Extreme-ultraviolet multilayer coatings with high spectral purity for solar imaging.

Future solar experiments designed to perform solar plasma diagnostics will also be based on extreme-ultravilet observations. Multilayer (ML) optics are essential in this spectral region since these coatings have high reflectivity at normal incidence. Typically, the reflectivity curve of a ML coating has a small but finite bandwidth, and this can be a serious drawback when several spectral lines fall within the bandwidth.

Realization and characterization of an XUV multilayer coating for attosecond pulses.

The experimental characterization of an aperiodic reflecting multilayer (ML) structure designed to reflect and compress attosecond pulses in the extreme ultraviolet spectral region is presented. The MLs are designed for the 75-105 eV spectral interval with suitable reflectance and phase behavior, in particular high total spectral reflectivity coupled with very wide bandwidth and spectral phase compensation. The experimental phase behavior of the multilayer has been obtained through electron photoemission signal using an innovative method that is presented and discussed in this paper.

Sample preparation for the quick sizing of metal nanoparticles by atomic force microscopy.

Two alternative pretreatment methods for depositing metal nanoparticles on mica for atomic force microscopy (AFM) imaging are presented. The treated substrates are flat and clean, thus they are amenable of use to characterize very small nanoparticles. The methods do not require any instrumentation or particular expertise.

The dynamic properties of an intramolecular transition from DNA duplex to cytosine-thymine motif triplex.

We here report that the formation and breakdown of an intramolecular cytosine-thymine (CT) motif DNA triple-helix can be performed repeatedly, quickly and independently of its local concentration without performance reduction over successive cycles; as a consequence, we propose that this set of characteristics makes the DNA duplex-triplex transition an ideal candidate to power simple nanometer-scale devices capable of maintaining effective performance regardless of their local concentration.

Single molecule studies of RNA secondary structure: AFM of TYMV viral RNA.

Nowadays, the development of experimental procedures for the determination of the secondary structure of RNA molecules is taking advantage of the novel single-molecule probing and imaging techniques. We report a method for the mapping of the secondary structure of RNA molecules spread on a flat surface by means of the atomic force microscope. Globular domains comprising groups of RNA secondary and tertiary structure elements separated by unstructured domains can be discerned in the micrographs and their position along the molecule contour can be measured directly on unstained specimens.

Observation of optical spatial solitons in a highly nonlocal medium.

We report on the observation and quantitative assessment of self-trapped pulsating beams in a highly nonlocal nonlinear regime. The experiments were conducted in nematic liquid crystals and allow a meaningful comparison with the prediction of a scalar theory in the perturbative limit, while addressing the need for beyond-paraxial analytical treatments.

Static and dynamic water molecules in Cu,Zn superoxide dismutase.

Understanding protein hydration is a crucial, and often underestimated issue, in unraveling protein function. Molecular dynamics (MD) computer simulation can provide a microscopic description of the water behavior. We have applied such a simulative approach to dimeric Photobacterium leiognathi Cu,Zn superoxide dismutase, comparing the water molecule sites determined using 1.

Structure and stability of the insulin dimer investigated by molecular dynamics simulation.

Molecular dynamics simulation indicates that the dynamical behaviour of the insulin dimer is asymmetric. Atomic level knowledge of the interaction modes and protein conformation in the solvation state identifies dynamical structures, held by hydrogen bonds that stabilize, mainly in one monomer, the interaction between the chains. Dynamic cross-correlation analysis shows that the two insulin monomers behave asymmetrically and are almost independent.

Flow Rate Profiler: an instrument to measure blood velocity profiles.

In this paper we present Flow Rate Profiler (FRP), an instrument for measuring the blood velocity by means of ultrasound-based techniques. The velocity is directly related to the shear rate, which is in turn proportional to the shear stress, a parameter expressing the pressure exerted by the blood on the vessel walls. The knowledge of this value is important in medicine to establish the state of the vessels, directly related to vascular diseases.