125 results match your criteria: "National Hospital Organization Murayama Medical Center[Affiliation]"

Article Synopsis
  • This study analyzed 389 patients aged 65 and older with cervical spinal cord injury (CSCI) but no bone injury to assess the effects of diabetes on neurological recovery.
  • The research found that there were no significant differences in neurological outcomes between diabetic patients and those without diabetes at 6 months post-injury.
  • Additionally, moderate-severe diabetes did not adversely impact recovery, suggesting that diabetic patients had similar improvements in neurological function as their nondiabetic counterparts.
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Article Synopsis
  • A retrospective multicenter study was conducted in Japan to assess the influence of preoperative neck pain on clinical outcomes after posterior decompression surgery for cervical ossification of the posterior longitudinal ligament (OPLL).
  • The study involved 90 patients followed for at least two years, who were grouped based on the presence or absence of preoperative neck pain, but the two groups showed no significant demographic or outcome differences.
  • Both groups improved post-surgery according to the Japanese orthopedic association (JOA) scores, but lower JOA scores and larger cervical angles in the no preoperative pain group were linked to higher chances of developing postoperative neck pain.
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Article Synopsis
  • This study analyzed the surgical outcomes of posterior decompression for cervical ossification of the posterior longitudinal ligament (OPLL), comparing procedures performed by board-certified spine (BCS) surgeons and non-board-certified (NBCS) surgeons.
  • It included 203 patients monitored for at least one year, measuring their clinical outcomes pre-surgery and after, focusing on factors like surgery duration, blood loss, and post-operative recovery.
  • Results showed no significant differences in surgical metrics or recovery outcomes between BCS and NBCS groups, indicating that surgery performed by well-trained junior surgeons under supervision is safe and effective.
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Article Synopsis
  • * This study investigated the effects of high-molecular-weight hyaluronan (HA) on young rats that underwent ovariectomy (OVX) to induce osteoporosis, with some receiving HA injections and others receiving saline.
  • * Results showed that the OVX-HA group had improved bone health indicators compared to the saline group, with bone formation and resorption metrics closer to those of healthy control rats, highlighting the potential of HA in treating osteoporosis in young adults.
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Impact of malnutrition on mortality and neurological recovery of older patients with spinal cord injury.

Sci Rep

March 2024

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

This retrospective cohort study established malnutrition's impact on mortality and neurological recovery of older patients with cervical spinal cord injury (SCI). It included patients aged ≥ 65 years with traumatic cervical SCI treated conservatively or surgically. The Geriatric Nutritional Risk Index was calculated to assess nutritional-related risk.

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Neurological recovery rate and predictive factors of incomplete AIS grade C spinal cord injury in the older aged population.

Spinal Cord

April 2024

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Study Design: Retrospective cohort study.

Objectives: To define the prognosis and predictive factors for neurological improvement in older patients with incomplete spinal cord injury (SCI) of American Spinal Injury Association Impairment Scale grade C (AIS-C).

Settings: Multi-institutions in Japan.

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Purpose: The importance of coronal alignment is unclear, while the importance of sagittal alignment in the treatment of adult patients with spinal deformities is well described. This study sought to elucidate the impact of global coronal malalignment (GCMA) in surgically treated adult symptomatic lumbar deformity (ASLD) patients.

Methods: A multicentre retrospective analysis of a prospective ASD database.

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Objectives: To predict discharge destination after spinal cord injury (SCI) rehabilitation.

Study Design: A retrospective, single-center study. We collected the following data from medical charts: age, sex, living arrangement before injury, acute length of stay (LOS), level of injury on admission, American Spinal Injury Association Impairment Scale (AIS) on admission, Upper Extremity Motor Score (UEMS) on admission, Lower Extremity Motor Score on admission (LEMS), Spinal Cord Independence Measure (SCIM) scores on admission and discharge, and discharge destination.

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Objectives: To establish a machine learning model to predict functional outcomes after SCI with Spinal Cord Independence Measure (SCIM) using features present at the time of rehabilitation admission.

Study Design: A retrospective, single-center study. The following data were collected from the medical charts: age, sex, acute length of stay (LOS), level of injury, American Spinal Injury Association Impairment Scale (AIS), motor scores of each key muscle, Upper Extremity Motor Score (UEMS), Lower Extremity Motor Score (LEMS), SCIM total scores, and subtotal scores on admission and discharge.

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Article Synopsis
  • The study analyzed the effectiveness of a new asthma treatment combining fluticasone furoate, vilanterol, and umeclidinium, approved in Japan on February 18, 2021, by evaluating lung function in asthma patients.
  • Researchers conducted a before-after study with 114 asthma outpatients (mostly Japanese), finding significant improvements in lung function tests and asthma control after switching to the new treatment.
  • While 66% of subjects wanted to continue with the new treatment, mild local adverse effects were reported in 30% of patients, with no serious side effects observed, marking a promising advancement in asthma management.
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Background: Staphylococcus aureus is a global pathogen that is frequently responsible for healthcare-associated infections, including surgical site infections (SSIs). Current infection prevention and control approaches may be limited, with S. aureus antibiotic resistance remaining problematic.

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Article Synopsis
  • - The study analyzed 1512 patients aged 65 and older with cervical spine injuries, revealing that 6.3% of them had dementia, which was more common in older, mainly female patients with lower body mass index and higher frailty.
  • - Patients with dementia showed worse short-term outcomes, including lower functional ability in activities of daily living (ADLs) and a higher rate of dysphagia compared to those without dementia.
  • - Mortality rates were significantly higher in patients with dementia following their injuries, highlighting the adverse effects of dementia on recovery and survival in this demographic.
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Article Synopsis
  • - This multicenter retrospective study examines long-term outcomes for 169 patients (average age 67, mostly female) who underwent surgery for adult symptomatic lumbar deformity (ASLD) over an average follow-up period of 7.5 years.
  • - Results showed similar improvement in quality of life scores across different age groups (50s, 60s, 70s), but patients in their 70s experienced higher rates of reoperations (33%) and complications (65%).
  • - Overall, the study found favorable long-term surgical outcomes with a 23% reoperation rate and maintained spinal alignment, alongside a direct cost increase of 13% over the follow-up period.
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Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study.

J Orthop Sci

March 2024

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Article Synopsis
  • * Findings show that while patients who had early surgery had worse baseline neurological conditions, they experienced a greater improvement in motor scores within six months of surgery.
  • * Factors like delirium, pneumonia, and diabetes negatively affected recovery, suggesting that early surgery may be beneficial but requires more research for confirmation.
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This study is nationwide retrospective multi-center study to investigate the incidence and characteristics of blunt cerebrovascular injury (BCVI) in elderly Japanese patients with traumatic cervical spine injuries (CSI) including spinal cord injury (SCI) without major bone injury. The study enrolled 1512 patients (average age: 75.8 ± 6.

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For older patients with decreased reserve function, traumatic cervical spine injuries frequently lead to early mortality. However, the prognostic factors for early mortality remain unclear. This study included patients aged ≥65 years and hospitalized for treatment of traumatic cervical spine injuries in 78 hospitals between 2010 and 2020.

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Background: The oxidized high-density lipoprotein (oxHDL) is a possible marker for cardiovascular diseases. This study investigated the effects of smoking cessation with varenicline (a partial agonist of nicotinic acetylcholine receptors) on the levels of oxHDL in the serum of subjects compared with those of high-density lipoprotein cholesterol (HDL-C).

Methods: Data of 99 nicotine-dependent adult subjects who visited the smoking cessation outpatient services at International University of Health and Welfare Shioya Hospital were reviewed.

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Although traumatic cervical spine injuries in older adults are commonly caused by minor traumas, such as ground-level falls, their prognosis is often unfavorable. Studies examining the clinical characteristics of cervical spine injuries in older adults according to the external cause of injury are lacking. This study included 1512 patients of ≥ 65 years of age with traumatic cervical spine injuries registered in a Japanese nationwide multicenter database.

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Study Design: Retrospective multicenter study.

Objective: To compare the surgical outcomes and complications of posterior decompression between individuals with cervical spondylotic myelopathy (CSM) and those with ossification of the posterior longitudinal ligament (OPLL).

Setting: Seventeen medical institutions in Japan.

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Background: The Omicron variant of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) was identified in Japan in November 2021. This variant contains up to 36 mutations in the spike protein, the target of neutralizing antibodies, and can escape vaccine-induced immunity. A booster vaccination campaign began with healthcare workers and high-risk groups.

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Thumb carpometacarpal (CMC) joint instability is thought to be a debilitating disorder and, if left untreated, develops joint persistent synovitis and osteoarthritis. In this study, we report a novel surgical technique reconstructing the anterior oblique ligament, the dorsoradial ligament, and the intermetacarpal ligament simultaneously using both the transverse carpal ligament, and the palmaris longus tendon. Six patients with a mean age of 44 years showing no osteoarthritic changes by the radiographical examination underwent our anatomical three ligaments reconstruction for persistent painful thumb CMC joint instability.

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Does surgery improve neurological outcomes in older individuals with cervical spinal cord injury without bone injury? A multicenter study.

Spinal Cord

October 2022

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Study Design: Retrospective multicenter study.

Objectives: To investigate the neurological outcomes of older individuals treated with surgery versus conservative treatment for cervical spinal cord injury (CSCI) without bone injury.

Setting: Thirty-three medical institutions in Japan.

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Study Design: Retrospective Cohort Study.

Objective: The purpose of this study was to investigate the prognosis of respiratory function in elderly patients with cervical spinal cord injury (SCI) and to identify predictive factors.

Methods: We included 1353 cases of elderly cervical SCI patients collected from 78 institutions in Japan.

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Objective: This study aimed to examine the effects of galvanic vestibular stimulation (GVS) on visual vertical cognition and sitting balance in stroke patients.

Materials And Methods: Patients with unilateral supratentorial infarction and hemorrhagic lesions and healthy controls were recruited. Bipolar GVS was performed through the bilateral mastoid processes with an 1.

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Rib osteochondral graft for scaphoid proximal pole reconstruction.

J Plast Surg Hand Surg

March 2023

Department of Plastic and Reconstructive Surgery, Yokohama City University Hospital, Yokohama, Japan.

Background: An irreparable scaphoid proximal pole is challenging to treat because of the fragment size and limited blood supply. Salvage surgery, such as partial wrist fusion or proximal row carpectomy, may be performed but is not ideal for young patients. There are few reports of proximal scaphoid reconstruction using rib osteochondral grafts.

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