305 results match your criteria: "National Institute of Cancer Prevention and Research.[Affiliation]"
Skin Cancer Concerns in People of Color: Risk Factors and Prevention.
Asian Pac J Cancer Prev
December 2016
1Division of Molecular Cytology, National Institute of Cancer Prevention and Research (Formerly, Institute of Cytology and Preventive Oncology) (ICMR) Department of Health Research (Govt. of India),Noida, India. Email:
Background: Though people of color (POC) are less likely to become afflicted with skin cancer, they are much more likely to die from it due to delay in detection or presentation. Very often, skin cancer is diagnosed at a more advanced stage in POC, making treatment difficult.The purpose of this research was to improve awareness regarding skin cancers in people of color by providing recommendations to clinicians and the general public for early detection and photo protection preventive measures.
View Article and Find Full Text PDFEffects of A.marina-Derived Isoquercitrin on TNF-Related Apoptosis-Inducing Ligand Receptor (TRAIL-R) Expression and Apoptosis Induction in Cervical Cancer Cells.
Appl Biochem Biotechnol
June 2017
Division of Molecular Genetics & Biochemistry, National Institute of Cancer Prevention and Research, I-7, Sector - 39, Noida, Uttar Pradesh, 201 301, India.
TNF-related apoptosis-inducing ligand (TRAIL) is an anticancer agent, which has greater apoptosis inducing capacity, but most of the cancer cells become resistant to TRAIL-induced apoptosis. The combined treatment of TRAIL with natural products could restore the cancer cell sensitivity to recombinant human TRAIL (rhTRAIL) protein and might enhance the TNF-related apoptosis-inducing ligand receptor (TRAIL-R) expression. This investigation was aimed to isolate flavonoids from leaves of Avicennia marina and evaluate their potential for sensitization of rhTRAIL in human cervical cancer cells (SiHa).
View Article and Find Full Text PDFSpiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.
Top Curr Chem (Cham)
February 2017
Division of Molecular Cytology, Department of Health Research (Govt. of India), National Institute of Cancer Prevention and Research (ICMR), Noida, India.
As a result of the toxicity of currently available anticancer drugs and the inefficiency of chemotherapeutic treatments, the design and discovery of effective and selective antitumor agents continues to be a hot topic in organic medicinal chemistry. Targeted therapy is a newer type of cancer treatment that uses drugs designed to interfere with specific molecules necessary for tumor growth and progression. This review explains the mechanism of regulation of p53 (tumor suppressor protein) by MDM2 and illustrates the role of targeting p53-MDM2 protein-protein interaction using small molecules as a new cancer therapeutic strategy.
View Article and Find Full Text PDFTobacco-related cancers in India: A review of incidence reported from population-based cancer registries.
Indian J Med Paediatr Oncol
October 2016
Division of Epidemiology and Biostatistics, National Institute of Cancer Prevention and Research, Indian Council of Medical Research, I-7, Sector-39, Noida, Uttar Pradesh, India.
Background: Tobacco related cancers (TRC) account for major share of all cancers and updated of incidence data are helpful in policy changes. The aim was to present an update of TRCs on age-adjusted incidence data and corresponding lifetime risk of developing TRC for different regions of the country.
Methods: The data for this study were obtained from published reports of 25 population-based cancer registries (PBCRs) in India.