[Ovarian cancer].

Primary aggressive cyto-reduction followed by adjuvant chemotherapy has so far been the standard treatment modality for advanced ovarian cancer. However, as cisplatin-containing regimens have been shown to generate high efficacy rates, a new modality involving extirpation of the tumor after chemotherapy, rather than surgery as the first treatment, has become available for patients with stage III or IV ovarian cancer in whom tumor cells may remain after surgery. In our examination of 56 cases, higher efficacy rates, higher tumor-debulking rates, lower frequency of extended surgery and longer median survival time were obtained with preoperative chemotherapy in comparison with postoperative chemotherapy.

Development of the pharynx in normal and malformed fetuses.

We studied the development of the pharynx in human embryos and fetuses. Embryos and fetuses from 4.5 mm crown-rump length (CRL) to 40 mm CRL were processed for microscopic examination.