for further testing for accurate diagnosis.
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Treatment of primary aldosteronism: Clinical practice guidelines of the Taiwan Society of Aldosteronism.

J Formos Med Assoc

March 2024

Taiwan Primary Aldosteronism Investigation (TAIPAI) Study Group, Taipei, 100225, Taiwan.

Primary aldosteronism (PA) is the most common cause of secondary hypertension and one of the few medical diseases that can be cured by surgery. Excessive aldosterone secretion is highly associated with cardiovascular complications. Many studies have shown that patients with unilateral PA treated with surgery have better survival, cardiovascular, clinical, and biochemical outcomes than those who receive medical treatment.

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How should anti-hypertensive medications be adjusted before screening for primary aldosteronism?

J Formos Med Assoc

March 2024

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Anti-hypertensive medications may affect plasma renin activity and/or plasma aldosterone concentration, misleading the interpretation of the aldosterone-to-renin ratio when screening for primary aldosteronism. The Task Force of Taiwan PA recommends that, when necessary, using α-adrenergic receptor blocking agents, centrally acting α-adrenergic agonists, and/or non-dihydropyridine calcium channel blockers should be considered to control blood pressure before screening for PA. We recommend temporarily holding β-adrenergic receptor blocking agents, mineralocorticoid receptor antagonists, dihydropyridine calcium channel blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and all diuretics before screening for PA.

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Background: Osteoporosis is a common metabolic bone disease that benefits from many newly developed anti-osteoporosis medications (AOMs). Reimbursement policies need to allocate medical budgets properly based on evidence-based data. This study aimed to investigate the 11-year secular trend, focusing on older age and males in this adjustment wave of the National Health Insurance reimbursement.

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Background: The Bureau of National Health Insurance in Taiwan implemented a new reimbursement scheme incorporating bone mineral density (BMD) criteria on Jan. 1, 2011. This study aimed to investigate a real-life 11-year secular trend of adherence in new AOMs users and evaluated the change of adherence to AOMs therapy in different urbanization areas after reimbursement criteria were restrained.

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Background Atrial fibrillation (AF) is associated with increasing risk of thromboembolic or ischemic stroke. The CHADS-VASc score is a well-established predictor of AF stroke. Patients with AF have an increased risk of stroke if they have diabetes.

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Effect of using G-FAST to recognize emergent large vessel occlusion: A city-wide community experience.

J Formos Med Assoc

October 2023

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Emergency Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan.

Article Synopsis
  • This study evaluated a prehospital bypass strategy for large vessel occlusion strokes using the G-FAST test to improve patient outcomes in a metropolitan area.
  • It compared two groups of stroke patients: one before the intervention (802 patients) and one during the intervention using G-FAST (695 patients), focusing on rates of endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT).
  • Results indicated that the intervention group had significantly higher rates of EVT and IVT, although they experienced longer prehospital and hospital times overall, suggesting that the bypass strategy is beneficial for stroke patients.
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