342 results match your criteria: "National Institute of Laser Enhanced Sciences[Affiliation]"

Objective: We sought to compare the safety and efficacy of combining fractional 2940-nm Erbium:YAG (Er:YAG) laser with autologous platelet-rich plasma (PRP) versus its combination with low-level laser therapy (LLLT) for enhancing the outcome of postsurgical and post-traumatic scars.

Methods: Fourty-five individuals with post-surgical or post-traumatic scars were randomly divided into three groups: Group A received four fractional Er:YAG laser sessions spaced four weeks apart along with eight sessions of intradermal PRP injections spaced two weeks apart; Group B received four fractional Er:YAG laser sessions spaced four weeks apart along with two sessions of light emitting diode (LED) weekly; and Group C received four fractional Er:YAG laser sessions spaced four weeks apart. Treatment efficacy was evaluated using clinical photographs, Vancouver Scar Scale (VSS), patient satisfaction and histopathology.

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Exploring the Role of Exosomal lncRNA in Cancer Immunopathogenesis: Unraveling the Immune Response and EMT Pathways.

Exp Cell Res

December 2024

Medical Laboratory Technique College, The Islamic University, Najaf, Iraq; Medical Laboratory Technique College, The Islamic University of Al Diwaniyah, Al Diwaniyah, Iraq; Medical Laboratory Technique College, The Islamic University of Babylon, Babylon, Iraq. Electronic address:

Exosomes are membrane-bound vesicles secreted by diverse cell types, serving as crucial mediators in intercellular communication and significantly influencing cancer development. Exosomes facilitate complex signaling processes in the tumor microenvironment for immunomodulation, metastasis, angiogenesis, and treatment resistance. Notably, long non-coding RNAs (lncRNAs), a class of non-coding RNAs, engage with mRNA, DNA, proteins, and miRNAs to modulate gene expression through multiple mechanisms, including transcriptional, post-transcriptional, translational, and epigenetic pathways.

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Corneal alkali burns persist as a significant challenge in our field, often leading to a prolonged treatment course with various sight-threatening problems. This work, of utmost importance, aimed to apply the photo-tissue bonding technique (PTB) to weld the amniotic membrane (AM) to the corneal surface versus an amniotic membrane graft (AMG) and explore its safety in saving corneal protein against alkali burn.Methods Twenty-seven rabbits with an induced corneal ulcer using 1 mol/L NaOH solution.

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Targeting breast tumor extracellular matrix and stroma utilizing nanoparticles.

Clin Transl Oncol

December 2024

Department of Refrigeration and air Conditioning Techniques, College of Technical Engineering, The Islamic University, Najaf, Iraq.

Breast cancer is a complicated malignancy and is known as the most common cancer in women. Considerable experiments have been devoted to explore the basic impacts of the tumor stroma, particularly the extracellular matrix (ECM) and stromal components, on tumor growth and resistance to treatment. ECM is made up of an intricate system of proteins, glycosaminoglycans, and proteoglycans, and maintains structural support and controls key signaling pathways involved in breast tumors.

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Melatonin enhances metal oxide nanoparticles tolerance in rice seedlings through dual regulation of antioxidant defense and photosynthetic efficiency.

Physiol Plant

December 2024

Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Zhongshan Biological Breeding Laboratory/Key Laboratory of Plant Functional Genomics of the Ministry of Education, Agriculture College of Yangzhou University, Yangzhou, China.

The growing utilization of metal oxide nanoparticles (MONPs) presents novel and potential hazards to plants. However, the impacts of MONPs on plants and the mechanisms underlying their tolerance to MONPs remain unclear. In this study, we demonstrated that both CuO and ZnO nanoparticles hindered plant growth and triggered oxidative damage in rice seedlings.

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Background: Psoriasis is a common chronic systemic disease affecting the skin, nails, and joints. Nails are commonly associated with a greater severity of the disease. Radiofrequency (RF) is a nonionizing radiation that provides energy originating from electric current to generate heat inside the dermis with anti-inflammatory effects.

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Article Synopsis
  • The study explores how infrared diode laser treatment affects the growth and development of periodontal ligament stem cells (hPDLSCs), which are crucial for dental tissue repair.
  • Infrared laser application at a specific power and duration significantly improved the viability and differentiation of hPDLSCs, showcasing increased expression of important stem cell and osteogenic markers.
  • These results highlight potential clinical uses of infrared lasers combined with stem cells to enhance periodontal tissue regeneration and improve dental healing processes.
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The telecommunication wavelengths are crucial for developing a photonic integrated circuit (PIC). The absorption fingerprints of many gases lie within these spectral ranges, offering the potential to create a miniaturized gas sensor for PIC. This work presents novel double Fano resonances within the telecommunication band, based on silicon metasurfaces for selective gas sensing applications.

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Chemotherapy is the most common cancer treatment, and metallic anticancer compounds have generated increasing amounts of interest since the discovery of cisplatin. More recently, scientists have focused on ruthenium-based compounds as alternatives for platinum compounds, which seem like ideal therapeutic anticancer alternatives to platinum derivatives. The present study aims to assess whether one or more of three Ruthenium-based nanocomposites, namely Ru+Lysine+CTAB (RCTL), Ru+CTAB (RCT), and Ru+Lysine (RL) exhibit pronounced anti-proliferative properties against different cancer cells.

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Article Synopsis
  • Cellulite (CLT) is a common cosmetic issue for women, characterized by dimpled skin, and is usually treated with invasive methods like liposuction, but safer topical treatments are preferred.
  • This study developed a solid lipid nanoparticle formulation containing caffeine (CA) to enhance its absorption and effectiveness against cellulite, achieving high entrapment efficiency and optimal particle characteristics.
  • The final product, CA-SLN-Ngel, demonstrated significant reductions in subcutaneous fat tissue thickness in histological studies, suggesting it could be an effective non-invasive treatment for cellulite.
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Aluminum phthalocyanine tetrasulfonate conjugated to surface-modified Iron oxide nanoparticles as a magnetic targeting platform for photodynamic therapy of Ehrlich tumor-bearing mice.

Photodiagnosis Photodyn Ther

December 2024

Pharmaceutical Nanotechnology Unit, Department of Medical Applications of Laser, National Institute of Laser Enhanced Sciences, Cairo University, Egypt. Electronic address:

Background: Photodynamic therapy (PDT) is a targeted treatment option for cancers that are non-responding to ordinary anticancer therapies. It involves activating a photosensitizer with a light source of a specific wavelength to destroy targeted cells and their surrounding vasculature. Aluminum phthalocyanine tetra sulfonate (AlPcS) has gained attention as a second-generation photosensitizer for its strong absorption in the red-light region.

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Atrazine is a widely used toxic herbicide that poses a threat to both the environment and human health. This study investigates the removal of Atrazine from water through armchair-hexagonal hexagonal graphene quantum dots (AHEX) simulations. The investigations are performed using density functional theory at the exchange-correlation hybrid functional B3LYP/3-21G level of theory.

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Smart photochromic and fluorescent textile refers to garments that alter their colorimetric properties in response to external light stimulus. Cotton fibers have been reported as a main resource for many textile and non-textile industries, such as automobiles, medical devices, and furniture applications. Cotton is a natural fiber that is distinguished with breathability, softness, cheapness, and highly absorbent.

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In recent research, there has been a significant focus on establishing robust quantum cryptography using the continuous-variable quantum key distribution (CV-QKD) protocol based on Gaussian modulation of coherent states (GMCS). Unlike more stable fiber channels, one challenge faced in free-space quantum channels is the complex transmittance characterized by varying atmospheric turbulence. This complexity poses difficulties in achieving high transmission rates and long-distance communication.

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Using plant extracts as photosensitizers in photodynamic therapy (PDT) represents a significant green approach toward sustainability. This study investigates beetroot juice (BRJ), betanin, and their liposomal formulations (Lip-BRJ, Lip-Bet) as photosensitizers in cancer PDT. BRJ was prepared, and its betanin content was quantified via HPLC.

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Laser corneal reshaping is a safe and effective technique utilized to treat common vision disorders. An advanced laser delivery system equipped with a pulsed UV laser with specific parameters is used to ablate parts of the cornea surface to correct the existing refractive error. The argon fluoride (ArF) excimer pulsed gas laser at 193 nm is the most employed type in the commercial devices for such treatments.

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The beekeeping industry plays a crucial role in local economies, contributing significantly to their growth. However, bee colonies often face the threat of American foulbrood (AFB), a dangerous disease caused by the Gram-positive bacterium Paenibacillus larvae (P. l.

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Molybdenum trioxide (MoO) is an attractive semiconductor. Thus, bandgap engineering toward photoelectronic applications is appealing yet not well studied. Here, we report the incorporation of sulfur atoms into MoO, using sulfur powder as a source of sulfur, via a self-developed hydrothermal synthesis approach.

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Could Photobiomodulation help lactating women and their newborns?

Lasers Med Sci

July 2024

National Institute of Laser Enhanced Sciences (N.I.L.E.S), Cairo University, House 2 Street 6 Zahraa Helwan, Giza, Niles, Cairo, Egypt.

During the first several weeks following lactation, nipple pain frequently prevents mothers from continuing breastfeeding. To evaluate the efficacy of using Photobiomodulation (PBM) versus anti-inflammatory topical cream, on inflamed nipple, and the effect on milk production. This study was carried-out on 50 breastfeeding women with nipple pain and fissure.

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ER:YAG laser and experimental resin-based dental adhesive loaded with functionalized carbonated apatite filler were used in this study to evaluate the dentin interaction in terms of penetration and occlusion of the dentinal tubules aiding in the control of dentin hypersensitivity (DH). Spheroidal Carbonated apatite nanoparticles (N-CAP), with an average size of 20±5 nm diameter, were synthesized, characterized, and incorporated in a universal adhesive "All Bond Universal, Bisco, USA", in (2% weight) concentration. Er:YAG laser "Lightwalker, FOTONA, EU" was adjusted to an energy output of 40mJ/ pulse and pulse repetition of 10 Hz for 10 seconds.

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Adhesive dentistry has made it feasible to design restorations with high aesthetic qualities and little invasiveness. However, the freshly cut dentin after the tooth preparation needs to be sealed to prevent its contaminations, bacterial leakage, and hypersensitivity. Consequently, the immediate dentin sealing (IDS) method has been advised.

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Methylene blue dye, being toxic, carcinogenic and non-biodegradable, poses a serious threat for human health and environmental safety. The effective and time-saving removal of such industrial dye necessitates the use of innovative technologies such as silver nanoparticle-based catalysis. Utilizing a pulsed Nd:YAG laser operating at the second harmonic generation of 532 nm with 2.

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Long-pulsed nd: YAG laser treatment of nail psoriasis: clinical and ultrasonographic assessment.

Arch Dermatol Res

June 2024

Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.

Article Synopsis
  • - Nail psoriasis is a tough-to-treat, chronic inflammatory condition that can severely impact quality of life and is linked to greater psoriasis severity, as well as anxiety.
  • - A study examined the effectiveness of the long-pulsed 1064 nm Nd: YAG laser in treating fingernail psoriasis compared to untreated control nails by assessing various factors including the NAPSI score and ultrasonographic measures.
  • - Results showed significant improvement in the laser-treated group for several clinical and ultrasonographic metrics, while the control group showed only a slight, non-significant improvement, indicating that the Nd: YAG laser may be beneficial for managing nail psoriasis.
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Purpose: Conventional approaches for enhancing wound healing may not always yield satisfactory results. Instead, we test the effectiveness of a newly developed photodynamic therapy (PDT) that uses methylene blue (MB) loaded with polyethylene glycol (PEG) (MB-PEG) hydrogel to accelerate wound healing process in mice.

Methods: A dorsal skin incision with 6 mm punch which topically subjected to MB-PEG hydrogel and a low-level laser light of red light to assess the regeneration process of wounded skin.

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