2 results match your criteria: "National Reference Center for Perinatal Hemobiology[Affiliation]"
Severe neonatal thrombocytopenia due to anti-HPA-4b alloantibodies: Third report described in a Caucasian mother.
Transfusion
June 2024
Hospital Saint-Antoine, National Reference Center for Perinatal Hemobiology, Paris, France.
Article Synopsis
- * Genetic testing revealed an incompatibility in the HPA-4 system between the mother, father, and newborn, with confirmation of anti-HPA-4b antibodies indicating FNAIT.
- * This case highlights the importance of genetic testing for HPA alleles in diverse populations and suggests a need for matching maternal serum with paternal platelets in suspected cases to improve
Prenatal management of fetal anemia due to pyruvate kinase deficiency: A case report.
Transfusion
January 2023
Department of Fetal Medicine, Armand Trousseau Hospital, Paris, France.
Article Synopsis
- Pyruvate Kinase (PK) deficiency is a common enzyme defect that leads to congenital hemolytic anemia, often evident from birth.
- A family with a history of PK deficiency underwent prenatal management for their third child after previous complications from the condition; ultrasound monitoring helped identify severe fetal anemia, resulting in two intrauterine red blood cell transfusions.
- Successful treatment allowed the third child to be born healthy, emphasizing the importance of fetal monitoring and management in families with a diagnosed proband for PK deficiency.