130 results match your criteria: "National Heart and Lung Institute. Imperial College London[Affiliation]"
For many years, clinical observations have suggested that there is an intrinsic connection between psychological state and skin diseases. Stress responses are typically mediated by several hormones, which are modulated the hypothalamic-pituitary-adrenal axis. This typical stress response is not only one theory for psychiatry disorder pathophysiology, but it also modifies hair growth by altering the skin's inflammatory environment.
View Article and Find Full Text PDFBackground Previous randomized control trials showed mixed results concerning the effect of omega-3 fatty acids (n-3 FAs) on atrial fibrillation (AF). The associations of n-3 FA blood levels with heart rhythm in patients with established AF are unknown. The goal of this study was to assess the associations of total and individual n-3 FA blood levels with AF type (paroxysmal versus nonparoxysmal), heart rate (HR), and HR variability in patients with AF.
View Article and Find Full Text PDFJ Am Heart Assoc
June 2023
Department of Cardiology, Royal Brompton and Harefield Hospitals Guy's and St Thomas' National Health Service Foundation Trust London UK.
Background No data currently exist comparing the contemporary iterations of balloon-expandable (BE) Edwards SAPIEN 3/Ultra and the self-expanding (SE) Medtronic Evolut PRO/R34 valves. The aim of the study was the comparison of these transcatheter heart valves with emphasis on patients with small aortic annulus. Methods and Results In this retrospective registry, periprocedural outcomes and midterm all-cause mortality were analyzed.
View Article and Find Full Text PDFBackground Observational studies suggest that reproductive factors are associated with cardiovascular disease, but these are liable to influence by residual confounding. This study explores the causal relevance of reproductive factors on cardiovascular disease in women using Mendelian randomization. Methods and Results Uncorrelated (<0.
View Article and Find Full Text PDFEffects of continuous positive airway pressure (CPAP) on right ventricular (RV) function in patients with untreated mild-to-moderate obstructive sleep apnea (OSA) are unclear. In this exploratory analysis of cardiac magnetic resonance (CMR)-derived indices of RV function in patients with minimally symptomatic OSA from the MOSAIC randomized control trial we found no effect of CPAP on RV CMR parameters. In those with lower RV ejection fraction and higher RV end-diastolic volume (EDV) at baseline, CPAP treatment appeared to improve RV function with a significant reduction in both RV EDV and RV end-systolic volume although between-group effects were not observed.
View Article and Find Full Text PDFAm J Respir Crit Care Med
February 2023
National Heart and Lung Institute Imperial College London London, United Kingdom.
Am J Respir Crit Care Med
March 2023
National Heart and Lung Institute Imperial College London, United Kingdom.
Am J Respir Crit Care Med
March 2023
Royal Brompton and Harefield Hospitals Guy's and St. Thomas' NHS Foundation Trust London, United Kingdom.
Clin Transl Allergy
September 2022
Am J Respir Crit Care Med
November 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Am J Respir Crit Care Med
November 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Am J Respir Crit Care Med
November 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Background: The past decade has seen a substantial rise in the employment of modern data-driven methods to study atopic dermatitis (AD)/eczema. The objective of this study is to summarise the past and future of data-driven AD research, and identify areas in the field that would benefit from the application of these methods.
Methods: We retrieved the publications that applied multivariate statistics (MS), artificial intelligence (AI, including machine learning-ML), and Bayesian statistics (BS) to AD and eczema research from the SCOPUS database over the last 50 years.
Am J Respir Crit Care Med
September 2022
Royal Brompton Hospital London, United Kingdom.
Am J Respir Cell Mol Biol
July 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Am J Respir Crit Care Med
June 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Am J Respir Crit Care Med
February 2022
Lung Health Center and Division of Pulmonary, Allergy and Critical Care Medicine University of Alabama at Birmingham Birmingham, Alabama.
Am J Respir Crit Care Med
February 2022
National Heart and Lung Institute Imperial College London London, United Kingdom.
Eur Respir J
November 2021
Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Am J Respir Crit Care Med
November 2021
Keck School of Medicine University of Southern California, Los Angeles Los Angeles, California.
Although Thoracic Endovascular Aortic Repair is usually applied to patients without connective tissue disorders, our case shows its potential for complicated type B aortic dissection in a Marfan patient as a feasible alternative to open redo surgery with good short-term outcomes.
View Article and Find Full Text PDFAm J Respir Crit Care Med
October 2021
Royal Brompton & Harefield Hospitals London, United Kingdom.