Sustainable improvement of granite sludge dust properties using microbially induced carbonate precipitation (MICP): strength enhancement, erosion prevention, and dust mitigation.

Granite sludge dust (GSD), a significant byproduct of granite processing globally, poses severe environmental and public health challenges, with India alone generating 200 million tons annually. The conventional use of GSD in soil stabilization and construction materials is limited to 20-30%, underscoring the urgent need for sustainable repurposing solutions within the circular economy catering to broader bulk utilization. Unlike traditional techniques, repurposing granite dust using microbially induced calcite precipitation (MICP) offers a sustainable low-impact and eco-friendly ground improvement solution.

What comes next: the fate of germa-, stanna-, and plumba--dodecaborate based electrolytes in calcium ion batteries.

Recent investigations on plumba- and stanna--dodecaborate-based electrolytes for alkali metal-ion batteries have demonstrated improved ionic conductivities at elevated temperatures. However, the potential of germa, stanna, and plumba borane in divalent ion batteries is uncertain. To address this knowledge gap, a theoretical approach has been adopted to explore the potential of Ge-, Sn-, and Pb-based borane anions as electrolytes for CIBs.

A coumarin and 1,8-napthyridine conjugated novel molecular hybrid: Synthesis, DFT insights and unveiling the selective fluorescent sensing of Hg ions with live-cell imaging application.

Herein, we have used a simple synthetic strategy to access a novel non-sulfur fluorescent molecular probe coumarin and 1,8-napthyridine conjugated probe DNCS. The developed probe has great selectivity and sensitivity for detecting Hg ions. Our photophysical properties evaluation for the synthesized probe with different metal ions (Ba, Al, Ca, Bi, Ce, Cd, Cu, Sr, Co, Fe, Cr, Fe, Mn, Hg, Zn, Pb, Ni, and Sn) unveiled the very selective and sensitive fluorescence sensing behavior with Hg ions in the energy window of near UV and visible light radiation in an organic aqueous solvent mixture (EtOH and water).

One-Pot Aminomethylation of Heteroarenes by Rongalite as C1 Source.

Rongalite-mediated one-pot aminomethylation of heteroarenes using secondary amines/anilines has been developed. This transition-metal-free and mild reaction offers an efficient way to synthesize aminomethylated heteroaromatic compounds with high yields and broad functional group tolerance. Here, Rongalite plays a key role in generating the C1 unit source , which triggers the aminomethylation process.

Rongalite as a Methylene Surrogate: Synthesis of Heterodiarylmethanes C(sp)-H Functionalization.

An efficient method for the synthesis of heterodiarylmethanes through the coupling of imidazo[1,2-]pyridines and heteroarenes using indoles employing rongalite as a methylenating reagent has been developed. This regioselective C-H functionalization provides a wide range of heterodiarylmethanes of imidazo[1,2-]pyridines and imidazo[2,1-]thiazole. Here, rongalite plays a crucial role in generating a C1 unit in situ, which triggers the heterodiarylmethylation process.

A TOPSIS based multi-objective optimal deployment of solar PV and BESS units in power distribution system electric vehicles load demand.

The growing concerns regarding the depletion of fossil fuels, CO emissions, and the effects of climate change prompt the usage of plug-in electric vehicles (PHEVs) all over the world in a big way. The increased electrical demand brought on by the charging of electric vehicles puts a burden on the distribution network parameters like energy loss, voltage profile and thermal limits. Recently, renewable energy-based distribution generation (RDGs) units are firmly integrated with the transmission and distribution system networks to lower the carbon footprint generated due to conventional thermal power plants.

The landscape of intrinsically disordered proteins in Leishmania parasite: Implications for drug discovery.

Proteins that lack three-dimensional structures are known as Intrinsically disordered proteins (IDPs). In this study, we aimed to identify intrinsically disordered proteins in the Leishmania donovani proteome using various predictors that can identify IDPs based on amino acid residues and charge hydropathy. Top identified IDPs are analyzed using STRING, PSP-Hunter, Deep Loc-2.

Comprehensive Comparative Study of the Durability Wear Assessment of a Diesel Engine Fuelled with Seed Oil and Diesel Fuel and Its Troubleshooting and Scheduled Maintenance.

Existing ecofriendly apprehensions about climate change have directed scientists to discover plant-based vegetable oils for use as fuels, such as straight vegetable oils and their biodiesels, because of their renewability, nontoxic nature, biodegradability, and environmental friendliness. This experimental study intended to reveal the tribological aspects of 90 °C preheated straight vegetable oil (PHSVO90) used in a 7.35 kW, 1000 rpm constant speed indirect injection (IDI) diesel engine and likened to conventional diesel operation by conducting an elongated term durability examination for 512 h as per IS:10000 standards.

Copper-assisted anticancer activity of hydroxycinnamic acid terpyridine conjugates on triple-negative breast cancer.

The development of active therapeutic agents to treat highly metastatic cancer while minimizing damage to healthy cells is of utmost importance. Due to potential antioxidant properties, hydroxycinnamic acid derivatives (caffeic acid and -coumaric acids) were found to inhibit highly metastatic breast cancer cell growth both and without much effect on normal cells. Especially due to the structure-activity relationships, ester and amide derivatives of hydroxycinnamic acids are reported to gain much higher radical scavenging ability than their naked hydroxycinnamic acid analogs like caffeic acid and -coumaric acid.

Silicon dioxide incorporated cellulose acetate-mixed matrix membranes for Safranin-O removal from aqueous solutions.

Nanoparticle incorporated-mixed matrix membranes are renowned for their multifaceted advantages, including improved hydrophilicity, elevated solute rejection, enhanced mechanical robustness, and augmented chemical and thermal stability. The inherent hydrophilicity of silicon dioxide (SiO) nanoparticles, due to silanol groups (Si-OH), along with their high porosity and surface area, renders them an ideal reinforcing filler within polymer matrices, significantly strengthening structural integrity of membranes. In this work, SiO nanoparticles were incorporated in a cellulose acetate (CA) matrix to prepare CA/SiO adsorptive membranes using phase inversion method.

Origin of a Kinetically Selective Route for Thermoreversible Valence Tautomerism-Based Photoswitching in -Heterocycles Containing Conjugated Dienes.

The thermal electrocyclic ring opening of fused -cyclobutene to ,-diene is prohibited according to the Woodward-Hoffmann (WH) rules; nonetheless, experiments provide firm evidence for their formation. However, the mechanism, electronic structure, and behavior during the reaction are ambiguous. Herein, we attempt to gain insights into the mechanism of thermal ring opening in four -heterocycles containing a conjugated diene as the core skeleton.

Ni- and Co-Based MOF-Derived NiCoO Materials: As an Efficient Anode for Direct Methanol Fuel Cell Application.

Finding inexpensive and efficient anode materials is crucial for the oxidation of methanol in the direct methanol fuel cell (DMFC), which is the key electrode reaction. Herein, we report metal-organic framework (MOF)-derived CoO, NiO, and NiCoO (where = 1.5, 1, and 0.

Rongalite induced metal-free C(sp)-H functionalization of indoles: direct access to 3-(sulfonylmethyl) indoles.

A rongalite-induced C(sp)-H functionalization reaction has been developed for the synthesis of 3-(phenylsulfonylmethyl) indole derivatives from indole and arylsulfonyl hydrazides. This regioselective C-H functionalization provides a wide range of C-3 sulfonylmethyl indoles with upto 90% yields. Here, rongalite functions as a C1 unit source and a single electron donor.

Validation of Low Cost Patient Specific Implant Design Using Finite Element Analysis (FEA) for Reconstruction of Segmental Mandibular Defects: A Case Report and Literature Review.

Introduction: Mandibular continuity defects can cause functional and cosmetic deformities affecting a patient's quality of life. Reconstruction of such defects can be intricate even for the most seasoned maxillofacial surgeons. Reconstruction plates were the standard of care in the past, followed by a secondary reconstruction using autogenous grafts.

Energy curve based enhanced smell agent optimizer for optimal multilevel threshold selection of thermographic breast image segmentation.

Multilevel thresholding image segmentation will subdivide an image into several meaningful regions or objects, which makes the image more informative and easier to analyze. Optimal multilevel thresholding approaches are extensively used for segmentation because they are easy to implement and offer low computational cost. Multilevel thresholding image segmentation is frequently performed using popular methods such as Otsu's between-class variance and Kapur's entropy.

Bioelectrochemical biosensors for water quality assessment and wastewater monitoring.

Bioelectrochemical biosensors offer a promising approach for real-time monitoring of industrial bioprocesses. Many bioelectrochemical biosensors do not require additional labelling reagents for target molecules. This simplifies the monitoring process, reduces costs, and minimizes potential contamination risks.

Unveiling the Obscure Potential of O-Carborane Based IFLPs for CO Sequestration.

Sequestering carbon dioxide (CO) from the atmosphere is necessary to achieve a sustainable environment. However, the thermodynamic stability of the CO molecule poses a significant challenge to its capture, necessitating catalysts that can overcome this stability. The emergence of frustrated Lewis pairs (FLPs) has opened a new dimension in the development of organocatalysts for CO capture and utilization.

I-catalyzed tandem sp C-H oxidation and annulation of aryl methyl ketones with amidoximes for the synthesis of 5-aroyl-1,2,4-oxadiazoles.

A metal-free, iodine-catalyzed protocol has been developed for constructing biologically significant 5-aroyl 1,2,4-oxadiazole scaffolds using aryl methyl ketones and amidoximes. The strategy produces structurally diverse 5-aroyl 1,2,4-oxadiazoles in good to excellent yields, with a broad substrate scope that includes drug derived substrates. The reaction proceeds through iodine/DMSO-mediated oxidation of aryl methyl ketones, followed by imine formation and subsequent cyclization to yield the desired products.

Numerical model of debris flow susceptibility using slope stability failure machine learning prediction with metaheuristic techniques trained with different algorithms.

In this work, intelligent numerical models for the prediction of debris flow susceptibility using slope stability failure factor of safety (FOS) machine learning predictions have been developed. These machine learning techniques were trained using novel metaheuristic methods. The application of these training mechanisms was necessitated by the need to enhance the robustness and performance of the three main machine learning methods.

Do two-wheeler riders propel towards autonomous driving? A path-based probabilistic study in Indian context.

Regardless of the rational benefits of autonomous vehicle adoption towards mitigating mobility goals in urban and sub-urban areas of middle-income countries, adoption of such technology remains thought-provoking. Two wheeled vehicles are often utilized extensively all over the world for short distance trips in sub-urban areas. The present study investigates perceived risks of using four wheeled autonomous vehicles by captive two-wheeler riders for long and short distance trips in densely populated Indian cities.

Iodine-promoted sequential C(sp)-H oxidation and cyclization of aryl methyl ketones with 2-(2-aminophenyl)quinazolin-4(3)-ones.

An I-promoted, metal-free protocol has been developed for the one-pot synthesis of 6-aroyl-5,6-dihydro-8-quinazolino[4,3-]quinazolin-8-ones from readily accessible substrates. This reaction involves the sp C-H oxidation of aryl methyl ketones to phenylglyoxal, followed by imine formation and intramolecular nucleophilic addition, resulting in the formation of two new C-N bonds. Furthermore, the method is applicable to a wide range of aryl methyl ketones, including heterocycles and drug-derived substrates, yielding the desired products with yields ranging from 62% to 93%.

DOTAP Modified Formulations of Aminoacid Based Cationic Liposomes for Improved Gene Delivery and Cell Viability.

The liposomal systems proved remarkably useful for the delivery of genetic materials but enhancing their efficacy remains a significant challenge. While structural alterations could result in the discovery of more effective transfecting lipids, improving the efficacy of widely used lipid carriers is also crucial in order to compete with viral vectors for gene delivery. Herein, we developed formulations of commercially available lipid, 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) with synthetic amino acid based cationic lipids.

Orbital and free energy landscape expedition towards the unexplored catalytic realm of aromatically modified FLPs for CO sequestration.

The emergence of frustrated Lewis pairs (FLPs) has created a whole new dimension in the development of metal free catalysts for CO sequestration. Efforts have been made to enhance the catalytic activity of the FLPs. The aromatic modulation of the catalytic sites has been successfully demonstrated to enhance the activity towards CO.

Enhanced reducing sugar production by blending hydrolytic enzymes from Aspergillus fumigatus to improve sugarcane bagasse hydrolysis.

Biomass pretreatment for the production of second-generation (2G) ethanol and biochemical products is a challenging process. The present study investigated the synergistic efficiency of purified carboxymethyl cellulase (CMCase), β-glucosidase, and xylanase from Aspergillus fumigatus JCM 10253 in the hydrolysis of alkaline-pretreated sugarcane bagasse (SCB). The saccharification of pretreated SCB was optimised using a combination of CMCase and β-glucosidase (C + β; 1:1) and addition of xylanase (C + β + xyl; 1:1:1).