Effectiveness of structured teaching program on parents' knowledge about child physical abuse.

Background: The issue of child physical abuse (CPA) is complex and challenging to study. According to World Health Organization fact sheets for 2020, about 3 in 4 children between 2 and 4 years of age regularly face physical maltreatment by parents or caregivers. It may cause a lifelong impact on physical and mental health.

Feasibility and preliminary efficacy of training health workers in detecting Priority Mental Health Conditions among adolescents in rural South India.

Introduction: Half of all mental disorders start during adolescence, before 14 years. In India, the current prevalence of mental disorders in 13-17 years age group was 7.3%.

Determining chromosomal arms 1p/19q co-deletion status in low graded glioma by cross correlation-periodogram pattern analysis.

Prediction of mutational status of different graded glioma is extremely crucial for its diagnosis and treatment planning. Currently FISH and the surgical biopsy techniques are the 'gold standard' in the field of diagnostics; the analyses of which helps to decide appropriate treatment regime. In this study we proposed a novel approach to analyze structural MRI image signature pattern for predicting 1p/19q co-deletion status non-invasively.

Unveiling the Effects of Rare-Earth Substitutions on the Structure, Mechanical, Optical, and Imaging Features of ZrO for Biomedical Applications.

The impact of selective rare-earth (RE) additions in ZrO-based ceramics on the resultant crystal structure, mechanical, morphological, optical, magnetic, and imaging contrast features for potential applications in biomedicine is explored. Six different RE, namely, Yb, Dy, Tb, Gd, Eu, and Nd alongside their variations in the dopant concentrations were selected to accomplish a wide range of combinations. The experimental observations affirmed the roles of size and dopant concentration in determining the crystalline phase behavior of ZrO.

Rehabilitation in Schizophrenia: A Brain-behavior and Psychosocial Perspective.

Cognitive deficits in patients with schizophrenia have been documented consistently. They are known to contribute to functional impairment in patients. Cognitive remediation has been found to be beneficial in symptoms reduction and functional recovery.

Clinical and radiological assessment of cerebral hemodynamics after cranioplasty for decompressive craniectomy - A Clinical study.

Objectives: To find the correlation between radiologically proven improvement in cerebral hemodynamics with clinical improvement in patients undergoing cranioplasty.

Material And Methods: The study is a prospective observational study of 10 cases, in M S Ramaiah Institute of Neurosciences, involving patients treated by a decompressive craniectomy for intractable intra cranial hypertension either due to trauma or stroke and afterwards underwent cranioplasty.

Results: Of the 10 patients, 70% patients showing significant improvement in motor functions on Barthel index scale, 60% patients showed improvement in speech, mean duration from date of decompressive craniectomy to cranioplasty being 122.

F-18 fluorodeoxyglucose positron emission tomography study of impaired emotion processing in first episode schizophrenia.

Background: Schizophrenia cases have been consistently shown to have behavioural and neurofunctional abnormalities but studies during early course are scarce. The present work assesses the performance of acute first episode schizophrenia cases on correlation of a facial emotion perception task with brain function using fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET).

Methods: Twenty First episode schizophrenia cases and 20 matched healthy controls living in the community were enrolled.

Understanding the pathophysiology of reflex epilepsy using simultaneous EEG-fMRI.

Measuring neuro-haemodynamic correlates in the brain of epilepsy patients using EEG-fMRI has opened new avenues in clinical neuroscience, as these are two complementary methods for understanding brain function. In this study, we investigated three patients with drug-resistant reflex epilepsy using EEG-fMRI. Different types of reflex epilepsy such as eating, startle myoclonus, and hot water epilepsy were included in the study.

Unraveling Brain Functional Connectivity of encoding and retrieval in the context of education.

Human memory is an enigmatic component of cognition which many researchers have attempted to comprehend. Accumulating studies on functional connectivity see brain as a complex dynamic unit with positively and negatively correlated networks in perfect coherence during a task. We aimed to examine coherence of network connectivity during visual memory encoding and retrieval in the context of education.

Projection of cancer incidence in five cities and cancer mortality in India.

Background: Cancer is second largest non-communicable disease and it has a sizable contribution in the total number of deaths. It is important for the public health professionals to understand the dynamics of cancer incidence for future strategies. Therefore, this paper is attempted with the objective of projecting number of cancer incidence for five cities namely, Bangalore, Chennai, Delhi, Bhopal and Mumbai and to estimate the cancer mortality rate for all India for the year 2008.

Non-traumatic acute rhabdomyolysis.

A boy developed sudden severe generalized muscle stiffness, bulbar weakness and passed dark coloured urine. Laboratory tests revealed marked elevation of creatinine kinase(CK) levels and myoglobinuria. Histopathology of quadriceps muscle showed features of acute rhabdomyolysis.

Structural alterations induced by photodynamic action of hematoporphyrin derivative (HpD) in plasma membrane of glioblastoma (U-87MG) cells: time dependent fluorescence spectroscopic study.

Photodynamic action of hematoporphyrin derivative (HpD) on the plasma membrane of human glioblastoma U-87MG cells was investigated using lipid and protein specific fluorescent probes trimethylammonium-1,6-diphenyl 1,3,5-hexatriene (TMA-DPH) and N-(1-pyrene)-maleimide (PM) respectively. Steady state anisotropy, decay time and time dependent anisotropy of these probes in U-87MG cells were measured. Light irradiation caused an increase in the steady state anisotropy of TMA-DPH in cells treated with HpD; however, no change in decay time was observed.

Hematoporphyrin derivative binding and photosensitization in human glioblastoma cells: comparison of exponential and plateau phase cells.

Plateau phase glioblastoma (U 87MG) cells were found more photosensitive than the exponentially growing cells. In both phases of growth, the photosensitivity showed further enhancement on incubating the cells with HpD for longer duration. Plateau phase cells accumulated more HpD than exponential phase cells for shorter duration of incubation with HpD, however, for longer duration of incubation, the amount of drug uptake was almost the same in both phases of growth.

Phosphatase activity against neurofilament proteins from bovine spinal cord: effect of aluminium and neuropsychoactive drugs.

Protein phosphatase activity associated with neurofilament (NF) rich (Triton X-100 insoluble) fraction was extracted and partially characterised by using known inhibitors of protein phosphatases such as vanadate and fluoride. Protein phosphatase activity was demonstrated with reference to the dephosphorylation of endogenous substrate, NF protein and exogenous protein substrates, casein and phosvitin. Phosphoamino acids and beta-glycerophosphate were found to be poor substrates.