689 results match your criteria: "National Research Nuclear University "Moscow Engineering Physics Institute"[Affiliation]"

The study of nuclei and antinuclei production has proven to be a powerful tool to investigate the formation mechanism of loosely bound states in high-energy hadronic collisions. The first measurement of the production of _{Λ}^{3}H in p-Pb collisions at sqrt[s_{NN}]=5.02  TeV is presented in this Letter.

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We have developed an original method to measure the temperature dependence of the biological tissue electrical properties based on its heating by homogeneous optical radiation.The conventional approach in hyperthermia research involves heating due to a thermal conductivity through the surface of the sample. The novel technique is based on the emission of heat sources in the sample volume caused by the absorption of optical radiation.

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The development of effective biomedical technologies using magnetic nanoparticles (MNPs) for the tasks of oncotherapy and nanodiagnostics requires the development and implementation of new methods for the analysis of micro- and nanoscale distributions of MNPs in the volume of cells and tissues. The paper presents a new approach to three-dimensional analysis of MNP distributions - scanning magnetic force nanotomography as applied to the study of tumor tissues. Correlative reconstruction of MNP distributions and nanostructure features of the studied tissues made it possible to quantitatively estimate the parameters of three-dimensional distributions of composite nanoparticles based on silicon and iron oxide obtained by femtosecond laser ablation and injected intravenously and intratumorally into tumor tissue samples of B16/F1 mouse melanoma.

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Properties of Daily Helium Fluxes.

Phys Rev Lett

June 2022

INFN TIFPA, 38123 Povo, Trento, Italy.

We present the precision measurement of 2824 daily helium fluxes in cosmic rays from May 20, 2011 to October 29, 2019 in the rigidity interval from 1.71 to 100 GV based on 7.6×10^{8} helium nuclei collected with the Alpha Magnetic Spectrometer (AMS) aboard the International Space Station.

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Pulsed laser deposition of nanostructured molybdenum sulfide films creates specific nonequilibrium growth conditions, which improve the electrocatalytic properties of the films in a hydrogen evolution reaction (HER). The enhanced catalytic performance of the amorphous a-MoS (2 ≤ ≤ 3) matrix is due to the synergistic effect of the Mo nanoparticles (Mo-NP) formed during the laser ablation of a MoS target. This work looks at the possibility of employing a-MoS/NP-Mo films (4 and 20 nm thickness) to produce hydrogen by photo-stimulated HER using a p-Si cathode.

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Singularities of the Poynting vector field subwavelength patterns in resonant light scattering by nanoparticles are discussed and classified. There are two generic types of the singularities, namely, (i) the singularities related to the vanishing of the magnetic (and/or electric) field at the singular points and (ii) the singularities related to the formation of standing waves in proximity to the singular points. The connection of these types of singularities to the topology of the singular points, space dimension (3D vs.

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Using a data sample of proton-proton collisions collected by the CMS experiment at the LHC in 2017 and 2018 with an integrated luminosity of , the and decays are observed with significances exceeding 5 standard deviations. The resulting branching fraction ratios, measured for the first time, correspond to and , where the last uncertainty in the first ratio is related to the uncertainty in the ratio of production cross sections of and mesons, .

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Hybrid multimodal nanoparticles, applicable simultaneously to the noninvasive imaging and therapeutic treatment, are highly demanded for clinical use. Here, Fe-Au core-satellite nanoparticles prepared by the method of pulsed laser ablation in liquids were evaluated as dual magnetic resonance imaging (MRI) and computed tomography (CT) contrast agents and as sensitizers for laser-induced hyperthermia of cancer cells. The biocompatibility of Fe-Au nanoparticles was improved by coating with polyacrylic acid, which provided excellent colloidal stability of nanoparticles with highly negative ζ-potential in water (-38 ± 7 mV) and retained hydrodynamic size (88 ± 20 nm) in a physiological environment.

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Surface-enhanced Raman scattering (SERS) spectroscopy is a surface- or cavity-enhanced variant of Raman scattering spectroscopy that allows the detection of analytes with a sensitivity down to single molecules. This method involves the use of SERS-active surfaces or cavities capable of concentrating incident radiation into small mode volumes containing the analyte. Here, we have engineered an ultranarrow metal-dielectric nano-cavity out of a film of the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) glycoprotein and a silver surface, held together by interaction between reduced protein sulfhydryl groups and silver.

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Liquid crystals self-assemble on nanopatterned alignment layers into purely soft matter metasurfaces sensitive to external stimuli and imparting tailored spatial modulations to transmitted light wavefronts. Upon fine optimization, they are capable of efficient light deflection by virtue of anomalous refraction into a dominating transmission diffraction order. To expand the spectral range and acquire additional functionality, we put forward the double-sided metasurface design based on the liquid crystal alignment by a pair of complementing patterned substrates.

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NIR-II J-Aggregated Pt(II)-Porphyrin-Based Phosphorescent Probe for Tumor-Hypoxia Imaging.

Adv Healthc Mater

August 2022

Department of Applied Biology and Chemical Technology and Research Institute for Smart Energy, The Hong Kong Polytechnic University (PolyU), Hung Hom, Kowloon, Hong Kong, 999077, P. R. China.

The luminescence of traditional phosphorescence-based hypoxia probes is limited to the visible and first near-infrared wavelength regions (<1000 nm), which has defects of higher light scattering and lower penetration depth in contrast with the second near-infrared wavelength window (NIR-II, 1000-1700 nm) for optical bioimaging. Herein, 5,15-bis(2,6-bis(dodecyloxy)phenyl)-porphyrin platinum(II) (PpyPt) with J-aggregation induced NIR-II phosphorescence is reported. J-aggregates of PpyPt are confirmed by the X-ray diffraction data in the crystalline state.

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The polarization of the Λ and Λ[over ¯] hyperons along the beam (z) direction, P_{z}, has been measured in Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV recorded with ALICE at the Large Hadron Collider (LHC). The main contribution to P_{z} comes from elliptic flow-induced vorticity and can be characterized by the second Fourier sine coefficient P_{z,s2}=⟨P_{z}sin(2φ-2Ψ_{2})⟩, where φ is the hyperon azimuthal emission angle and Ψ_{2} is the elliptic flow plane angle.

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Extracellular vesicles (EVs) are promising agents for liquid biopsy-a non-invasive approach for the diagnosis of cancer and evaluation of therapy response. However, EV potential is limited by the lack of sufficiently sensitive, time-, and cost-efficient methods for their registration. This research aimed at developing a highly sensitive and easy-to-use immunochromatographic tool based on magnetic nanoparticles for EV quantification.

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Facile Synthesis of Green Fluorescent Carbon Dots and Their Application to Fe Detection in Aqueous Solutions.

Nanomaterials (Basel)

April 2022

Center for Biomedical Optics and Photonics (CBOP) & College of Physics and Optoelectronic Engineering, Key Lab of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, Shenzhen University, Shenzhen 518060, China.

Carbon dots (CDs), a class of fluorescent nanomaterials, have attracted widespread attention from researchers. Because of their unique chemical properties, these high-quality fluorescent probes are widely used for ion and molecule detection. Excess intake of many ions or molecules can cause harm to the human body.

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Express and highly sensitive immunoassays for the quantitative registration of cardiac troponin I (cTnI) are in high demand for early point-of-care differential diagnosis of acute myocardial infarction. The selection of antibodies that feature rapid and tight binding with antigens is crucial for immunoassay rate and sensitivity. A method is presented for the selection of the most promising clones for advanced immunoassays via simultaneous characterization of interaction kinetics of different monoclonal antibodies (mAb) using a direct label-free method of multiplex spectral correlation interferometry.

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Quantum vortices are the quantized version of classical vortices. Their center is a phase singularity or vortex core around which the flow of particles as a whole circulates and is typical in superfluids, condensates and optical fields. However, the exploration of the motion of the phase singularities in coherently-coupled systems is still underway.

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Macrophage blockade using nature-inspired ferrihydrite for enhanced nanoparticle delivery to tumor.

Int J Pharm

June 2022

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 115409 Moscow, Russia; Department of Biomedical Engineering, Sechenov University, 119991 Moscow, Russia. Electronic address:

The rapid elimination of systemically administered drug nanocarriers by the mononuclear phagocyte system (MPS) compromises nanomedicine delivery efficacy. To mitigate this problem, an approach to block the MPS has been introduced and implemented by intravenous pre-administering blocker nanoparticles. The required large doses of blocker nanoparticles appeared to burden the MPS, raising toxicity concerns.

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Detection of low-volatile explosives in concentrations below 10 g/cm is a great challenge for portable ion mobility spectrometers (IMS) and field asymmetric IMS (FAIMS). We study the capabilities of FAIMS detector with ultraviolet laser ionization combined with organic additives (dopants) toluene and 1-methylnaphtalene to sense nitro-explosives: trinitrotoluene (TNT) and low-volatile cyclonite (RDX) and nitropentaerythritol (PETN). Differential mobility coefficients were measured for target ion peaks of TNT, RDX and PETN.

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Comparison of surface-passivation ability of the BAI salt and its induced 2D perovskite for high-performance inverted perovskite solar cells.

RSC Adv

July 2021

Center for Biomedical Optics and Photonics (CBOP), College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems, Shenzhen University Shenzhen 518060 P. R. China

Organic-inorganic lead halide perovskite solar cells have shown a rapid increase in power conversion efficiency (PCE) in the past decade. However, their performance still suffers from trap-assisted decline due to defects at the surface and grain boundaries in the polycrystalline active layer. In this study, a thin BAI layer was formed on the CHNHPbI surface, which was then transformed into either a two-dimensional (2D) perovskite layer (BAPbI) or the organic salt itself by controlling the post-annealing process.

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A search for low-mass dilepton resonances in Higgs boson decays is conducted in the four-lepton final state. The decay is assumed to proceed via a pair of beyond the standard model particles, or one such particle and a boson. The search uses proton-proton collision data collected with the CMS detector at the CERN LHC, corresponding to an integrated luminosity of 137 , at a center-of-mass energy .

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The study is focused on investigating approaches for assessing the texture shape deviation obtained by laser structuring by remelting (Waveshape). A number of metrics such as Fourier spectrum harmonic ratio, cross-correlation coefficient (reverse value), and spectral entropy are investigated in terms of surface-texture shape deviation estimation. The metrics are compared with each other by testing two hypotheses: determination of target-like shape of texture (closest to harmonic shape) and determination of texture presence on the cross-section.

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Atomically thin transition metal dichalcogenides (TMDCs) present a promising platform for numerous photonic applications due to excitonic spectral features, possibility to tune their constants by external gating, doping, or light, and mechanical stability. Utilization of such materials for sensing or optical modulation purposes would require a clever optical design, as by itself the 2D materials can offer only a small optical phase delay - consequence of the atomic thickness. To address this issue, we combine films of 2D semiconductors which exhibit excitonic lines with the Fabry-Perot resonators of the standard commercial SiO/Si substrate, in order to realize topological phase singularities in reflection.

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The spectra measurements of charged hadrons produced in the shower of a parton originating in the same hard scattering with a leptonically decaying Z boson are reported in lead-lead nuclei (Pb-Pb) and proton-proton (pp) collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV. Both Pb-Pb and pp data sets are recorded by the CMS experiment at the LHC and correspond to an integrated luminosity of 1.

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Modeling dipolar excitation for quadrupole mass filter.

Eur J Mass Spectrom (Chichester)

February 2022

Medchromteh, Ltd, Moscow, Russia.

The results of modeling AC and DC dipole excitation of ion oscillations in a quadrupole mass filter are presented. The simulation is done by numerical integration of the ion motion equations, ions' initial coordinates and velocities are distributed normally. For AC dipole excitation the instability bands on the (, stability diagram follow along the isolines and , creating regular dips on the transmission contour.

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