405 results match your criteria: "National Centre for Scientific Research NCSR "Demokritos"[Affiliation]"

The burial of metals in hoards is a trademark phenomenon of prehistoric Europe that may be counterintuitive to perceptions of value nowadays. For the first time here, we establish detailed biographies of a large corpus of hoarded metal objects, providing new insights into how societies in the second millennium BC engaged with their convertible material wealth. We move beyond previous research on prehistoric hoarding commonly focussing on separate questions such as what was placed in hoards, who selected the objects, what were the origins of materials, and where and when they were buried.

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  • * The measurements utilized both semileptonic and hadronic decays of top quarks, along with events focused on single top quark production in the electroweak t channel.
  • * The combined result for the top quark mass is 172.52 GeV, with a reduced total uncertainty of 0.33 GeV, showcasing an improvement of 31% over previous measurements.
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A search is presented for baryon number violating interactions in top quark production and decay. The analysis uses data from proton-proton collisions at a center-of-mass energy of 13 TeV, collected with the CMS detector at the LHC with an integrated luminosity of 138  fb^{-1}. Candidate events are selected by requiring two oppositely charged leptons (electrons or muons) and exactly one jet identified as originating from a bottom quark.

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Background: Hypertension worsens outcomes in SARS-CoV-2 patients. Sartans, a type of antihypertensive angiotensin receptor blocker-(ARB), reduce COVID-19 morbidity and mortality by targeting angiotensin-converting enzyme-2 (ACE2). This study aimed to evaluate the antiviral and antihypertensive effects of nirmatrelvir, commercial sartans (candesartan, losartan, and losartan carboxylic (Exp3174)), and newly synthesized sartans (benzimidazole-N-biphenyl carboxyl (ACC519C) and benzimidazole-N-biphenyl tetrazole (ACC519T)), compared to nirmatrelvir, the antiviral component of Paxlovid.

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Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system.

Cell Rep

June 2024

Department of Medical Genetics, Box 238, Level 6, Addenbrooke's Treatment Centre, Cambridge Biomedical Research Campus, Cambridge CB2 0QQ, UK; Early Cancer Institute, Department of Oncology, Box 197, Hutchison Research Centre, Cambridge Biomedical Research Campus, Cambridge CB2 0XZ, UK. Electronic address:

Xeroderma pigmentosum (XP) is caused by defective nucleotide excision repair of DNA damage. This results in hypersensitivity to ultraviolet light and increased skin cancer risk, as sunlight-induced photoproducts remain unrepaired. However, many XP patients also display early-onset neurodegeneration, which leads to premature death.

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A search for exotic decays of the Higgs boson () with a mass of 125 to a pair of light pseudoscalars is performed in final states where one pseudoscalar decays to two quarks and the other to a pair of muons or leptons. A data sample of proton-proton collisions at corresponding to an integrated luminosity of 138 recorded with the CMS detector is analyzed. No statistically significant excess is observed over the standard model backgrounds.

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Volatile Profiling of Spirulina Food Supplements.

Foods

April 2024

Institute of Nanoscience and Nanotechnology, National Center for Scientific Research "Demokritos", Patriarchou Grigoriou E & 27 Neapoleos Str., Agia Paraskevi, 15341 Athens, Greece.

Spirulina, a cyanobacterium widely used as a food supplement due to its high nutrient value, contains volatile organic compounds (VOCs). It is crucial to assess the presence of VOCs in commercial spirulina products, as they could influence sensory quality, various processes, and technological aspects. In this study, the volatile profiles of seventeen commercial spirulina food supplements were determined using headspace solid-phase microextraction (HS-SPME), coupled with gas chromatography-mass spectrometry (GC-MS).

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  • Scientists found a new type of genetic change called t(X;21) in some patients with blood diseases like myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
  • This change happened along with other mutations in certain genes, but it didn't create new fusion genes as might be expected.
  • They discovered that this genetic change is linked to the loss of two important genes (BCOR and RUNX1), which affects how cells behave in these diseases.
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The observation of WWγ production in proton-proton collisions at a center-of-mass energy of 13 TeV with an integrated luminosity of 138  fb^{-1} is presented. The observed (expected) significance is 5.6 (5.

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A search is reported for near-threshold structures in the J/ψJ/ψ invariant mass spectrum produced in proton-proton collisions at sqrt[s]=13  TeV from data collected by the CMS experiment, corresponding to an integrated luminosity of 135  fb^{-1}. Three structures are found, and a model with quantum interference among these structures provides a good description of the data. A new structure is observed with a local significance above 5 standard deviations at a mass of 6638_{-38}^{+43}(stat)_{-31}^{+16}(syst)  MeV.

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Ultrafine particles (UFP, those with diameters ≤ 100 nm), have been reported to potentially penetrate deeply into the respiratory system, translocate through the alveoli, and affect various organs, potentially correlating with increased mortality. The aim of this study is to assess long-term trends (5-11 years) in mostly urban UFP concentrations based on measurements of particle number size distributions (PNSD). Additionally, concentrations of other pollutants and meteorological variables were evaluated to support the interpretations.

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  • This study focuses on how to accurately measure equivalent black carbon (eBC) concentrations using filter absorption photometers (FAPs) by understanding the mass absorption cross-section (MAC).
  • Researchers analyzed data from 22 different sites to compare various methods for calculating MAC, leading to different classifications of eBC such as LeBC, MeBC, and ReBC, with significant differences observed in measurement outcomes.
  • Results showed that MAC varies by site and season, influencing the observed trends in elemental carbon (EC), revealing a need for careful MAC consideration when interpreting eBC data to reduce uncertainty in measurements.
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This work presents the synthesis of N-doped nanoporous carbon materials using the Ionic Liquid (IL) 1-butyl-3-methylimidazolium tricyanomethanide [BMIM][TCM] as a fluidic carbon precursor, employing two carbonization pathways: templated precursor and pyrolysis/activation. Operando monitoring of mass loss during pyrolytic and activation treatments provides insights into chemical processes, including IL decomposition, polycondensation reactions and pore formation. Comparatively low mass reduction rates were observed at all stages.

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  • The 'QuantitatEVs' workshop focused on quantitative methods for analyzing extracellular vesicles (EVs), from large bulk samples to individual vesicles, emphasizing new technologies.
  • * The event explored critical issues in analyzing EV-associated molecules and biophysical features, which are key for discovering and validating EV biomarkers for clinical use.
  • * Held in Trento, Italy, from January 31 to February 2, 2023, the workshop included a follow-up event in Milan aimed at supporting early career researchers.
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The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated luminosity of 138  fb^{-1}. The reconstructed final state consists of a jet, significant missing transverse momentum, and a τ lepton reconstructed through its hadronic or leptonic decays.

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A search for dark matter in events with a displaced nonresonant muon pair and missing transverse momentum is presented. The analysis is performed using an integrated luminosity of 138  fb^{-1} of proton-proton (pp) collision data at a center-of-mass energy of 13 TeV produced by the LHC in 2016-2018. No significant excess over the predicted backgrounds is observed.

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The first evidence for the Higgs boson decay to a Z boson and a photon is presented, with a statistical significance of 3.4 standard deviations. The result is derived from a combined analysis of the searches performed by the ATLAS and CMS Collaborations with proton-proton collision datasets collected at the CERN Large Hadron Collider (LHC) from 2015 to 2018.

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The coordination chemistry of 2-pyridyl ketoximes continues to attract the interest of many inorganic chemistry groups around the world for a variety of reasons. Cadmium(II) complexes of such ligands have provided models of solvent extraction of this toxic metal ion from aqueous environments using 2-pyridyl ketoxime extractants. Di-2-pyridyl ketone oxime (dpkoxH) is a unique member of this family of ligands because its substituent on the oxime carbon bears another potential donor site, i.

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Glucocorticoid stress hormones stimulate vesicle-free Tau secretion and spreading in the brain.

Cell Death Dis

January 2024

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.

Chronic stress and elevated levels of glucocorticoids (GCs), the main stress hormones, accelerate Alzheimer's disease (AD) onset and progression. A major driver of AD progression is the spreading of pathogenic Tau protein between brain regions, precipitated by neuronal Tau secretion. While stress and high GC levels are known to induce intraneuronal Tau pathology (i.

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  • - The study investigates the strange quark content of protons by measuring the production cross section of W bosons and charm quarks in proton-proton collisions at 13 TeV, using data from the CMS detector at the LHC.
  • - W bosons are identified through their decays into leptons (electrons or muons) and neutrinos, while charm quarks are tagged by detecting muons or secondary vertices in jets.
  • - The measurements, which reach a precision of 1%, include both inclusive and differential analyses based on the transverse momentum and pseudorapidity of the leptons, and the results are compared with advanced theoretical predictions in quantum chromodynamics.
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The measurement of Z boson production is presented as a method to determine the integrated luminosity of CMS data sets. The analysis uses proton-proton collision data, recorded by the CMS experiment at the CERN LHC in 2017 at a center-of-mass energy of 13. Events with Z bosons decaying into a pair of muons are selected.

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Quasireal photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The coherent J/ψ photoproduction cross section in ultraperipheral lead-lead collisions is measured as a function of photon-nucleus center-of-mass energies per nucleon (W_{γN}^{Pb}) over a wide range of 40 View Article and Find Full Text PDF

The goal of this study is to provide a benchmark for the use of Monte Carlo simulation when applied to coincidence summing corrections. The examples are based on simple geometries: two types of germanium detectors and four kinds of sources, to mimic eight typical measurement conditions. The coincidence corrective factors are computed for four radionuclides.

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Several cross-section measurements of neutron-induced reactions on Ge found in literature, are performed utilizing Ge targets. The production of the same residual nucleus as the measured one might occur as a result of the unavoidable presence of neighboring isotopes in the same target, acting as a contamination. Corrections must be made based on theoretical calculations and models in order to resolve this problem.

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The mass of the top quark is measured in 36.3 of LHC proton-proton collision data collected with the CMS detector at . The measurement uses a sample of top quark pair candidate events containing one isolated electron or muon and at least four jets in the final state.

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