1 results match your criteria: "National Reference Center for Wilson Disease and Other Rare Copper Related Diseases[Affiliation]"
Epidemiology and economic burden of Wilson disease in France: A nationwide population-based study.
J Inherit Metab Dis
January 2025
National Reference Center for Wilson Disease and Other Rare Copper Related Diseases, Hôpital Fondation Adolphe de Rothschild, Paris, France.
Article Synopsis
- Wilson disease (WD) is a rare genetic disorder affecting copper metabolism, leading to copper buildup in the liver and brain, analyzed using data from the French national health database between 2010 and 2019.
- The study identified 2287 patients with a prevalence rate of 1 in 33,898 individuals; most patients were around 40 years old and exhibited significant morbidity with 44.2% having liver issues, 33.0% neurological symptoms, and 18.1% psychiatric problems.
- The research highlights the substantial healthcare costs associated with WD, averaging 4273.7€ per patient annually for hospitalization and significant sick leave expenses, indicating a considerable economic burden on affected individuals and the healthcare system.