25 results match your criteria: "National Clinical Research Center for Orthopaedics[Affiliation]"

[Total knee replacement for bilateral knee osteoarthritis combined with congenital patella dislocation:a case report].

Zhongguo Gu Shang

October 2024

Senior Department of Orthopaedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China; National Clinical Research Center for Orthopaedics and Sports Rehabilitation, Beijing 100853, China; Department of Orthopaedics, the Eighth Medical Center of Chinese PLA General Hospital, Beijing 100091, China.

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[The reconstruction techniques and mid-term clinical outcomes of hip revision for acetabular bone defect after total hip arthroplasty].

Zhonghua Wai Ke Za Zhi

September 2024

Senior Department of Orthopaedics, the Forth Medical Center of Chinese People's Liberation Army General Hospital, National Clinical Research Center for Orthopaedics, Sports Medicine and Rehabilitation, Beijing 100048, China.

Article Synopsis
  • The study analyzes three different reconstruction methods for hip revision surgeries in patients with acetabular bone defects following total hip arthroplasty (THA), focusing on mid-term clinical outcomes.
  • It involves a total of 109 patients categorized into three groups based on the surgical technique used: normal cup, augment, and triflange, with varying patient demographics and methods.
  • Clinical and radiographic evaluations were conducted over time, measuring factors like leg length discrepancy and hip function, with comparisons made before and after surgery to assess effectiveness.
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Objective: To investigate the effectiveness of HoloSight Orthopaedic Trauma Surgery Robot-assisted infra-acetabular screw placement for treatment of acetabular fractures.

Methods: The clinical data of 23 patients with acetabular fractures treated with open reduction and internal fixation and infra-acetabular screw placement in two medical centers between June 2022 and October 2023 were retrospectively analyzed. According to the the method of infra-acetabular screw placement, the patients were divided into navigation group (10 cases, using HoloSight Orthopaedic Trauma Surgery Robot-assisted screw placement) and freehand group (13 cases, using traditional X-ray fluoroscopy to guide screw placement).

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Article Synopsis
  • Wound healing is a big medical problem that scientists are trying to solve.
  • They found out that tiny bubbles called extracellular vesicles (EVs) from 3D cell cultures can help heal wounds better.
  • In their study, they discovered that these EVs boost a protein called ANXA1, which helps certain immune cells change and promotes faster wound healing in animals.
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[Early effectiveness of computer navigation system-assisted transiliac-transsacral screws placement for posterior pelvic ring injuries].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi

September 2023

Department of Orthopaedic Trauma, the Fourth Medical Center, Chinese PLA General Hospital, Beijing, 100048, P. R. China.

Objective: To investigate the early effectiveness of transiliac-transsacral screws internal fixation assisted by augmented reality navigation system HoloSight (hereinafter referred to as "computer navigation system") in the treatment of posterior pelvic ring injuries.

Methods: A retrospective analysis was made in the 41 patients with posterior pelvic ring injuries who had been treated surgically with transiliac-transsacral screws between June 2022 and June 2023. The patients were divided into navigation group (18 cases, using computer navigation system to assist screw implantation) and freehand group (23 cases, using C-arm X-ray fluoroscopy to guide screw implantation) according to the different methods of transiliac-transsacral screws placement.

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[Current situation and development of perforator flap].

Zhongguo Gu Shang

August 2023

Senior Department of Orthopaedics, PLA General Hospital, The National Clinical Research Center for Orthopaedics, Sports Medicine & Rehabilitation, Beijing 100048, China.

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Article Synopsis
  • This study evaluated the effectiveness of uniplanar pedicle screws (UPPS) in internal fixation for thoracolumbar fractures using biomechanical testing on 24 cadaveric spine specimens.
  • Two configurations, the 6-screw and 4-screw/2-NIS, were tested with different types of pedicle screws (FAPS, UPPS, PAPS) under various loads.
  • The results showed that UPPS provided better stability compared to PAPS and combined the advantages of both FAPS and PAPS, making it a suitable option for minimally invasive treatments of thoracolumbar fractures.
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Objective: To compare the reduction qualities of three-dimensional visible technique without fluoroscopy and two-dimensional fluoroscopy for unstable pelvic fractures during operations.

Methods: The clinical data of 40 patients with unstable pelvic fractures, who met the selection criteria in three clinical centers between June 2021 and September 2022, were retrospectively analyzed. According to the reduction methods, the patients were divided into two groups.

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Objective: Periprosthetic fracture in total hip arthroplasty (THA) can be catastrophic, and early detection and appropriate management are vital to the overall prognosis. This study aimed to describe and summarize the features of undetected intraoperative periprosthetic femoral fractures (IPFFs) in primary THA patients and treatment measures and to review the relevant literature.

Methods: We reviewed a total of 6350 primary THAs performed at our institution between January 2013 and December 2020 and screened all IPFFs.

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Purpose: Schenck IV knee dislocation patients have dissatisfactory knee function and return-to-sport rate with the existing treatment methods. The purpose of this study was to illustrate a one-stage arthroscopic multiple ligament reconstruction method for treating Schenck IV knee dislocations.

Methods: A retrospective case series study was performed.

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Objectives: While many studies have presented excellent short-term outcomes of the metaphyseal sleeves used in revision total knee arthroplasty (TKA), currently published mid-term results remain limited and some controversial issues remain unresolved. The purpose of this study was to investigate clinical and radiographic mid-term outcomes of the sleeves for the management of metaphyseal bone defects in revision TKAs.

Methods: From 2015 to 2019, 44 patients (45 knees) who were operated with cementless porous-coated metaphyseal sleeve in revision TKA were included in this study.

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Aim: Subtrochanteric shortening osteotomy (SSO) is often applied during total hip arthroplasty (THA) in high hip dislocations. The aim of the present paper was to evaluate the results of fixation by autogenous cortical plate technique on sites of SSO in THA for patients with Crowe type IV developmental dysplasia of the hip (DDH).

Methods: We conducted a historical prospective cohort study and reviewed 67 patients (82 THAs) with SSO performed between March 2016 and May 2020.

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Prosthetic joint infection (PJI) is often considered as one of the most common but catastrophic complications after artificial joint replacement, which can lead to surgical failure, revision, amputation and even death. It has become a worldwide problem and brings great challenges to public health systems. A small amount of microbe attaches to the graft and forms a biofilm on its surface, which lead to the PJI.

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Rheumatoid Arthritis is a universal disease that severely affects the normal function of human joints and the quality of life. Millions of people around the world are diagnosed with rheumatoid arthritis every year, carrying a substantial burden for both the individual and society. Hydrogel is a polymer material with good mechanical properties and biocompatibility, which shows great potential in the treatment of rheumatoid arthritis.

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Human joints move thousands of times a day. The articular cartilage plays a vital role in joints' protection. If there is dysfunction in cartilage lubrication, cartilage cannot maintain its normal function.

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Objective: The mechanical high modulus structure of the proximal femur could guide clinical surgical treatment and instrument design of proximal femoral fractures. The purpose of this study is to analyze and verify the mechanical structure of the proximal femur.

Methods: A total of 375 patients with intertrochanteric fractures were imaged using computed tomography (CT) scans.

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To compare the biomechanical stability of slide compression anatomic plates of the femoral neck, cannulated compression screws and dynamic hip screws with derotation screws for stabilizing unstable femoral neck fractures (Pauwels angle = 70°). Pauwels III femoral neck fractures were created on 45 Sawbones femurs and randomly assigned to three implant groups (1:1:1). The biomechanical stability of all Sawbones in each treatment group was evaluated with three tests.

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Background: Osteochondral lesion of the talus (OLT) is one of the most common ankle injuries, which will lead to biomechanical changes in the ankle joint and ultimately affect ankle function. Finite element analysis (FEA) is used to clarify the effect of talus osteochondral defects on the stability of the ankle joint at different depths. However, no research has been conducted on talus osteochondral defect areas that require prompt intervention.

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Article Synopsis
  • This study aimed to compare the inflammatory markers and radiographic outcomes of traditional manual total knee arthroplasty (CM-TKA) versus MAKO-robotic assisted total knee arthroplasty (MA-TKA) in patients with knee osteoarthritis.
  • Researchers analyzed 65 patients who had unilateral TKA, focusing on blood loss, knee function, inflammatory indicators, and radiographic results post-surgery.
  • Results showed that the MA-TKA group had significantly less estimated blood loss and lower inflammatory markers shortly after surgery, along with better alignment outcomes in radiographic evaluations compared to the CM-TKA group.
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Closed reduction and internal fixation with three cannulated compression screws is a common method for treating femoral neck fractures in young and middle-aged patients. Protocols including the inverted triangle configuration and dispersion of the screws still needed further supports. The purpose of this study was to explore a novel oblique triangle configuration (OTC) of three screws in fixing femoral neck fractures based on the morphology of the femoral neck isthmus (FNI).

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Falls prevention in China: time for action.

Lancet Public Health

December 2021

China Center for Health Development Studies, Peking University, Beijing, China.

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Background: The cross-sectional area of three parallel screws might affect the stability of the internal fixation of femoral neck fractures. The screws fixed in the oblique-triangle configuration (OTC) were assumed to have a larger cross-sectional area, but the biomechanical stability has not yet been validated. In this study, finite element analyses were performed to compare the biomechanical properties of the internal fixation fixed by the OTC and the traditional Inverted Equilateral Triangle Configuration (IETC).

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Emerging evidence suggests that the shift between osteogenic and adipogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) determines bone mass. Our study was aimed at testing whether a long noncoding RNA called zinc finger antisense 1 (ZFAS1) participates in the differentiation commitment of BMSCs during osteoporosis. We found that ZFAS1 expression was downregulated during osteogenic differentiation and upregulated during adipogenic differentiation.

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Purpose: A hybrid pedicle screw system for minimally invasive spinal fixation was developed based on the uniplanar pedicle screw construct and a new intermediate screw. Its biomechanical performance was evaluated using finite element (FE) analysis.

Methods: A T12-L2 FE model was established to simulate the L1 vertebral compression fracture with Magerl classification A1.

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