5 results match your criteria: "National Clinical Research Center for Health[Affiliation]"

Anatomical and immunohistochemical analyses of the fusion of the premaxillary-maxillary suture in human fetuses.

J Orofac Orthop

March 2024

Department of Pathology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Health, 310052, Hangzhou, China.

Purpose: The development of the premaxillary-maxillary suture (PMS) in human fetuses and a possible association between the fusion time of the PMS and maxillary deficiency were investigated. Expression of transforming growth factor beta (TGF-β1 and TGF-β3) and of fibulins (fibulin‑1 and fibulin-5) were also investigated.

Methods: We analyzed 36 human fetus cadavers (19 males, 17 females; average age 23.

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Background: Despite having an overall benign course, non-traumatic non-aneurysmal subarachnoid hemorrhage (naSAH) is still accompanied by a risk of clinical complications and poor outcomes. Risk factors and mechanisms of complications and poor outcomes after naSAH remain unknown. Our aim was to explore the effect of stress-induced hyperglycemia (SIH) on complication rates and functional outcomes in naSAH patients.

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To test the gene sequence of 3 patients with Waardenburg syndrome(WS) using the next generation sequencing technology in order to explore the possible mechanism of molecular genetics. Medical histories of the family members were collected. Physical examination, audiological evaluation and CT examination were performed.

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Sensory recovery and oral health-related quality of life following tongue reconstruction using non-innervated radial forearm free flaps.

Oral Oncol

October 2021

Orofacial Pain & TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, 136 Hanzhong Road, Nanjing 210029, China; Section for Orofacial Pain and Jaw Function, School of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Center for Sensory-Motor Interaction (SMI) Aalborg University, Aalborg, Denmark.

Objectives: This study aimed to monitor the recovery of somatosensory function and oral health-related quality of life after tongue reconstruction using a non-innervated radial forearm free flap (RFFF).

Methods: Twenty patients (9 men, age: 42-67 years) underwent tongue reconstruction with non-innervated RFFFs, and twenty age- and sex-matched controls were included in this study. Quantitative sensory testing (QST), including cold, warm, and mechanical detection thresholds (CDT, WDT, MDT); cold, heat, and mechanical pain thresholds (CPT, HPT, MPT); and static two-point, sharp/blunt, and direction discrimination (S2-PD, S/BD, DD) were determined 9 months and 18 months after surgery on the surgical (9 M, 18 M) and contralateral sides (9Mc, 18Mc).

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A study on facial features of children with Williams syndrome in China based on three-dimensional anthropometric measurement technology.

Am J Med Genet A

September 2020

Department of Pediatric Health Care, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Health, Zhejiang, Hangzhou, China.

To describe special facial features of children with Williams syndrome in China by using method of three-dimensional craniofacial anthropometry. Using three-dimensional stereo photogrammetric device, 14 craniofacial anthropometric measurements were performed and five indices were calculated in 52 children with Williams syndrome and 208 age and sex matched controls of Han Chinese ethnicity. Except intercanthal width, mouth breadth, morphological face height, nasal height-breadth index, nasal breadth-depth index, morphological ear index, the Williams syndrome group under 3 years old were smaller than the control group in the other 12 variables.

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