The 'roller coaster effect' in premolar extraction cases: clear aligners vs. straight-wire appliance.

Objectives: This study aimed to quantitatively investigate the intractable 'roller coaster effect' (RCE) that occurs in premolar extraction cases treated with clear aligner therapy (CAT) or straight-wire appliance (SWA).

Methods: Protrusion cases treated with extraction of bilateral first premolars were included. Pre- and post-treatment cephalograms were obtained to measure the bending angle of occlusal plane (BAOP), namely the occlusal intersection angle between the anterior occlusal plane (AOP) and posterior occlusal plane (POP).

Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling.

Background: Hybrid closed-loop systems are a new class of technology to manage type 1 diabetes mellitus. The system includes a combination of real-time continuous glucose monitoring from a continuous glucose monitoring device and a control algorithm to direct insulin delivery through an insulin pump. Evidence suggests that such technologies have the potential to improve the lives of people with type 1 diabetes mellitus and their families.

COVID-19-Related Knowledge, Fear, and Infection Control of Dental Staff.

Objective: This study aimed to investigate the correlations between knowledge, fear, infection control practices, and attitude of dental staff in Korea.

Methods: This study was conducted to investigate the correlation between COVID-19-related knowledge, fear, and infection control attitudes and practices.

Results: COVID-19-related knowledge was significantly correlated with infection control attitudes and practices (r = 0.

Association Between Sealant and Early Impairment of First Molars in 6-14-Year-Olds: A 9-Year Follow-Up Using South Korean Cohort Data.

Objectives: This study aimed to analyse the 2010-2018 cohort data of the National Health Insurance Service to examine the association between applying sealants in the first molars of children and their early dental impairment.

Methods: Based on the two-level mixed effect model (individual four teeth), the study participants were divided into two groups: those with sealants on all four first molars and those without sealants to determine the association between sealants and early impairment. We analysed teeth that had undergone extraction or canal filling to determine early impairment.

Addressing oral cancer inequalities: a multifaceted approach to equitable healthcare.

Oral cancer remains a persistent health challenge globally, with rising incidence and flat survival rates, particularly among disadvantaged populations. This paper explores the socioeconomic, ethnic and cultural factors contributing to inequalities in oral cancer care, such as limited access to healthcare, lower education levels, financial constraints and systemic disadvantages based on ethnicity and cultural practices. Addressing these inequalities requires a multi-faceted approach, including community outreach, patient education and policy advocacy.

Bacterial biofilm-based bioleaching: Sustainable mitigation and potential management of e-waste pollution.

Significant advances in the electrical and electronic industries have increased the use of electrical and electronic equipment and its environmental emissions. The e-waste landfill disposal has deleterious consequences on human health and environmental sustainability, either directly or indirectly. E-waste containing ferrous and non-ferrous materials can harm the surrounding aquatic and terrestrial environments.

Rapid assessment of noma: Reporting on forgotten and neglected disease in Ethiopia.

Background: Noma is a rapidly progressing, invasive, and debilitating orofacial disease that primarily affects the most vulnerable and marginalised populations worldwide. The highest- risk group includes pre-school children, exposed to other risk factors, such as malnutrition and poverty-related diseases. Since 2010, Ethiopia has reported an increasing number of noma cases, primarily identified through medical missions.

Exploring the therapeutic potential of extract: molecular docking, dynamics, and ADMET properties for cancer treatment and anti-inflammatory activity.

Colorectal cancer remains a global health challenge, prompting the exploration of natural compounds for treatment. shows promise as a source of activity biomolecules. This study analyzed the dynamics, molecular docking and ADMET properties of the extract, highlighting interaction with inflammatory protein.

Association of Marijuana Use With Psychological Distress Among Adults in United States.

Purpose: Determine the association of marijuana use with serious psychological distress (SPD) among adults aged 18 years or older using a large, nationally representative sample of US households.

Design: Cross-sectional analysis.

Setting: Data from the National Survey on Drug Use and Health, 2021.

From teeth to ethnicity: A neural network approach to predicting population of origin through dental traits and anomalies.

Background: This study aimed to investigate the prevalence of dental traits and anomalies in five North Indian populations (Khas Bodhi, Jaat, Khatri, Garhwali, and Gujjar) and predict the population of origin based on these traits and anomalies for forensic applications.

Methods: We assessed dental traits and anomalies in 454 individuals through intraoral examination. Neural network analysis was employed to predict the population of origin based on a combination of dental traits and anomalies.

ArtiSential laparoscopic cholecystectomy: a comparative analysis with robotic single-port cholecystectomy.

Purpose: Laparoscopic cholecystectomy is the gold standard procedure for benign gallbladder disease. However, reducing ports still causes frustration when using various instruments. We investigated early perioperative outcomes of laparoscopic single site + 1 cholecystectomy using ArtiSential instruments (ArtiSential laparoscopic cholecystectomy [ALC], LIVSMED).

ZygoPlanner: A three-stage graphics-based framework for optimal preoperative planning of zygomatic implant placement.

Zygomatic implant surgery is an essential treatment option of oral rehabilitation for patients with severe maxillary defect, and preoperative planning is an important approach to enhance the surgical outcomes. However, the current planning still heavily relies on manual interventions, which is labor-intensive, experience-dependent, and poorly reproducible. Therefore, we propose ZygoPlanner, a pioneering efficient preoperative planning framework for zygomatic implantation, which may be the first solution that seamlessly involves the positioning of zygomatic bones, the generation of alternative paths, and the computation of optimal implantation paths.

SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.

Saliva contains antimicrobial peptides considered integral components of host innate immunity, and crucial for protection against colonizing microbial species. Most notable is histatin-5 which is exclusively produced in salivary glands with uniquely potent antifungal activity against the opportunistic pathogen Candida albicans. Recently, SARS-CoV-2 was shown to replicate in salivary gland acinar cells eliciting local immune cell activation.

Mobility Medicine: A call to unify hyper-fragmented specialties by abstracts sent to 2025Pdm3, and typescripts to Ejtm3, and .

Mega scientific conferences increasingly suffer from the need for short and poster presentations without discussion. An alternative is to organize workshops in hotels large enough to accommodate all participants. This significantly increases the opportunities for constructive discussion during breakfasts, lunches, dinners and long evenings that can bring together experts of scientific and clinical sub-specialties and young fellows.

Porphyromonas gingivalis-Lipopolysaccharide Induced Gingival Fibroblasts Trained Immunity Sustains Inflammation in Periodontitis.

Aim: To investigate whether trained immunity occurs in gingival fibroblasts (GFs) and its relationship to the persistence of inflammation in periodontitis.

Methods: Periodontally healthy and inflammatory gingival fibroblasts (HGFs and IGFs) were cultured through continuous adherence subculture of tissue blocks. Trained immunity in HGFs was evaluated via a classic in vitro model, with relevant markers assessed via enzyme-linked immunosorbent assay, lactate content assay, glycolytic rate assay, and chromatin immunoprecipitation.

Approach to determining etiology of hypophosphatemia in a patient with coexisting phosphaturic mesenchymal tumor and fibrous dysplasia.

Dysregulated FGF23 production is a demonstrated cause of hypophosphatemia and osteomalacia. Diseases associated with these conditions include phosphaturic mesenchymal tumor (PMT) causing tumor induced osteomalacia, various forms of rickets, and fibrous dysplasia (FD). Coexistence of 2 conditions that can increase FGF23 concentrations is rare.

Clinical and Radiographic Efficacy of Low-level Laser Therapy and Formocresol as Pulpotomy Agents in Primary Molars: A Systematic Review and Meta-analysis.

Research Question: To evaluate the effectiveness of low-level laser therapy (LLLT) as a pulpotomy agent in primary molars.

Research Protocol: This systematic review followed the recommendation of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline 2020.

Literature Search: An electronic search of the databases was performed to find the effectiveness of LLLT over formocresol as a pulpotomy agent in primary molars in children aged between 3 and 10 years.

The impact of psychological well-being on academic performance among undergraduate dental students.

Objective: To assess the relationship between psychological wellbeing and academic performance among undergraduate dental students.

Methods: The analytical, cross-sectional study was done at a dental college in Rawalpindi, Pakistan, from January to July 2023, and comprised dental students after getting approval from Ethical Review Committee. Data on psychological wellbeing was collected using a short version of the Psychological Wellbeing Scale, assessing autonomy, environmental mastery, personal growth, positive relations with others, purpose in life, and selfacceptance.

Exploring the adoption and utilisation of ChatGPT in everyday academic practices among medical and dental students of Rawalpindi and Islamabad: a study on the impact and perceived effectiveness.

Objectives: To assess the usage of chatbot generative pretrained transformer among medical and dental students in Pakistan.

Methods: The cross-sectional study was conducted at the Army Medical College, National University of Medical Sciences, Islamabad, Pakistan, from June 15 to July 31, 2023, and comprised medical and dental students in public and private medical and dental colleges of Rawalpindi and Islamabad who had used the chatbot generative pretrained transformer programme at least once for their academics or had prior knowledge of it. Responses were obtained through a structured online survey.

Evaluation of satisfaction level of Sehat Sahulat Programme among patients and doctors in Lahore and Gujranwala districts, Pakistan.

Objective: To evaluate the satisfaction level of patients and doctors with a health insurance scheme in two districts of Punjab province.

Methods: The analytical, cross-sectional study was conducted from June 2022 to November 2022 at Farooq Hospital West Wood Branch, Akhtar Saeed Trust Hospital, Lahore, Pakistan, and the District Headquarter Hospital, Gujranwala, Pakistan. The sample included doctors and adult inpatients receiving treatment under the Sehat Sahulat Programme.

Correlations Between Dental Hygiene Students' Participation in Program Assessments and Program Improvements.

Students can play an influential role in the assessment process of dental hygiene programs; however, little is known about how students contribute to program improvements. The purpose of this study was to explore the correlations between dental hygiene students' participation in program assessments and program improvements. The adapted National Institute Learning Outcomes Assessment questionnaire survey was distributed via email to 325 dental hygiene program administrators in the United States identified from the Commission on Dental Accreditation database.

Assessment of Stress Distribution Around Traditional and Sleeve Fixed Partial Denture Designs: Finite Element Analysis.

Objectives:  The aim of this research is to evaluate/compare the use of traditional versus sleeve fixed partial denture (PD) designs made from different materials on supporting structures. The comparison included three- and four-unit PD cases.

Materials And Methods:  Four finite element models are used in the research.