1 results match your criteria: "National Key Clinical Department of Key Discipline of Neurology[Affiliation]"
Network Pharmacology Prediction and Experimental Verification for Anti-Ferroptosis of Edaravone After Experimental Intracerebral Hemorrhage.
Mol Neurobiol
July 2023
Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department of Key Discipline of Neurology, Southern China International Cooperation Base for Early Intervention and Functional Rehabilitation of Neurological Diseases, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Article Synopsis
- * A study using rats showed that Eda improved sensorimotor functions and reduced markers of ferroptosis, while in vitro tests demonstrated its ability to lessen mitochondrial damage and decrease oxidative stress.
- * The protective effects of Eda against ICH were linked to its ability to suppress the MEK/ERK signaling pathway and regulate proteins associated with ferroptosis, indicating its potential as a therapeutic strategy.