753 results match your criteria: "National Institute of Epidemiology[Affiliation]"

Background: In July 2021, the Alappuzha district in Kerala, India, reported an unexpected number of acute gastroenteritis (772) cases (Outbreak A). On October 10, 2021, a university in Wayanad, Kerala, reported 25 acute gastroenteritis cases (Outbreak B). We described both the outbreaks and determined the agent, source and risk factors.

View Article and Find Full Text PDF
Article Synopsis
  • Non-tobacco products (NTP) are gaining popularity as alternatives to traditional tobacco, but there's growing concern about their potential health risks, particularly regarding oral, esophageal, and pharyngeal cancers.
  • A systematic review analyzed 49 studies involving over 132,000 participants, showing a significant increase in cancer risk associated with NTP use, with odds ratios indicating a 5x risk for oral cancer and 3x for esophageal cancer.
  • The review emphasizes the need for greater regulation and awareness, as NTP use accounts for a considerable proportion of cancer cases, urging the inclusion of NTP data in national health surveys to better address the issues in high-risk groups.
View Article and Find Full Text PDF

Introduction: The Siddha system of medicine (SSM) is one of the Indian Systems of Medicine (ISM). In recent times, it has received adequate support from the Indian Ministry of Ayush. Like many such indigenous systems of medicine globally, the SSM is based on its own theoretical principles, philosophy, and methods of practice.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed global, regional, and national trends in injury burden and identified risk factors contributing to injuries using data from the GBD 2019.
  • In 2019, there were approximately 713.9 million injury incidents and 4.3 million injury-related deaths globally, with low bone mineral density emerging as the leading risk factor.
  • The findings emphasize the need for effective global injury prevention policies by highlighting the persistent impact of injuries on global health.
View Article and Find Full Text PDF

Background: Enteric infections are hypothesized to be associated with intussusception in children. A small increase in intussusception following rotavirus vaccination has been seen in some settings. We conducted post-marketing surveillance for intussusception following rotavirus vaccine, Rotavac introduction in India and evaluated association of intussusception with enteric pathogens.

View Article and Find Full Text PDF

Background: Exposure to extreme weatherly events potentially develops mental disorders among affected individuals.

Aim: To synthesize the burden of mental disorders following impact of extreme weather events in South-east Asian (SEA) countries.

Methods: Proposal was registered in PROSPERO register [CRD42023469788] and reported as per PRISMA-2020 guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • Inguinal hernia surgeries often lead to significant postoperative pain, which can result in chronic pain if not properly managed.
  • A study involving 60 patients examined three ultrasound-guided quadratus lumborum block approaches (transmuscular, lateral, and posterior) to assess their effectiveness in pain management after the surgery.
  • Results showed that the transmuscular approach was the most effective, leading to lower pain medication needs and better pain scores, while all techniques had similar patient satisfaction and no adverse effects reported.
View Article and Find Full Text PDF

Identifying interventions that improve medication safety & rational use of medicines in India.

Indian J Med Res

May 2024

Clinical Studies and Trials Unit, Division of Development Research, Indian Council of Medical Research, New Delhi, India.

Article Synopsis
  • Many people end up in the hospital because of problems with their medicines, and in India, a lot of the medicines used aren’t really necessary, making health costs high.* -
  • In 2022, a National Task Force was set up in India to find better ways to use medicines safely and wisely, by asking experts for research ideas.* -
  • They collected 209 unique ideas from 190 people and had experts rank these ideas, with the best ones focusing on things like using antibiotics properly and safely managing medicine for older patients.*
View Article and Find Full Text PDF
Article Synopsis
  • PGx factors play a crucial role in how patients react to antipsychotic medications, prompting a systematic review to compare PGx-assisted treatment with standard care in schizophrenia.
  • Five randomized controlled trials (RCTs) were analyzed, all showing high risk of bias, with mixed findings on safety, efficacy, and medication adherence.
  • The meta-analysis highlighted significant differences in side effects and symptom severity between the two treatment methods, but overall, the evidence is limited and inconsistent, indicating a need for further research.
View Article and Find Full Text PDF
Article Synopsis
  • * Recent efforts to stop smoking haven't been put into action yet, and it’s important to see what could happen if smoking rates stay the same or improve.
  • * Researchers used models to predict health outcomes by 2050 based on different scenarios of smoking rates, showing that cutting smoking could greatly improve health and life expectancy.
View Article and Find Full Text PDF
Article Synopsis
  • End-stage kidney disease (ESKD) requires kidney replacement therapies (KRTs) like kidney transplantation (KT), hemodialysis (HD), and peritoneal dialysis (PD) for survival, but access to these treatments is often limited due to high costs.
  • A systematic review analyzed economic evaluations and comparisons of KRTs across thirteen studies, revealing that KT was generally the most cost-effective option, while HD was the least effective and most expensive compared to PD.
  • The review emphasizes that enhancing access to both KT and PD could significantly improve treatment options for ESKD patients, especially in high-income countries.
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the prevalence of dog bites and human rabies deaths in India, where a significant portion of global rabies cases occurs, aiming to assess progress toward a 2030 elimination goal.
  • - A nationwide survey found that in a year, there were approximately 9.1 million dog bites in India, with 20.5% of those bitten not receiving necessary anti-rabies vaccinations (ARV).
  • - The study estimates around 5,726 human rabies deaths annually, indicating that, despite some progress, there's still a critical need for improved vaccination and prevention strategies.
View Article and Find Full Text PDF
Article Synopsis
  • * The use of protamine to reverse heparin after TAVR did not show a significant reduction in major bleeding compared to the control group, with similar rates of life-threatening bleeding and other complications.
  • * While protamine seems safe post-TAVR and doesn't increase stroke risk, more research is needed to confirm its effectiveness in reducing bleeding through a larger, multicentric study.
View Article and Find Full Text PDF
Article Synopsis
  • Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
  • In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
  • There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
View Article and Find Full Text PDF

Projected impact of fast-tracking of anti-retroviral treatment coverage on vertical transmission of HIV in India.

PLOS Glob Public Health

September 2024

National AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.

One of the five high-level goals under Phase V of the National AIDS and STD Control Programme (NACP) of the Government of India is the elimination of vertical transmission of HIV. In this paper, we estimate the potential impact of maintaining and enhancing the anti-retroviral treatment under the NACP in terms of averting new infections and vertical transmission rates vis-à-vis no intervention scenario. We used India's HIV Estimates 2022 models to create treatment coverage scenarios of no interventions, status quo, business as usual, on-track and fast-track scenarios from 2023 to 2030.

View Article and Find Full Text PDF

We conducted a systematic review of analytical epidemiological studies to assess the association between ChAdOx1-S vaccination and thromboembolic, thrombocytopenic, and hemorrhagic events. We searched Medline, Embase, Google Scholar, WHO-COVID-19 database, and medRxiv for studies evaluating the association between ChAdOx1-S and vascular events. Primary outcomes of interest were cerebral venous sinus thrombosis, peripheral venous thrombosis (PVT), and thrombocytopenia.

View Article and Find Full Text PDF

Background: The National TB elimination programme (NTEP) is facilitating sub-national certification of "TB Free" status with benchmarks at every 20% reduction in incidence from the baseline of 2015. Drug consumption/sale is essential criteria to claim for the award. During the certification process in 10 districts of Madhya Pradesh in 2022, it was found that Nikshay Aushadhi (a web-based supply chain management portal) entries were incomplete or vacant in most of the districts and it was observed that quarterly drug requests were not sent using Nikshay Aushadhi.

View Article and Find Full Text PDF

BCG vaccination is known to be safe in infants and a part of immunization schedule in high tuberculosis (TB) burden countries. In the conquest to bring down the severity of the COVID 19 pandemic, many drugs were repurposed in research mode including BCG vaccination/revaccination in various populations. We did a study among the elderly population (>60 years of age) to assess the role of BCG revaccination in preventing the severity of COVID 19 disease.

View Article and Find Full Text PDF

Objectives: To estimate the prevalence and identify the factors associated with undiagnosed hypertension in India.

Study Design: A secondary data analysis using the National Family Health Survey (NFHS-5) covering the period 2019-2021.

Methods: Information on hypertension among individuals aged 15-49 years was extracted from the survey dataset.

View Article and Find Full Text PDF

Objective: To investigate the prevalence of problematic internet use (PIU) among adolescents and determine the associated factors contributing to PIU.

Methods: In April/May 2023, a cross-sectional study was conducted among adolescents studying in grades 9 to 12 in government and private non-residential schools in Western Tamil Nadu, India. Participants completed a semi-structured questionnaire assessing demographic characteristics, behavioral patterns, and internet usage.

View Article and Find Full Text PDF
Article Synopsis
  • Acute respiratory infections (ARIs) are a major global health issue, particularly affecting children under five, with 95% of deaths occurring in developing countries.
  • A study conducted at ICMR-RMRC in Gorakhpur, Uttar Pradesh, found that 4% of children with ARI tested positive for Human Metapneumovirus (hMPV), leading to a mortality rate of 25% among infected patients.
  • The research emphasizes the urgent need for routine testing for hMPV in the region and suggests further investigation into the virus's impact and characteristics.
View Article and Find Full Text PDF

Background: The dynamicity and mobility of the population in a mass gathering setting pose a challenge to traditional disease surveillance methods and strain the local health services. Velankanni is one of the most sacred Christian pilgrimage places located in Nagapattinam, Tamil Nadu, India. We participated in the Velankanni festival to describe the public health preparedness, surveillance, and response activities carried out during the festival.

View Article and Find Full Text PDF

Background: Indian subcontinent being an important region in the fight to eliminate cholera needs better cholera surveillance. Current methods miss most infections, skewing disease burden estimates. Triangulating serosurvey data, clinical cases, and risk factors could reveal India's true cholera risk.

View Article and Find Full Text PDF