Changes in coagulation condition, cytokine, adhesion molecule after repair of type A aortic dissection.

Objective: Because residual dissection often exists even after the repair of a type A dissection, we evaluated coagulation conditions, cytokine levels, and adhesion molecule levels in mid-term follow up after repair of type A dissections.

Methods: Thrombin-antithrombin III complex (TAT), D-dimer, soluble interleukin-2 receptor (sIL-2R), soluble intercellular adhesion molecule (sICAM)-1, and type III procollagen peptide (PIIIP) were measured in 12 patients (mean age=63 years) following the repair of a type A aortic dissection at 6-82 months after repair (median=33 months).

Results: In the chronic phase, TAT and D-dimer were significantly higher in patients following the repair of a type A dissection compared to healthy controls (TAT; 12+/-8 vs.

[Changes in cytokines during perioperative period of hip arthroplasty in patients older than 80 years of age].

Background: Elevations of plasma inflammatory cytokines are related to the surgical intervention. We have examined the circulating interleukin 6, 8 (IL-6, IL-8) and CRP responses in patients older than 80 years during orthopedic hip arthroplasty.

Methods: After taking the signed informed consent, 8 patients were enrolled in this study.

Effects of nicardipine and diltiazem on fractal features of short-term heart rate variability--application of coarse graining spectral analysis.

Purpose: This study was designed to investigate the effects of nicardipine and diltiazem on the fractal features of short-term heart rate variability (HRV), using coarse graining spectral analysis (CGSA).

Methods: Eighteen healthy volunteers participated in this study; they were divided into two groups according to the drug administered. Five-minute electrocardiogram and arterial pressure recordings were made during stepwise infusions of either nicardipine (0.

Combined aortic valve replacement and coronary artery bypass grafting with in situ arterial grafts for porcelain aorta.

Patients with porcelain aorta carry a high risk of cerebral as well as systemic embolism during cardiac surgery. Here we describe a case of severe aortic stenosis and coronary artery disease combined with the circumferentially calcified aorta. The patient was a 77-year-old man who successfully received four coronary artery bypass grafts with in situ arterial grafts without clamping the aorta and aortic valve replacement.

Relationship between coagulation cascade, cytokine, adhesion molecule and aortic aneurysm.

Objectives: Patients with aortic aneurysm (AA) were in the chronic inflammatory condition and are often combined with disseminated intervascular coagulation. Recent studies demonstrated that atherosclerosis was inflammatory disease. AA and severe atherosclerosis with ulcer formation contain macrophages and T lymphocytes and accelerate the production of interleukin (IL)-2, which activates lymphocytes and lead to further adhesion of leukocytes.

Acutely dissected aorta: a reliable and leak-proof technique.

When repairing an acutely dissected aorta, a primary concern is bleeding from the anastomotic site. To prevent a hemorrhagic complication, a unique variation of wall reinforcement with xenopericardium together with GRF glue was introduced to provide a leakproof seal for ascending and descending aortic grafts.

Primary lymphoma of the central nervous system: a clinicopathologic study.

We performed clinicopathologic examinations of 27 cases of primary lymphoma of the central nervous system not related to acquired immune deficiency syndrome. We considered age and change of performance status (PS) to be especially important in clinical examination. We also conducted pathological studies of these tumors and the characteristics of their cells, in order to characterize pathological subtypes, cell kinetics, and involvement of viruses.

Recurrence of invasive cervical carcinoma more than 5 years after initial therapy.

Objective: To estimate the probability of and risk factors for the recurrence of invasive cervical carcinoma over 5 years after initial therapy.

Methods: Patients (n = 827) with invasive cervical carcinoma were treated and received follow-up care for up to 29 years. Late recurrence was defined as recurrence more than 5 years after initial therapy.