Modelling energy trilemma and economic growth on renewables in N11 economies: Do economic complexity matter?

Utilizing renewable energy is a necessity for accomplishing global agendas, including combating climate change and promoting sustainable development programs. Although much literature has investigated the nexus between energy sources and their affected regressors during the last few years, no appreciable emphasis is available in the previous studies respecting the influence of the energy trilemma index and economic expansion on the influence of the energy trilemma index and economic the renewables in N11 economies. Therefore, the current study analyzes the crucial influencing factors, including the energy trilemma, economic growth, economic complexity, financial development, and urban population, as drivers of renewable energy in N11 economics from 1990 to 2021 by utilizing a panel quantile regression approach.

1,2,3-Triazol-5-ylidene- 1,2,3-triazole-based tricarbonylrhenium(I) complexes: influence of a mesoionic carbene ligand on the electronic and biological properties.

The tricarbonylrhenium complexes that incorporate a mesoionic carbene ligand represent an emerging and promising class of molecules, the solid-state optical properties of which have rarely been investigated. The aim of this comprehensive study is to compare three of these complexes with their 1,2,3-triazole-based analogues. The Hirshfeld surface analysis of the crystallographic data revealed that the triazolylidene derivatives are more prone to π-π interactions than their 1,2,3-triazole-based counterparts.

Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity.

Recently, COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, caused > 6 million deaths. Symptoms included respiratory strain and complications, leading to severe pneumonia. SARS-CoV-2 attaches to the ACE-2 receptor of the host cell membrane to enter.

Experimental and density functional theory studies on some metal oxides and the derived nanoclusters: a comparative effects on human ferritin.

A comprehensive investigation into the green synthesis of metal oxide nanoparticles (NPs) has garnered significant attention due to its commendable reliability, sustainability, and environmentally friendly attributes. Green synthesis methods play a crucial role in mitigating the adverse effects associated with conventional approaches employed for nanostructure preparation. This research endeavors to examine the impact of ginger plant extract-assisted green synthesis of metal oxides NPs on the serum ferritin levels of anemic diabetic patients in vitro, focusing specifically on α-FeO and ZnO NPs.

A study on the effect of natural products against the transmission of B.1.1.529 Omicron.

Background: The recent outbreak of the Coronavirus pandemic resulted in a successful vaccination program launched by the World Health Organization. However, a large population is still unvaccinated, leading to the emergence of mutated strains like alpha, beta, delta, and B.1.

Assessing the role of green economy on sustainable development in developing countries.

Purpose: Over the last few years, the green economy (GE) notion has been realized as a key tool for achieving sustainable development (SD) in both developing and developed nations. Therefore, the current study tries to investigate the role of GE in achieving SD in developing countries. Through empirically examining the relationship between the GE and three different dependent variables which are GDP per capita, total unemployment rate, and poverty level, using cross-sectional data for 60 developing countries in 2018.

Covalent conjugates based on nanodiamonds with doxorubicin and a cytostatic drug from the group of 1,3,5-triazines: Synthesis, biocompatibility and biological activity.

We report the synthesis of covalent conjugates of nanodiamonds with doxorubicin and a cytostatic drug from the class of 1,3,5-triazines. The obtained conjugates were identified using a number of physicochemical methods (IR-spectroscopy, NMR-spectroscopy, XRD, XPS, TEM). As a result of our study, it was found that ND-СONH-Dox and ND-COO-Diox showed good hemocompatibility, since they did not affect plasma coagulation hemostasis, platelet functional activity, and erythrocyte membrane.

Modelling natural gas, renewables-sourced electricity, and ICT trade on economic growth and environment: evidence from top natural gas producers in Africa.

Addressing extensive global goals including growing energy-sourced electricity and advancing sustainable development plans strongly depends on natural gas as a transition fuel to renewable forms of energy. Therefore, by using pooled, random, and fixed-effects models, the current study investigates the effects of electricity sourced from natural gas (ENG), renewable energy (RE), and trade in information and communication technologies (ICTs) on economic growth and carbon dioxide (CO) emissions in Africa's top three natural gas producers, Algeria, Egypt, and Nigeria, from 1990 to 2020. The findings indicate that CO, ENG, ICT trade, and urbanization (UP) are all strongly and positively correlated to economic progress, with the exception of RE, which has an insignificant influence.

Insight into the role of clathrin-mediated endocytosis inhibitors in SARS-CoV-2 infection.

Emergence of SARS-CoV-2 variants warrants sustainable efforts to upgrade both the diagnostic and therapeutic protocols. Understanding the details of cellular and molecular basis of the virus-host cell interaction is essential for developing variant-independent therapeutic options. The internalization of SARS-CoV-2, into lung epithelial cells, is mediated by endocytosis, especially clathrin-mediated endocytosis (CME).

Assessing environmental concern and its association with carbon trade balances in N11 Do financial development and urban growth matter?

Expanding of complex global supply chains enhances the role of global trade in the deterioration of the environment by production redeployment across nations, which is tightly connected to emission transmission or the carbon trade balance. Although much earlier studies have assessed the link between emissions of carbon dioxide (CO) and their influenced variables in the past few years, no substantial attention is available in the literature review concerning the influence of carbon trade balance on the environment in N11 economies. Therefore, via economic progress, renewable/fossil energies consumption, financial development, and urbanization growth as control variables, the influence of the carbon trade balance on emissions of CO in N11 countries is explored from 1990 to 2020.

Antiureolytic activity of new water-soluble thiadiazole derivatives: Spectroscopic, DFT, and molecular docking studies.

Two new water-soluble thiadiazole compounds are prepared and characterized with various techniques. These compounds, 5-amino-1,3,4-thiadiazole hydrochloride (1) and 5-amino-3-(N-propane-2-imine)-1,3,4-thiadiazole chloride salt (2) were synthesized via Mannich reaction, and characterized by microelemental analysis, and some spectroscopic means (FTIR, UV-Vis, H NMR, C NMR and mass), in addition to single-crystal X-ray diffraction for compound 2. DFT calculations were conducted to study their geometry optimization, vibrational spectra, MEP maps, and NBO analysis.

Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility.

The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells.

Graphene Oxide of Extra High Oxidation: A Wafer for Loading Guest Molecules.

We present a new modification of graphene oxide with very high content (85 wt %) of oxygen-containing functional groups (hydroxy, epoxy, lactol, carboxyl, and carbonyl groups) that forms stable aqueous dispersion in up to 9 g·L concentration solutions. A novel faster method of the synthesis is described that produces up to 1 kg of the material and allows controlling the particle size in solution. The synthesized compound was characterized by various physicochemical methods and molecular dynamics modeling, revealing a unique structure in the form of a multilayered wafer of several sheets thick, where each sheet is highly corrugated.

Heteroleptic complexes of cocaine/TMEDA with some f block metals: Synthesis, DFT studies, spectral, thermal, cytotoxicity and antimetastatic properties.

A series of new three heteroleptic complexes of the general formula [Ln(Cn)(TMEDA)Cl(OH)]·2Cl·xHO, (where Ln = La(III), Er(III) and Yb(III), Cn = cocaine and TMEDA = N,N,N',N'-tetramethylethylenediamine) were synthesized, structurally characterized by elemental analysis, spectroscopic methods, molar conductivity and mass spectrometry. Thermal properties of the synthesized complexes and their kinetic thermodynamic parameters were studied. Theoretical calculations including geometry optimization, electronic structure and electronic and thermal energies were carried out using DFT and TD-DFT calculations at B3LYP/LANL2DZ level of theory and the different quantum chemical parameters were calculated.

Utility of 5-(furan-2-yl)-3-(-tolyl)-4,5-dihydro-1-pyrazole-1-carbothioamide in the synthesis of heterocyclic compounds with antimicrobial activity.

Background: Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores with a wide range of biological activities.

One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents.

Background: Thiazoles and pyridines are versatile synthetic scaffolds possessing wide spectrum of biological effects including potential antimicrobial activity.

Objective: In the efforts to develop suitable antimicrobia drugs, medicinal chemists have focused on thiazole derivatives. A novel series of 2-thiazolyl pyridines was prepared in a one-pot three-component reaction using 2-bromoacetyl pyridine as a starting precursor.

Melatonin charge transfer complex with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone: Molecular structure, DFT studies, thermal analyses, evaluation of biological activity and utility for determination of melatonin in pure and dosage forms.

A simple, accurate and fast spectrophotometric method for the quantitative determination of melatonin (ML) drug in its pure and pharmaceutical forms was developed based on the formation of its charge transfer complex with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as an electron acceptor. The different conditions for this method were optimized accurately. The Lambert-Beer's law was found to be valid over the concentration range of 4-100μgmL ML.

Synthesis and Antimicrobial Activity of Some New Thiadiazoles, Thioamides, 5-Arylazothiazoles and Pyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines.

A novel series of 1,3,4-thiadiazoles, 5-arylazothiazoles and hexahydropyrimido-[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines were synthesized via reaction of hydrazonoyl halides with each of alkyl carbothioates, carbothioamides and 7-thioxo-5,6,7,8-tetrahydropyrimido-[4,5-d]pyrimidine-2,4(1H,3H)-diones in the presence of triethylamine. The structures of the newly synthesized compounds were established based on their spectral data, elemental analyses and alternative synthetic routes whenever possible. Also, the newly synthesized compounds were screened for their antimicrobial activity against various microorganisms.

Alterations of immune functions in heroin addicts.

The alteration of peripheral blood T-and B-lymphocyte proliferative responses were determined during different periods of withdrawal in heroin (Hw) and heroin / bhang (HBw) addicts. The results clearly demonstrated a significant decrease in the response of T- lymphocytes to PHA-stimulation and secretion of IL-2 in both Hw and HBw addicts. The in vitro presence of naloxone induced further inhibition of the PHA proliferative response and IL-2 production.

A molecular approach to the study of structure-activity correlation for some amphetamines.

Drug activity depends on both the fine as well as the gross structure of the molecule. In this work, the properties of the molecule that are dependent on its fine structure such as: dipole moment, ionization potential and energies of the HOMO and LUMO were calculated for the optimized geometry of some drugs using Ab initio method and the GAMESS program. At physiological pH, the amine part of the drug would be partially protonated, the calculations were carried out on both the charged and the free base forms.