Earlier onset of North Atlantic hurricane season with warming oceans.

Numerous Atlantic basin tropical cyclones have recently developed prior to the official start of hurricane season, including several pre-season landfalls in the continental United States. Pre-season and early-season tropical cyclones disproportionately affect populated landmasses, often producing outsized precipitation impacts. Here we show a significant trend towards earlier onset of tropical cyclone activity in the North Atlantic basin, with threshold dates of the first three percentiles of accumulated cyclone energy shifting earlier at a rate exceeding five days decade since 1979, even correcting for biases in climatology due to increased detection of short-lived storms.

Changes in Atlantic major hurricane frequency since the late-19th century.

Atlantic hurricanes are a major hazard to life and property, and a topic of intense scientific interest. Historical changes in observing practices limit the utility of century-scale records of Atlantic major hurricane frequency. To evaluate past changes in frequency, we have here developed a homogenization method for Atlantic hurricane and major hurricane frequency over 1851-2019.

Bone Marrow Mesenchymal Stem Cell-Derived Hepatocyte-Like Cell Exosomes Reduce Hepatic Ischemia/Reperfusion Injury by Enhancing Autophagy.

Ischemia/reperfusion (I/R) injury remains a major problem in liver transplantation. I/R causes inflammatory cytokine release, apoptosis, and necrosis. Bone marrow-mesenchymal stem cells (BM-MSCs) can differentiate into hepatocytes in vivo, and differentiation further increases when hepatocytes are damaged.