2,218 results match your criteria: "National Taipei University of Nursing and Health[Affiliation]"

Impact of COVID-19 Pandemic on the Prevalence of Metabolic Syndrome in Health Care Workers: A Cohort Study at a Designated COVID-19 Hospital in Taiwan.

J Occup Environ Med

January 2025

From the Department of Family Medicine, Taipei City Hospital, Heping Fuyou Branch, Taipei, Taiwan (C.H., M.-J.C.); Section of Infectious Diseases, Taipei City Hospital, Heping Fuyou Branch, Taipei, Taiwan (Y.-F.Y.); Department of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan (Y.-F.Y., M.-J.C., C.-C.C.); Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Y.-F.Y., M.-J.C.); Institute of Public Health, National Yang Ming Chiao Tung University, Taipei, Taiwan (Y.-F.Y., Y.-C.C.); University of Taipei, Taipei, Taiwan (Y.-F.Y., Y.-C.C.); and Department of Education and Research, Taipei City Hospital, Taipei, Taiwan (Y.-F.Y., Y.-C.C.).

Objectives: This cohort study aimed to determine the effect of the COVID-19 pandemic on the prevalence of metabolic syndrome (MetS) among health care workers at a dedicated COVID-19 hospital in Taiwan.

Methods: This study recruited 397 health care workers who completed health checkups before and during the COVID-19 pandemic. The differences of MetS and its components prevalence before and during the COVID-19 pandemic were compared using the paired samples t tests for normally distributed variables, and Wilcoxon signed-rank tests for nonnormally distributed variables.

View Article and Find Full Text PDF

Background: Death is a natural part of life that no one can avoid. Listening to patients and supporting their needs during the dying process is crucial. However, dying patients are often not given a voice or choices regarding their care plans.

View Article and Find Full Text PDF

Wharton's jelly of the umbilical cord serves as a natural biomaterial to promote osteogenesis.

Biomater Sci

December 2024

Division of Joint Reconstruction, Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China.

Various factors can contribute to bone damage or loss, presenting challenges for bone regeneration. Our study explores the potential clinical applications of two processed forms of Wharton's jelly of the human umbilical cord for treating bone loss. Wharton's jelly from fresh umbilical cords underwent two distinct processes: (1) frozen Wharton's jelly (WJF), preserved with cryoprotective agents, and (2) decellularized Wharton's jelly matrix (WJD), prepared only lyophilization without cryoprotectants.

View Article and Find Full Text PDF

Background: Survival following an out-of-hospital cardiac arrest depends on prompt defibrillation. Despite the efforts made to install automated external defibrillators (AEDs) in crowded areas, their usage rate remains suboptimal. This study evaluated the efficiency of installing AEDs at key landmarks in Taoyuan City to enhance accessibility and usage.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates how linguistic features in speech can help identify early cognitive impairments in Alzheimer's disease (AD), as previous research has shown their potential sensitivity to detecting the condition.
  • By analyzing connected speech from 80 participants, grouped into early-AD and normal controls, the study examined 15 linguistic features alongside neuropsychological tests and imaging results.
  • The results indicated significant differences in speech characteristics between the groups, with machine learning techniques achieving up to 88% accuracy in detection, emphasizing the importance of features like mean length of utterance and long pauses in improving predictive accuracy alongside biomarkers.
View Article and Find Full Text PDF

Implementation of newborn screening for mucopolysaccharidosis type IVA and long-term monitoring in Taiwan.

Genet Med

December 2024

Department of Pediatrics, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan; The Rare Disease Center, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; Department of Infant and Child Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. Electronic address:

Article Synopsis
  • Mucopolysaccharidosis IVA (MPS IVA) is a rare genetic disorder caused by a deficiency in an enzyme called N-acetylgalactosamine-6-sulfatase (GALNS).
  • Between September 2019 and October 2023, newborn screening for MPS IVA in Taiwan involved 264,843 infants, revealing a confirmed incidence of 3.4 cases per 100,000 live births.
  • The screening identified nine confirmed cases, with an additional 18 suspected cases and 61 heterozygotes, highlighting the importance of early diagnosis and enzyme replacement therapy to improve health outcomes.*
View Article and Find Full Text PDF

In vitro drug testing using patient-derived ovarian cancer organoids.

J Ovarian Res

October 2024

Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.

Article Synopsis
  • * Patient-derived organoids (PDOs) were created from fresh ovarian cancer tumors to explore their drug responses and how these might relate to actual patient outcomes.
  • * The study successfully established 31 PDOs that maintained characteristics of the original tumors, and testing revealed significant variation in drug sensitivity among these organoids, highlighting the potential for personalized treatment approaches.
View Article and Find Full Text PDF

Background And Objectives: The aim of this study was to investigate the effects of 12-week somatosensory games on heart rate variability and sleep-related biomarkers in middle-aged women with poor sleep quality.

Research Design And Methods: Twenty-nine women with poor sleep quality were recruited as participants randomly assigned into ring fit adventure exergame group (RFA,  = 15) and control group (CON,  = 14). The RFA group received ring fit adventure exergame for 60 min each time, 2 times a week, for 12 weeks.

View Article and Find Full Text PDF

Healthcare systems must embody equity, diversity, and inclusion (EDI) and, in the event of unfairness, appropriate policies / countermeasures should be enacted. The healthcare system response to the COVID-19 pandemic not only highlighted how socioeconomic disparities affect mortality risk but also posed significant challenges to the successful practice of EDI in healthcare. In light of this, this article was written to provide an overview of EDI, analyze the international efforts to promote it, and suggest strategies for promoting EDI in infectious disease healthcare using COVID-19 as an example.

View Article and Find Full Text PDF

Background: Concurrent with population ageing, falls have become a significantly more challenging public health issue among older adults. Three years of data collected recently from a nursing home in northern Taiwan reveals an increasing trend in fall density that is primarily associated with aging, physiological decline, chronic diseases, polypharmacy, osteoporosis, and lack of exercise. The percentage of nursing home residents at high risk of falls is currently at 12.

View Article and Find Full Text PDF

[Improving the Accuracy of Patient Self-Care After Joint Replacement Surgery].

Hu Li Za Zhi

October 2024

MSN, RN, Director, Department of Nursing, New Taipei City Municipal Tu Cheng Hospital (Build and Operated by Chang Gung Medical Foundation), and Adjunct Lecturer, Department of Nursing, Chang Gung University of Science and Technology, Taiwan, ROC.

Background & Problems: Joint replacement wound stitches are typically not removed until two weeks after the operation. Therefore, patients with joint replacement must be able to execute proper wound care after discharge from the hospital to reduce the risk of wound infection. Prior data from Chang Gung Memorial Hospital's orthopedics ward indicate only 69% of joint-replacement patients are able to perform wound care properly at home.

View Article and Find Full Text PDF

A population-based study on the associations of thyroid cancer with chronic periodontitis.

J Periodontol

September 2024

Research Center of Data Science on Healthcare Industry, College of Management, Taipei Medical University, Taipei, Taiwan.

Article Synopsis
  • A population-based case-control study in Taiwan investigated the relationship between chronic periodontitis and thyroid cancer using data from the Longitudinal Health Insurance Database 2010, involving 2,775 thyroid cancer patients and 8,325 matched controls.
  • The results showed a significant higher prevalence of chronic periodontitis in thyroid cancer patients (38.5%) compared to controls (24.1%), with an odds ratio indicating nearly double the risk of chronic periodontitis among those with thyroid cancer.
  • The findings suggest that chronic periodontitis may be a potential risk factor for developing thyroid cancer, highlighting the need for better oral health monitoring and preventive measures.
View Article and Find Full Text PDF

Background/objectives: Brain tumor patients confront numerous challenges arising from diagnosis and treatment, and these impact the patient's physical, mental, and social functions at all levels. Primary informal caregivers assume a pivotal role in home-based patient care. Of particular importance are the coping strategies employed by family caregivers, as they can influence both their own health and the overall quality of home care.

View Article and Find Full Text PDF

Comment on: "Premature Death in Bodybuilders: What Do We Know?".

Sports Med

December 2024

Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Medical University Hospital, Taipei City, Taiwan.

View Article and Find Full Text PDF

Background And Aim: With the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has become a public health concern, but its progression mechanism remains unclear. Experimental models mimicking human NAFLD/steatohepatitis (NASH) are crucial. This study simulates gut microbiota imbalance effects on NASH and liver fibrosis.

View Article and Find Full Text PDF
Article Synopsis
  • A study in Taiwan analyzed predictors of both COVID-19-specific and non-COVID-19-specific deaths among 2,196 hospitalized patients infected with SARS-CoV-2 between January and July 2022.
  • Out of the 175 deceased patients, 84% died from causes directly related to COVID-19, while 16% had non-COVID-19-related deaths, revealing significant mortality risks associated with age and underlying health conditions.
  • Results indicated that individuals aged 65 and older faced a heightened risk for both types of death, while those who were fully vaccinated or received Paxlovid had lower risks for COVID-19-related deaths, highlighting the importance of vaccination and treatment in managing outcomes.
View Article and Find Full Text PDF

Objectives: Pharmacological and non-pharmacological interventions are mostly designed for patients with early Alzheimer's disease (AD) dementia. Long-term case management and planning for the remainder of life with disability require an estimation of the survival duration.

Methods: This cohort study utilized data from the National Health Insurance Research Database, Taiwan, to identify incident cases of mild-to-moderate AD dementia diagnosed from 2000 to 2002, followed through December 31, 2017.

View Article and Find Full Text PDF

Background: Candida is one of the common pathogens in nosocomial infections. Culture is the gold standard for diagnosing candidemia. is identified via the germ tube test, which uses serum as the culture medium, which is costly and time-consuming.

View Article and Find Full Text PDF

Background: Limited knowledge exists regarding the interrelations between sleep quality and resilience within the demographic of healthy, community-residing middle-aged and older adults, with a particular dearth of information regarding sex-specific associations. This study aimed to examine the sex-specific associations between sleep quality, resilience, and biomarkers in community-dwelling middle-aged and older adults.

Methods: This cross-sectional study was conducted using data from the 2022 Gan-Dau Healthy Longevity Plan survey initiated by the locality-based community hospital, Taipei Municipal Gan-Dau Hospital (TMGDH).

View Article and Find Full Text PDF

Background: Technological advancements have extended the lifespan of individuals with congenital heart disease (CHD), but physical and mental health issues can affect their life and job satisfaction.

Aims: This study examined whether grit can protect full-time employed adults with CHD from depression by exploring its mediating role between depressive symptoms and life or job satisfaction.

Methods: A cross-sectional design involved 181 adults with CHD assessed using the Patient Health Questionnaire, Grit-10, Satisfaction with Life Scale, and Basic Psychological Need Satisfaction at Work Scale.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates a novel method for monitoring labor pain using ECG waveform analysis and machine learning techniques based on uterine contractions.
  • Conducted at National Taiwan University Hospital with 6010 ECG samples collected from women, a Nociception Monitoring Index (NoM) was developed through various machine learning models.
  • The LightGBM model outperformed others with an AUC of 0.96 and 90% accuracy, indicating its potential for improving labor pain monitoring in healthcare settings.
View Article and Find Full Text PDF

Type 2 diabetes mellitus (T2DM) is a prevalent health challenge faced by countries worldwide. In this study, we propose a novel large language multimodal models (LLMMs) framework incorporating multimodal data from clinical notes and laboratory results for diabetes risk prediction. We collected five years of electronic health records (EHRs) dating from 2017 to 2021 from a Taiwan hospital database.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the cardiovascular safety of romosozumab, a treatment for osteoporosis in postmenopausal women, amid concerns over its potential cardiovascular risks.
  • A systematic review identified 25 randomized controlled trials involving almost 25,000 participants, concluding that romosozumab does not significantly increase cardiovascular mortality or major cardiovascular events compared to placebo.
  • The findings suggest that romosozumab may be a safer treatment option than previously thought, but more real-world data are needed to fully validate this safety profile.
View Article and Find Full Text PDF