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1,255 results match your criteria: "National Centre for Scientific Research[Affiliation]"
Front Endocrinol (Lausanne)
December 2024
Société des Produits Nestlé S.A., Nestlé Institute of Health Sciences, Lausanne, Switzerland.
Background And Objective: Overweight and obesity affects millions of individuals worldwide and consequently represents a major public health concern. Individuals living with overweight and obesity have difficulty maintaining a low body weight due to known physiological mechanisms which prevent further weight loss and drive weight regain. In contrast, mechanisms which promote low body weight maintenance receive less attention and are largely unknown.
View Article and Find Full Text PDFAging Cell
December 2024
Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Athens, Greece.
Ultraviolet B (UVB) radiation is a major contributor to skin photoaging. Although mainly absorbed by the epidermis, UVB photons managing to penetrate the upper dermis affect human dermal fibroblasts (HDFs), leading, among others, to the accumulation of senescent cells. In vitro studies have shown that repeated exposures to subcytotoxic UVB radiation doses provoke HDFs' premature senescence shortly after the end of the treatment period.
View Article and Find Full Text PDFMaterials (Basel)
November 2024
Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research Demokritos, Patr. Gregoriou E & 27 Neapoleos Street, 15341 Agia Paraskevi, Greece.
This study explores the layer-by-layer (LBL) modification of polyacrylonitrile (PAN) hollow fibers for effective Mg/Li separation. It employs an LBL method of surface modification using polyelectrolytes, specifically aiming to enhance ion selectivity and improve the efficiency of lithium extraction from brines or lithium battery wastes, which is critical for battery recycling and other industrial applications. The modification process involves coating the hydrolyzed PAN fibers with alternating layers of positively charged polyelectrolytes, such as poly(allylamine hydrochloride) (PAH), polyethyleneimine (PEI), or poly(diallyldimethylammonium chloride) (PDADMAC) and negatively charged polyelectrolytes, such as poly(styrene sulfonate) (PSS), to form polyelectrolyte multilayers (PEMs).
View Article and Find Full Text PDFAnalyst
December 2024
Physics Department, Universitat Autònoma de Barcelona (UAB), 08193 Cerdanyola del Vallès, Barcelona, Spain.
Radioresistant tumours remain complex to manage with current radiotherapy (RT) techniques. Heavy ion beams were proposed for their treatment given their advantageous radiobiological properties. However, previous studies with patients resulted in serious adverse effects in the surrounding healthy tissues.
View Article and Find Full Text PDFRhinology
December 2024
Department of Otorhinolaryngology, CHU Hôtel Dieu, Nantes, France.
Background: Clinical trials have demonstrated the effectiveness of biologics in treating chronic rhinosinusitis with nasal polyps (CRSwNP). However, real-world evidence regarding patient outcomes and predictors of clinical response remains limited.
Methodology: In this multicentric 18-month follow-up study, 326 adult patients who initiated biologic therapy for severe uncontrolled CRSwNP were included.
Eur J Pain
January 2025
UCD School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
Background: Pain is the leading cause of disability and reduced quality of life worldwide. Despite the increasing burden for patients and healthcare systems, pain research remains underfunded and under focused. Having stakeholders identify and prioritize areas that need urgent attention in the field will help focus funding topics, reduce 'research waste', improve the effectiveness of pain research and therapy and promote the uptake of research evidence.
View Article and Find Full Text PDFPLoS One
December 2024
National Computing Infrastructure, Australian National University, Canberra, Australia.
Environmental challenges are rarely confined to national, disciplinary, or linguistic domains. Convergent solutions require international collaboration and equitable access to new technologies and practices. The ability of international, multidisciplinary and multilingual research teams to work effectively can be challenging.
View Article and Find Full Text PDFCureus
November 2024
First Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, GRC.
Int J Mol Sci
November 2024
Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Adipocytes derived from 3T3-L1 cells are a gold standard for analyses of adipogenesis processes and the metabolism of fat cells. A widely used histological and immunohistochemical staining and mass spectrometry lipidomics are mainly aimed for examining lipid droplets (LDs). Visualizing other cellular compartments contributing to the cellular machinery requires additional cell culturing for multiple labeling.
View Article and Find Full Text PDFJ Natl Cancer Inst
November 2024
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
bioRxiv
November 2024
Dept. of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA.
The RNA binding protein TIA1 is known to regulate stress responses. Here we show that TIA1 plays a much broader role in inflammatory cells, being required for the microglial sensome. We crossed TIA1 cKO mice (using a CX3CR1 driven cre element) to PS19 MAPT P301S tauopathy mice.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
November 2024
Laboratory of Clinical Microbiology, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Background: Studies link multidrug-resistant organism (MDRO) rectal colonization to increased infection risk, data from Greece, a country with high rates of MDRO, are limited.
Methods: We assessed bloodstream infection (BSI) risk following rectal colonization by MDROs across three Greek hospitals (2019-2022).
Results: Of 4,370 inpatients, 31.
Sci Rep
November 2024
School of Archaeology, University College Dublin (UCD), Belfield, Dublin 4, Ireland.
Front Pharmacol
October 2024
Department of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.
Sci Rep
November 2024
French National Centre for Scientific Research, Paris School of Economics, Paris, France.
When they are asked to test a given hypothesis, individuals tend to be biased towards confirming evidence. This phenomenon has been documented on different cognitive components: information search, weighing of evidence, and memory recall. However, the interpretation of these observations has been debated, and it remains unclear whether they truly reflect a confirmation bias (as opposed to e.
View Article and Find Full Text PDFEuro Surveill
November 2024
Clinical Microbiology Laboratory, "Attikon" University General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Pneumonia (Nathan)
November 2024
Department of Intensive Care Medicine, Lapeyronie University Hospital, University of Montpellier, 371 Avenue du Doyen Gaston Giraud, 34295, Montpellier, France.
Front Immunol
November 2024
Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.
Introduction: ER aminopeptidase 1 (ERAP1) is a polymorphic intracellular aminopeptidase with key roles in antigen presentation and adaptive immune responses. ERAP1 allotype 10 is highly protective toward developing some forms of autoimmunity and displays unusual functional properties, including very low activity versus some substrates.
Methods: To understand the molecular mechanisms that underlie the biology of allotype 10, we studied its enzymatic and biophysical properties focusing on its unique polymorphisms V349M and Q725R.
Phys Rev Lett
October 2024
CERN, Geneva, Switzerland.
A search for the exclusive hadronic decays W^{±}→π^{±}γ, W^{±}→K^{±}γ, and W^{±}→ρ^{±}γ is performed using up to 140 fb^{-1} of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of sqrt[s]=13 TeV. If observed, these rare processes would provide a unique test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders. Additionally, at future colliders, these decays could offer a new way to measure the W boson mass through fully reconstructed decay products.
View Article and Find Full Text PDFPhys Rev Lett
October 2024
CERN, Geneva, Switzerland.
J Biol Chem
October 2024
National Centre for Scientific Research "Demokritos", Institute of Biosciences and Applications, Athens, Greece. Electronic address:
Micromachines (Basel)
September 2024
Laboratoire Nanotechnologies Nanosystèmes, Institut Interdisciplinaire D'innovation Technologique, Université de Sherbrooke, 3000 Boulevard de l'Université, Sherbrooke, QC J1K 2R1, Canada.
This paper introduces a novel technology for the monolithic integration of GaN-based vertical and lateral devices. This approach is groundbreaking as it facilitates the drive of high-power GaN vertical switching devices through lateral GaN HEMTs with minimal losses and enhanced stability. A significant challenge in this technology is ensuring electrical isolation between the two types of devices.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Institute for Neuro-Immune Medicine-Clearwater, Clearwater, FL 33759, USA.
The European olive tree, L., and its polyphenols hold great therapeutic potential to treat neuroinflammation and cognitive impairment. This review examines the evidence for the anti-inflammatory and neuroprotective actions of olive polyphenols and their potential in the treatment of long COVID and neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS).
View Article and Find Full Text PDFAntioxidants (Basel)
October 2024
Institut de la Vision, French National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Sorbonne Université, 75012 Paris, France.
Blue light accelerates retinal aging. Previous studies have indicated that wavelengths between 400 and 455 nm are most harmful to aging retinal pigment epithelia (RPE). This study explored whether filtering these wavelengths can protect cells exposed to broad sunlight.
View Article and Find Full Text PDFJ Thromb Haemost
October 2024
National Institute of Health and Medical Research, National Research Institute for Agriculture, Food and Environment, Research Center for Cardiovascular and Nutrition, Faculty of Medicine, Aix Marseille University, Marseille, France; Reference Center on Constitutional Platelet Disorders, Biogenopole, University Hospital Center Timone, Public Assistance - Hospitals of Marseille, Marseille, France. Electronic address:
Background: Inherited platelet diseases are bleeding disorders characterized by either defects in platelet count or platelet function, the latter being less common and very heterogeneous. Numerous gene variants associated with abnormal receptors, granules, and signaling pathways have been reported. Despite significant advancements in our understanding, many patients still lack a precise diagnosis.
View Article and Find Full Text PDF