375 results match your criteria: "National Institute for Nuclear Physics[Affiliation]"

We report on the first search for electron-muon lepton flavor violation (LFV) in the decay of a b quark and b antiquark bound state. We look for the LFV decay ϒ(3S)→e^{±}μ^{∓} in a sample of 118 million ϒ(3S) mesons from 27  fb^{-1} of data collected with the BABAR detector at the SLAC PEP-II e^{+}e^{-} collider operating with a 10.36 GeV center-of-mass energy.

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Among the first clinical symptoms of the SARS-CoV-2 infection is olfactory−gustatory deficit; this continues for weeks and, in some cases, can be persistent. We prospectively evaluated 162 patients affected by COVID-19 using a visual analogue scale (VAS) for nasal and olfactory−gustatory symptoms. Patients were checked after 7, 14, 21, 28, 90, and 180 days.

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Is the Cu production worldwide feasible for expanding preclinical and clinical studies? How can we face the ingrowing demands of this emerging and promising theranostic radionuclide for personalized therapies? This review looks at the different production routes, including the accelerator- and reactor-based ones, providing a comprehensive overview of the actual Cu supply, with brief insight into its use in non-clinical and clinical studies. In addition to the most often explored nuclear reactions, this work focuses on the Cu separation and purification techniques, as well as the target material recovery procedures that are mandatory for the economic sustainability of the production cycle. The quality aspects, such as radiochemical, chemical, and radionuclidic purity, with particular attention to the coproduction of the counterpart Cu, are also taken into account, with detailed comparisons among the different production routes.

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Article Synopsis
  • The "Blue Sky Radiomics" study aims to evaluate a specific radiomic signature in patients with stage III unresectable non-small cell lung cancer (NSCLC) receiving treatment involving chemoradiotherapy and immunotherapy.
  • The study involved analyzing primary lung tumors on CT scans taken before and after treatment, utilizing various scanners and protocols to assess the consistency of radiomic features extracted from the scans.
  • The results showed that initial acquisition parameters significantly affected 76% of the radiomic features, but after applying a harmonization process, the features became independent of these protocols, highlighting the importance of harmonization for ensuring reliable radiomic data.
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Charge breeders: Development of diagnostic tools to probe the underlying physics.

Rev Sci Instrum

February 2022

European Organization for Nuclear Research, Esplanade des Particules 1, 1211 Geneva 23, Switzerland.

Charge breeders were developed more than 20 years ago in the context of radioactive ion beam (RIB) production. The main goal is to boost the charge state of a singly charged RIB to a higher value matching the A/Q of a post-accelerator. In that way, the RIB produced at some tens of keV can efficiently be accelerated to energies in a range of few MeV/u up to several tens of MeV/u, which is of interest for nuclear structure and nuclear astrophysics experiments.

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The lockdown restrictions, as a first solution to contain the spread of the COVID-19 pandemic, have affected everyone's life and habits, including the time spent at home. The latter factor has drawn attention to indoor air quality and the impact on human health, particularly for chemical pollutants. This study investigated how the increasing time indoor influenced exposure to natural radioactive substances, such as radon gas.

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The Bologna Archaeological Museum, in cooperation with prestigious Italian universities, institutions, and independent scholars, recently began a vast investigation programme on a group of Egyptian coffins of Theban provenance dating to the first millennium BC, primarily the 25th-26th Dynasty ( 746-525 BC). Herein, we present the results of the multidisciplinary investigation carried out on one of these coffins before its restoration intervention: the anthropoid wooden coffin of Un-Montu (Inv. MCABo EG1960).

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Purpose: To comprehensively describe the treatment of mediastinal lymphoma by pencil beam scanning (PBS) proton therapy.

Methods: Fourteen patients underwent PBS proton treatment in a supine position in deep inspiration breath-hold (DIBH). Three DIBH computed tomography (CT) scans were acquired for each patient to delineate the Internal Target Volume (ITV).

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Learning residual motion correction for fast and robust 3D multiparametric MRI.

Med Image Anal

April 2022

Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland; Department of Computer Science, Technical University of Munich, Garching, Germany.

Voluntary and involuntary patient motion is a major problem for data quality in clinical routine of Magnetic Resonance Imaging (MRI). It has been thoroughly investigated and, yet it still remains unresolved. In quantitative MRI, motion artifacts impair the entire temporal evolution of the magnetization and cause errors in parameter estimation.

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Small average differences in the left-right asymmetry of cerebral cortical thickness have been reported in individuals with autism spectrum disorder (ASD) compared to typically developing controls, affecting widespread cortical regions. The possible impacts of these regional alterations in terms of structural network effects have not previously been characterized. Inter-regional morphological covariance analysis can capture network connectivity between different cortical areas at the macroscale level.

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Collider searches for dark sectors, new particles interacting only feebly with ordinary matter, have largely focused on identifying signatures of new mediators, leaving much of dark sector structures unexplored. In particular, the existence of dark matter bound states (darkonia) remains to be investigated. This possibility could arise in a simple model in which a dark photon (A^{'}) is light enough to generate an attractive force between dark fermions.

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The chemical composition of 48 glass finds from Histria and Tomis, Romania, chiefly dated to the 1st-4th c. AD, was determined using prompt gamma activation analysis (PGAA) at the Budapest Neutron Centre (BNC). Most fragments have composition typical for the Roman naturally colored blue-green-yellow (RNCBGY) glass; Mn-colorless, Sb-colorless, and Sb-Mn colorless glass finds were evidenced, too.

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Plastic and microplastic pollutions are known to be widespread across the planet in all types of environments. However, relatively little about microplastic quantities in the deeper areas of the oceans is known, due to the difficulty to reach these environments. In this work, we present an investigation of microplastic (<5 mm) distribution performed in the bottom sediments of the abyssal plain off the coast and the canyon of Toulon (France).

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Cerebral venous outflow is investigated in the diagnosis of heart failure through the monitoring of jugular venous pulse, an indicator to assess cardiovascular diseases. The jugular venous pulse is a weak signal stemming from the lying internal jugular vein and often invasive methodologies requiring surgery are mandatory to detect it. Jugular venous pulse can also be extrapolated via the ultrasound technique, but it requires a qualified healthcare operator to perform the examination.

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Micro- and Nano-Scales Three-Dimensional Characterisation of Softwood.

J Imaging

December 2021

X-ray Tomography Group, Swiss Light Source, Paul Scherrer Institute, 5232 Villigen, Switzerland.

Understanding the mechanical response of cellular biological materials to environmental stimuli is of fundamental importance from an engineering perspective in composites. To provide a deep understanding of their behaviour, an exhaustive analytical and experimental protocol is required. Attention is focused on softwood but the approach can be applied to a range of cellular materials.

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Radiographic imaging with muons, also called Muography, is based on the measurement of the absorption of muons, generated by the interaction of cosmic rays with the earth's atmosphere, in matter. Muons are elementary particles with high penetrating power, a characteristic that makes them capable of crossing bodies of dimensions of the order of hundreds of meters. The interior of bodies the size of a pyramid or a volcano can be seen directly with the use of this technique, which can rely on highly segmented muon trackers.

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Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are generally easy to identify, the process of manually annotating cells is sometimes subject to fatigue errors and suffers from arbitrariness due to the operator's interpretation of the borderline cases. We propose a Deep Learning approach that exploits a fully-convolutional network in a binary segmentation fashion to localize the objects of interest.

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Enhancing the impact of Artificial Intelligence in Medicine: A joint AIFM-INFN Italian initiative for a dedicated cloud-based computing infrastructure.

Phys Med

November 2021

Department Biomedical Experimental and Clinical Science "Mario Serio", University of Florence, 50134 Florence, Italy; INFN, Florence Division, 50134 Florence, Italy.

Artificial Intelligence (AI) techniques have been implemented in the field of Medical Imaging for more than forty years. Medical Physicists, Clinicians and Computer Scientists have been collaborating since the beginning to realize software solutions to enhance the informative content of medical images, including AI-based support systems for image interpretation. Despite the recent massive progress in this field due to the current emphasis on Radiomics, Machine Learning and Deep Learning, there are still some barriers to overcome before these tools are fully integrated into the clinical workflows to finally enable a precision medicine approach to patients' care.

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Molecular Weight Tuning of Organic Semiconductors for Curved Organic-Inorganic Hybrid X-Ray Detectors.

Adv Sci (Weinh)

January 2022

Advanced Technology Institute, Department of Electrical and Electronic Engineering, University of Surrey, Guildford, Surrey, GU2 7XH, UK.

Curved X-ray detectors have the potential to revolutionize diverse sectors due to benefits such as reduced image distortion and vignetting compared to their planar counterparts. While the use of inorganic semiconductors for curved detectors are restricted by their brittle nature, organic-inorganic hybrid semiconductors which incorporated bismuth oxide nanoparticles in an organic bulk heterojunction consisting of poly(3-hexylthiophene-2,5-diyl) (P3HT) and [6,6]-phenyl C71 butyric acid methyl ester (PC BM) are considered to be more promising in this regard. However, the influence of the P3HT molecular weight on the mechanical stability of curved, thick X-ray detectors remains less well understood.

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Purpose: To assess the dosimetric advantages of apertures in intracranial single fraction proton radiosurgery.

Materials And Methods: Six neuroma and 10 meningioma patients were investigated. For each patient, six plans were computed, with two spot spacing and three aperture settings (no apertures, 5 and 8 mm margin between aperture and clinical target volume [CTV]).

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Laniakea@ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based service.

BMC Bioinformatics

November 2021

Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council (CNR), Via Giovanni Amendola 122/O, 70126, Bari, Italy.

Background: Improving the availability and usability of data and analytical tools is a critical precondition for further advancing modern biological and biomedical research. For instance, one of the many ramifications of the COVID-19 global pandemic has been to make even more evident the importance of having bioinformatics tools and data readily actionable by researchers through convenient access points and supported by adequate IT infrastructures. One of the most successful efforts in improving the availability and usability of bioinformatics tools and data is represented by the Galaxy workflow manager and its thriving community.

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Professor Henry Tye () is a world-renowned expert in theoretical particle physics, string theory and cosmology. He was recently the IAS Professor at the Jockey Club Institute for Advanced Study (IAS) and the Hong Kong University of Science and Technology (HKUST), and is the Horace White Professor of Physics (Emeritus) at Cornell University. He has a lot of experience in research status in both China and the United States.

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Cyclotron-based radionuclides production by using solid targets has become important in the last years due to the growing demand of radiometals, e.g., Ga, Zr, Sc, and Mn.

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Relevance of Internal Bremsstrahlung photons from Y decay: an experimental and Monte Carlo study.

Phys Med

October 2021

Section of Radiological Sciences, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy; INFN, National Institute for Nuclear Physics, Section of Catania, Italy.

Internal Bremsstrahlung (IB) is a continuous electromagnetic radiation accompanying beta decay; however, this process is not considered in radiation protection studies, particularly when estimating exposure from beta-decaying radionuclides. The aims of the present work are: i) to show that neglecting the IB process in Monte Carlo (MC) simulation leads to an underestimation of the energy deposited in a ionization chamber, in the case of a high-energy pure beta emitter such as Yttrium-90 (Y), and ii) to determine the most reliable choice of source term for Y IB to be used in MC simulations. For this radionuclide, commonly employed in nuclear medicine and radiochemistry applications, experimental data acquired with a well ionization chamber have been compared with Monte Carlo (MC) calculations carried out in the GAMOS framework.

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