1,353 results match your criteria: "National Rehabilitation Center[Affiliation]"

Purpose: To investigate challenges with sexuality experienced by people with neuromuscular diseases and their needs for knowledge and guidance on sexual life to target future rehabilitation services.

Materials And Methods: 11 semi-structured individual interviews with 10 women and one man with neuromuscular diseases. The methodology was Interpretive Description, using the Crip Theory as the theoretical lens to guide the analysis.

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Purpose: Patients with refractory neurogenic bladder dysfunction may require urinary reconstruction due to severe incontinence, difficulty with catheterization, and to prevent upper urinary tract compromise. We evaluated long-term decisional regret and associated factors following urinary reconstruction in spinal cord injury patients.

Materials And Methods: We interviewed patients with spinal cord injuries who underwent bladder reconstruction surgery at least ten years ago, administering validated surveys on bowel quality of life and dysfunction, urinary tract infections, and decisional regret.

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We investigated the potential to improve motor learning and performance in people with multiple sclerosis (PwMS) with OPTIMAL theory conditions. OPTIMAL theory predicts that three main factors [i.e.

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Many medical conditions impair proprioception but there are few easy-to-deploy technologies for assessing proprioceptive deficits. Here, we developed a method-called "OpenPoint"-to quantify upper extremity (UE) proprioception using only a webcam as the sensor. OpenPoint automates a classic neurological test: the ability of a person to use one hand to point to a finger on their other hand with vision obscured.

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Article Synopsis
  • Artri King was an over-the-counter supplement aimed at treating joint pain, but the FDA warned it contained hidden ingredients like dexamethasone, which can pose health risks like adrenal insufficiency.
  • A study was conducted on patients who used the supplement and found significant health issues, including low cortisol levels and one case of new diabetes, prompting referrals to endocrinology.
  • The findings highlight the potential severe effects of such supplements, leading to recommendations for regular screening and careful monitoring of patients who use them.
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Objective: Vagus nerve stimulation (VNS) paired with rehabilitation therapy improved motor status compared to rehabilitation alone in the phase III VNS-REHAB stroke trial, but treatment response was variable and not associated with any clinical measures acquired at baseline, such as age or side of paresis. We hypothesized that neuroimaging measures would be associated with treatment-related gains, examining performance of regional injury measures versus global brain health measures in parallel with clinical measures.

Methods: Baseline magnetic resonance imaging (MRI) scans in the VNS-REHAB trial were used to derive regional injury measures (extent of injury to corticospinal tract, the primary regional measure; plus extent of injury to precentral gyrus and postcentral gyrus; lesion volume; and lesion topography) and global brain health measures (degree of white matter hyperintensities, the primary global brain measure; plus volumes of cerebrospinal fluid, cortical gray matter, white matter, each thalamus, and total brain).

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Ultrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors.

Ann Rehabil Med

December 2024

Department of Rehabilitation Medicine, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea.

Objective: Tremors are caused by contractions of reciprocally innervated muscles. The role of ultrasound in diagnosing tremors has not yet been investigated, although it appears to be promising because it can visualize muscle movements. In the present study, we report four cases of tremor (Holmes' tremor, extremity tremor associated with palatal myoclonus, dystonic tremor, and tremor associated with dystonia), which were evaluated using ultrasound and treated with botulinum toxin injections.

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Osteoporosis and osteopenia in young adults with spinal cord injury: The necessity of an early bone mineral density checkup.

J Spinal Cord Med

December 2024

Department of Physical Medicine and Rehabilitation, National Rehabilitation Center, Seoul, Republic of Korea.

To identify the prevalence and risk factors for low bone density (LBD) in young adults with spinal cord injury (SCI). Retrospective cross-sectional study. National Rehabilitation Center in Seoul, Korea.

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Article Synopsis
  • Metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease, and accurately diagnosing it in spinal cord injury (SCI) patients is crucial for prevention.
  • A study analyzed data from 2015 to 2019 to compare MetS prevalence in SCI patients versus the general population, finding that SCI patients had a significantly higher prevalence.
  • Factors like older age and lower income were linked to MetS in both groups, while lifestyle factors such as smoking and alcohol use were more significant in the general population, highlighting the need for tailored diagnostic criteria for SCI patients.
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Characteristics, intrapartum cardiotocography patterns, and postnatal brain imaging findings for cerebral palsy subtypes.

Am J Obstet Gynecol

December 2024

The Recurrence Prevention Committee, The Japan Obstetric Compensation System for Cerebral Palsy, Japan Council for Quality Health Care, Tokyo, Japan; Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, Mie, Japan.

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Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression.

Cell Stem Cell

December 2024

Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. Electronic address:

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Article Synopsis
  • The study investigates the effects of the COVID-19 pandemic on maternal, fetal, and infant mortality rates in South Korea using national statistics from 2012 to 2022.
  • It finds that while maternal deaths decreased overall, the maternal mortality rate fluctuated over the years, with an increase in 2020.
  • Despite a decline in the number of births and a reduction in maternal and infant deaths, mortality rates remained stable during the pandemic.
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Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel.

Sci Rep

November 2024

Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

Article Synopsis
  • Long-duration spaceflight can stress the skeletal and immune systems, but the specific response mechanisms are still not fully understood.
  • A study with mice on the ISS evaluated how different gravitational conditions (microgravity, lunar gravity, and Earth gravity) affected their bone, thymus, and spleen over 25-35 days.
  • Results showed that while bone density loss in microgravity was mostly restored in Earth gravity, lunar gravity only offered partial recovery; microgravity also caused thymus shrinkage, partially reversible by both lunar and Earth gravity but with ongoing gene expression issues.
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Cognitive models of reading assume that speech production occurs after visual and phonological processing of written words. This traditional view is at odds with more recent magnetoencephalography studies showing that the left posterior inferior frontal cortex (pIFC) classically associated with spoken production responds to print at 100-150 ms after word-onset, almost simultaneously with posterior brain regions for visual and phonological processing. Yet the theoretical significance of this fast neural response remains open to date.

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[Sincipital meningoencephaloceles: Clinical and surgical considerations].

Ann Chir Plast Esthet

November 2024

Service de chirurgie maxillo-faciale et plastique de la face, hôpital Purpan, CHU de Toulouse, place du Dr-Baylac, TSA 40031, 31059 Toulouse cedex 9, France.

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Objective: To determine the factors influencing the life satisfaction of people with physical disabilities during the COVID-19 pandemic, considering demographics, disability-related characteristics, health behaviors, and psychosocial characteristics.

Methods: We used cross-sectional data from 301 respondents of the 2021/2022 survey of the Korean Health Cohort Study for People with Physical Disabilities. Descriptive statistics were used to analyze the research subjects' characteristics, and chi-square tests and multiple logistic regression were used to identify the determinants of life satisfaction.

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The role of the extended amygdala and amygdala in mediating emotion and inhibitory control in native language versus second language processing is currently not well understood. The current study examined activity in the extended amygdala and amygdala when twelve healthy young adults were exposed to emotional-linguistic stimuli in either their native language (i.e.

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Virtual reality-based music attention training for acquired brain injury: A randomized crossover study.

Ann N Y Acad Sci

November 2024

Department of Rehabilitation Medicine, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Republic of Korea.

This single-blind randomized crossover study aimed to explore the effectiveness of virtual reality-based music attention training (VR-MAT) on cognitive function and examine its potential as a cognitive assessment tool in people with acquired brain injury (ABI). Overall, 24 participants with cognitive impairment secondary to a first-ever ABI underwent VR-MAT and conventional cognitive training (CCT) 3 months after onset. This was performed in two 4-week phases, over 8 weeks.

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Phonological knowledge plays a pivotal role in many aspects of language processing, but it remains controversial whether it is required for writing. In the present study, we examined the issue by focusing on written production in an opaque logographic script (kanji) with highly irregular pronunciation rules, which allowed for a rigorous test of whether or not phonology contributes to writing. Using a phonological priming paradigm in two experiments, we measured response latency while participants orally named target pictures or wrote down their names in kanji.

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Article Synopsis
  • The study evaluated the effectiveness of a 4-week treatment with Solifenacin and Trospium chloride for lower urinary tract symptoms (LUTS) in 206 stroke patients.
  • Results showed that both medications significantly improved urinary symptoms and quality of life compared to placebo, with Solifenacin showing better outcomes and fewer side effects.
  • The study highlights the importance of tailored treatments for LUTS in stroke patients, suggesting Solifenacin as a potentially safer and more effective option.
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Intravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series.

J Clin Med

October 2024

Department of Neural Regenerative Medicine, Institute of Regenerative Medicine, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.

Article Synopsis
  • * Seven patients received autologous MSCs without any serious side effects, showing no tumors or neurological decline throughout the process.
  • * Notable functional improvements and enhanced quality of life were reported 90 and 180 days after the infusion, indicating that this treatment could be beneficial for chronic SCI, though further large-scale studies are required for conclusive results.
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OnabotulinumtoxinA (onabotA) is approved in the US for 12 therapeutic indications. Real-world data on onabotA multi-indication use are limited, often leading to delayed or reduced treatment. This study provides real-world evidence on the safety of onabotA when treating multiple indications concomitantly.

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Terrestrial animals not only need to walk and run but also lie prone to rest and then stand up. Sit-to-stand (STS) and sit-to-walk (STW) transitions are vital behaviours little studied in species other than humans so far, but likely impose biomechanical constraints on limb design because they involve near-maximal excursions of limb joints that should require large length changes and force production from muscles. By integrating data from experiments into musculoskeletal simulations, we analysed joint motions, ground reaction forces, and muscle dynamics during STS and STW in a large terrestrial, bipedal and cursorial bird: the emu (Dromaius novaehollandiae; body mass ∼30 kg).

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Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests, and comorbidities. A minimally invasive, clinically scalable, and cost-effective way to directly measure cerebral blood flow presents an opportunity.

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