Evaluation of gestational weight gain in women with twin pregnancies and its relationship to neonatal birth weight. A pilot study.

Background: To date, there have been no studies in Poland on weight gain in women with twin pregnancies in relation to recommendations.

Objective: The aim of this study was to analyze the gestational weight gain of women with twin pregnancies depending on their body weight before pregnancy, and to assess the relationship between the observed weight gain and the neonatal birth weight.

Material And Methods: The study was conducted among 50 women in twin pregnancies and their 100 newborns delivered after 36 weeks of gestation.

The HPV prevention and control program in Poland: progress and the way forward.

This review assesses Poland's activities in preventing and managing human papillomavirus (HPV)-related diseases, summarizing information from the 2023 HPV Prevention and Control Board meeting. Progress in primary, secondary, and tertiary prevention identifies opportunities to strengthen control of cervical cancer. Poland's national HPV vaccination program, launched in June 2023, initially achieved suboptimal coverage.

Latent Tuberculosis Infections in Different Intensity of Exposure within Moroccan Population: Influence of Age and Bacille Calmette-Guérin Vaccination.

Background: In Morocco, latent tuberculosis infection (LTBI) is a public health concern affected by the country's location as transit area between sub-Saharan Africa with high TB burden to Europe. This study aimed to assess the influence of exposure intensity to Mycobacterium tuberculosis (Mtb), age, and Bacille Calmette-Guérin (BCG) vaccination on LTBI prevalence in Morocco.

Methods: A cross-sectional study of 131 participants, including 98 non-exposed healthy volunteers (NEHV) and 33 healthcare workers exposed to active TB (exposed healthcare workers [EHCW]), was conducted.

Low-inflammatory lipid nanoparticle-based mRNA vaccine elicits protective immunity against H5N1 high-pathogenicity avian influenza virus with reduced adverse reactions.

Messenger RNA vaccines based on lipid nanoparticles (mRNA-LNPs) are promising vaccine modalities. However, mRNA-LNP vaccines frequently cause adverse reactions such as swelling and fever in humans, partly due to the inflammatory nature of LNP. Modification of the ionizable lipids used in LNP is one approach to avoid these adverse reactions.

[The changing epidemiology of tick-borne encephalitis: epidemic surveillance and disease prevention challenges].

The increasing number of cases of tick-borne encephalitis (TBE) reported in recent years in Europe and, more recently, in Poland is a consequence of factors related to climate and environmental change leading to increasing tick populations and human behavior favoring exposure. In Poland, there is considerable regional variation in the incidence of TBE, resulting, among other factors, from underreporting of all cases and limited access to laboratory diagnostics. The consequence is low public awareness of the disease and insufficient use of vaccination as optimal prevention.

Mosquito populations originating from nonendemic areas have the potential to transmit recently emerging Japanese encephalitis virus genotype IV.

Japanese encephalitis virus (JEV) genotype IV (GIV) is one of the least common and most neglected genotypes worldwide, having been identified only on a few Indonesian islands until it was recently found to be the cause of outbreaks that occurred in several Australian states in early 2022. Given the limited availability of information, the vector range for JEV GIV remains unknown; thus, understanding this range could prove invaluable for future prevention efforts in new areas. Herein, we experimentally exposed four mosquito colonies originated from various countries with no previous reports of GIV to JEV GIV strain 19CxBa-83-Cv, which was isolated from Theobald collected in Bali in 2019.

Extent and Nature of Television Food and Nonalcoholic Beverage Marketing in 9 Asian Countries: Cross-Sectional Study Using a Harmonized Approach.

Background: Rising childhood obesity rates in Asia are adding risk for the future adult burden of obesity and noncommunicable diseases. Weak policies across most Asian countries enable unrestricted marketing of obesogenic foods and beverages to children. Television is the common medium for food marketing to reach this audience.

Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: A randomised, comparator-controlled, phase 2 trial.

Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and lower-middle-income countries is needed. NDV-HXP-S is an inactivated egg-based recombinant Newcastle disease virus vaccine expressing the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A public sector manufacturer in Vietnam assessed the immunogenicity of NDV-HXP-S (COVIVAC) relative to an authorized vaccine.

Development of a loop-mediated isothermal amplification method for the rapid detection of Clostridium botulinum serotypes E and F.

Background: Botulinum neurotoxin serotypes E and F (BoNT/E and BoNT/F) produced by the bacteria Clostridium botulinum (C. botulinum) found in a wide variety of foods cause poisoning in humans with high mortality rates. Mouse bioassays (MBAs), the gold standard method for BoNT detection, have a low detection limit; however, require experienced personnel and take a long time to obtain results.

Rotavirus vaccine effectiveness stratified by national-level characteristics: an introduction to the 24-country MNSSTER-V Project, 2007-2023.

Background: Rotavirus vaccines are moderately protective against illness in high mortality settings compared with low mortality settings. Vaccine effectiveness (VE) evaluations may clarify our understanding of these disparities, but estimates among key subpopulations and against rare outcomes are not available in many analyses due to sample size. We combined 25 datasets from test-negative design case-control evaluations in 24 countries that enrolled children with medically-attended diarrhea, laboratory-confirmed rotavirus stool testing, and documented vaccination status.

Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam.

Background: After pneumococcal disease and colonization have been controlled through vaccination campaigns, a reduced pneumococcal conjugate vaccine (PCV) schedule may be sufficient to sustain that control at reduced costs.

Methods: We investigated whether a single primary dose and booster dose (1p+1) of the 10-valent PCV (PCV10) would be noninferior to alternative dose schedules in sustaining control of carriage of pneumococcal serotypes included in the vaccine. In Nha Trang, Vietnam, an area in which PCV had not been used previously, a PCV10 catch-up campaign was conducted in which the vaccine was offered to children younger than 3 years of age, after which a cluster-randomized trial was conducted in which children received PCV10 at 2, 3, and 4 months of age (3p+0 group); at 2, 4, and 12 months of age (2p+1 group); at 2 and 12 months of age (1p+1 group); or at 12 months of age (0p+1 group).

Non-typhoidal in humans in India, Vietnam, Bangladesh and Sri Lanka: a systematic review.

Objectives: Non-typhoidal (NTS) commonly causes a self-limiting illness but invasive disease (iNTS) can be life-threatening. Antimicrobial resistance (AMR) increases the risk of mortality. This systematic review aimed to estimate the proportion of NTS isolated in those attending healthcare services, serovar burden, AMR, serovar-specific AMR, and case fatality rate (CFR) in India, Bangladesh, Sri Lanka and Vietnam.

Understanding Parental Decision-Making and Determinants of COVID-19 Vaccination for Children in Vietnam: A Cross-Sectional Online Survey.

Background/objectives: In Vietnam, COVID-19 vaccination campaigns for children have encountered numerous challenges due to acceptance issues among parents. This study aimed to assess parental decision-making and identify factors influencing their decision to vaccinate their children against COVID-19.

Methods: This was a cross-sectional online survey conducted between April and May 2023 among parents of children aged 6-17 years enrolled in urban and rural schools in Thai Nguyen province, Vietnam.

In vitro antimicrobial and antioxidant activities of bioactive compounds extracted from Streptomyces africanus strain E2 isolated from Moroccan soil.

This study aimed to isolate Streptomyces sp. from Moroccan terrestrial ecosystems and identify bioactive compounds through GC-MS analysis. Antimicrobial activity was assessed against various pathogenic microorganisms including Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922 and Candida albicans ATCC 60193, and multi-drug resistant strains comprising Listeria monocytogenes, Klebsiella pneumoniae 19K 929, Proteus sp.

The APOBEC3G gene rs2294367(C>G) variant is associated with HIV-1 infection in Moroccan subjects.

The APOBEC3G gene is one of the most important host factors thathas beenfound previously associated withHIV infection and AIDS progression. The host's susceptibility to viral infectionmay be influenced by any APOBEC3G genetic variation.The main aim of thecurrent study was to investigate the association of three SNPs in the APOBEC3G gene (rs8177832, rs35228531, and rs2294367) respectively, with disease outcomes in Moroccan HIV-1 infected patients.

Genomic epidemiology and resistant genes of clinical strains in Vietnamese hospitals.

is a common cause of multidrug-resistant (MDR) nosocomial infections worldwide, including Vietnam. Analysis of crucial genetic factors may link to epidemiological characteristics and antibiotic resistance of clinical strains in Vietnamese hospitals. Fifty-one .

Clinical Features and Treatment Outcomes of Influenza-Associated Encephalitis and Encephalopathy: A Study on 16 Children in Vietnam.

. This study aims to report clinical features and treatment outcomes of 16 cases diagnosed with post-influenza encephalopathy/encephalitis. .

In Vitro Inhibitory Effect of Berberine Against Rotavirus.

Although berberine (BBR) is well known as an active constituent in traditional medicines used in the treatment of gastrointestinal diseases, its potential against viral gastroenteritis has not been specifically reported. This study aims to investigate the antiviral activity of BBR against rotavirus and evaluate its cytotoxicity and pharmacological efficacies, including antioxidant and anti-inflammatory activities in vitro. Using ultraviolet-visible absorption spectroscopy, the saturation concentration of BBR was determined as 2261 μg/mL, indicating that BBR is a poor water-soluble compound.

Percarbonate-periodate system: A novel and efficient "oxidant-oxidant" strategy for selective oxidation of micropollutants in water.

The development of effective and selective oxidation technology in complex water matrices is crucial for water ecological security. This study reports for the first time the synergistic use of "oxidant-oxidant" about sodium percarbonate (SPC) and periodate (PI) to selectively degrade organic micropollutants. The SPC/PI system showed degradation rates of 0.

Persistent organochlorine pollutants in different bivalve species from central Vietnamese coasts: Concentrations, profiles, and biota-sediment accumulation factors.

Concentrations of typical persistent organochlorine pollutants (POCPs) like organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in five bivalve species collected from central Vietnamese coasts were determined to provide insights into spatial distribution and bioaccumulation characteristics of these substances. Concentrations of pollutants decreased in the order: PCBs (median 14.6; range 1.

Influenza vaccine allocation in tropical settings under constrained resources.

Influenza virus seasonality, synchronicity, and vaccine supply differ substantially between temperate and tropical settings, and optimal vaccination strategy may differ on this basis. Many national vaccine recommendations focus on high-risk groups, elderly populations, and healthcare workers despite previous analyses demonstrating broad benefits to vaccinating younger high-contact age groups. In this study, we parameterized an age-structured nonseasonal asynchronous epidemiological model of influenza virus transmission for a tropical low-income setting.