21,294 results match your criteria: "National Institute of Mental[Affiliation]"

Neural Rewiring of Resilience: The Effects of Combat Deployment on Functional Network Architecture.

Biol Psychiatry Cogn Neurosci Neuroimaging

January 2025

School of Psychological Sciences, Sagol School of Neuroscience, Tel-Aviv University.

Background: Although combat-deployed soldiers are at a high risk for developing trauma-related psychopathology, most will remain resilient for the duration and aftermath of their deployment tour. The neural basis of this type of resilience is largely unknown, and few longitudinal studies exist on neural adaptation to combat in resilient individuals for whom a pre-exposure measurement was collected. Here, we delineate changes in the architecture of functional brain networks from pre- to post-combat in psychopathology-free, resilient participants.

View Article and Find Full Text PDF

The shift toward a histo-molecular approach in World Health Organization classification of central nervous system tumors (WHO CNS5) emphasizes the critical role of molecular testing, such as next-generation sequencing (NGS) and DNA methylation profiling, for accurate diagnosis. However, implementing these advanced techniques is particularly challenging in resource-constrained countries. To address this, the Asian Oceanian Society of Neuropathology committee for Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Restrained Regions (AOSNP-ADAPTR) was initiated to help pathologists in resource-limited regions to implement WHO CNS5 diagnoses using simpler diagnostic tools, mainly immunohistochemistry.

View Article and Find Full Text PDF

Auditory/visual hallucinations and perceptual anomalies are one of the core symptoms experienced by patients with schizophrenia. Studies have implicated lateral occipital cortex (LOC) as one of the areas to be aberrantly functioning in schizophrenia, possibly associated with the auditory/visual symptoms of schizophrenia. Here we report of a case of a 29-year-old female diagnosed with treatment resistant schizophrenia on clozapine with persistent auditory verbal hallucinations (AVH) and visual anomalies.

View Article and Find Full Text PDF

Background: Prevention of depression, stress, and anxiety is a serious concern of the World Health Organization and has been a research topic over the last decades. There is a close association found between children's mental health problems and parental stress, valid for biological and foster families. Evidence suggests that parents with children with disabilities are more stressed, depressed, or anxious than parents who do not have such children.

View Article and Find Full Text PDF

Background: Agile methodology (AM) is an innovative, active, project-based learning method. The scrum is a popular agile framework widely used in project management and education. This study evaluates the opinions on agile adaptation in nursing curricula among nursing students to identify how AM can be applied in higher education to facilitate learning.

View Article and Find Full Text PDF

Traumatic aneurysms represent less than 1 percent of intracranial aneurysms and middle meningeal artery pseudoaneurysms are even rare. Traumatic aneurysms are usually pseudoaneurysms formed by the rupture of all the layers of the vessel wall. They are associated with high mortality as they can present as epidural, subdural, and rarely intraparenchymal hematoma.

View Article and Find Full Text PDF

In modern society, many workers struggle with sleep deprivation due to their work schedules and excessive workloads. Accurate self-awareness and self-monitoring abilities are crucial for workers to adopt risk-coping strategies and protective behaviors when fatigued. The current study examined the relationship between chronotypes and self-monitoring performance during 24 h of sleep deprivation.

View Article and Find Full Text PDF

Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with Extradenticle and Homothorax.

PLoS Genet

January 2025

Centro de Biología Molecular Severo Ochoa (CBM), CSIC-UAM, Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

Hox proteins, a sub-group of the homeodomain (HD) transcription factor family, provide positional information for axial patterning in development and evolution. Hox protein functional specificity is reached, at least in part, through interactions with Pbc (Extradenticle (Exd) in Drosophila) and Meis/Prep (Homothorax (Hth) in Drosophila) proteins. Most of our current knowledge of Hox protein specificity stems from the study of anterior and central Hox proteins, identifying the molecular and structural bases for Hox/Pbc/Meis-Prep cooperative action.

View Article and Find Full Text PDF

Turning Your Presentations/Posters to Publications.

Indian J Radiol Imaging

January 2025

Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

A scientific manuscript or paper is invariably the ultimate goal of most scientific endeavors and in a majority of cases, the final manuscript often begins as an abstract submitted to a conference to be presented as either a poster or an oral presentation. It is practically possible for authors to use a conference presentation as a basic template to expand and write a complete manuscript. However, it is imperative for authors to acknowledge the limitations of these abstracts and make attempts to improve the quality of work before embarking on writing a full-length manuscript.

View Article and Find Full Text PDF

Background: Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing central nervous system disease most commonly associated with aquaporin-4 antibodies (AQP4-Ab) and Myelin oligodendrocyte glycoprotein (MOG) antibodies. These demyelinating disorders influence cortical excitability, which has been studied using advanced imaging techniques and transcranial magnetic stimulation (TMS) in our study.

Methods: This is a prospective study of 30 subjects.

View Article and Find Full Text PDF

Machine Learning-enhanced X-ray-based Radiomics in the Identification of Post-COVID Patients.

Arch Bronconeumol

December 2024

National Koranyi Institute of Pulmonology, Budapest, Hungary; Department of Thoracic Surgery, Semmelweis University and National Institute of Oncology, Budapest, Hungary; Department of Thoracic Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

View Article and Find Full Text PDF

Fear extinction retention in children, adolescents, and adults.

Dev Cogn Neurosci

January 2025

Department of Medical Sciences, Experimental Cognitive and Affective Neuroscience Lab, Uppsala University, Uppsala, Sweden. Electronic address:

Past results suggest that fear extinction and the return of extinguished fear are compromised in adolescents. However, findings have been inconclusive as there is a lack of fear extinction and extinction retention studies including children, adolescents and adults. In the present study, 36 children (6-9 years), 40 adolescents (13-17 years) and 44 adults (30-40 years), underwent a two-day fear conditioning task.

View Article and Find Full Text PDF

The cerebellum is involved in non-motor processing, supported by topographically distinct cerebellar activations and closed-loop circuits between the cerebellum and the cortex. Disruptions to cerebellar function may negatively impact prefrontal function and processing. Cerebellar resources may be important for offloading cortical processing, providing crucial scaffolding for normative performance and function.

View Article and Find Full Text PDF

Day-to-day variability in sleep and activity predict the onset of a hypomanic episode in patients with bipolar disorder.

J Affect Disord

January 2025

Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Campbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

Detecting transitions in bipolar disorder (BD) is essential for implementing early interventions. Our aim was to identify the earliest indicator(s) of the onset of a hypomanic episode in BD. We hypothesized that objective changes in sleep would be the earliest indicator of a new hypomanic or manic episode.

View Article and Find Full Text PDF

The origin of color categories.

Proc Natl Acad Sci U S A

January 2025

Section on Perception, Cognition, Action, Laboratory of Sensorimotor Research, National Eye Institute, NIH, Bethesda, MD 20892.

To what extent does concept formation require language? Here, we exploit color to address this question and ask whether macaque monkeys have color concepts evident as categories. Macaques have similar cone photoreceptors and central visual circuits to humans, yet they lack language. Whether Old World monkeys such as macaques have consensus color categories is unresolved, but if they do, then language cannot be required.

View Article and Find Full Text PDF

Aim: The Internet Gaming Disorder Scale is a 9-item screening instrument developed based on the diagnostic criteria for Internet Gaming Disorder (IGD) in the DSM-5. This study aimed to examine the reliability and validity of the Internet Gaming Disorder Scale for children (IGDS-C) in Japanese clinical and nonclinical populations.

Methods: The study included clinical outpatients aged 9-29 with problematic game use and nonclinical adolescents aged 12-18 who played online games at least once a week.

View Article and Find Full Text PDF

Use of psychedelic treatments in psychiatric clinical practice: an EPA policy paper.

Eur Psychiatry

January 2025

Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium.

Background: Recent years show an exponential increased interest ("renaissance") in the use of psychedelics for the treatment of mental disorders and broader. Some of these treatments, such as psilocybin for depression, are in the process of formal regulation by regulatory bodies in the US (FDA) and Europe (EMA), and as such on the brink of real-world implementation. In the slipstream of these developments increasing commercial initiatives are taking shape.

View Article and Find Full Text PDF

Background The synthetic opioid tramadol is widely used as a pain reliever. Unlike other opioids, it is used freely worldwide, unaffected by international controls resulting in abuse and accidental intoxication. Analytical methods are necessary to prove tramadol abuse because 30% of the drug is excreted unchanged.

View Article and Find Full Text PDF

Radiosynthesis of [18F]-flumazenil Using an Isotopic Approach.

Indian J Nucl Med

November 2024

Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background: Fluorine-18 (F) flumazenil (FMZ) has been synthesized using various precursors, and its role has been explored in imaging Gamma-aminobutyric acid-A receptors.

Aim And Objective: The main objective was to synthesize (F) FMZ using isotopic substitution.

Materials And Methods: Around 18 ± 2 GBq was added to the module, dried, and radiolabeling was standardized with 3.

View Article and Find Full Text PDF

Introduction: With increased urbanization the prevalence of important public health problems like road traffic accidents (RTA) and depression are surging. This study was aimed to determine the association between RTA and depression among Indian population aged ≥45 years.

Methods: Using Longitudinal Aging Study in India (LASI) dataset (April 2017-December 2018), we have conducted this study among older adults (45-59 years) and elderly (≥60 years) Indians.

View Article and Find Full Text PDF