139 results match your criteria: "National Center for PTSD at VA Boston Healthcare System[Affiliation]"
J Clin Psychol
December 2024
National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts, USA.
Objective: To assess, by interview, the rates of eating disorders in a nationally representative sample of recent veterans, describe their DSM-5 eating disorder diagnoses and the occurrence of comorbid psychiatric disorders. To conduct an exploratory case-control analysis of previously documented and additional specific military risk factors before eating disorder onset to inform studies of prospective risk.
Method: Using a two-stage design, probable cases and controls were identified by screening questionnaires from a sample of 1494 veterans who completed a survey study and interviewed to establish case status and confirm probable co-morbid psychiatric diagnoses.
Traumatology (Tallahass Fla)
September 2024
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University.
Trauma exposure and drinking motives (e.g., social, enhancement, coping) are both associated with increased alcohol use and related problems.
View Article and Find Full Text PDFAlthough there are effective psychotherapies available for posttraumatic stress disorder (PTSD), brief treatments for PTSD are needed to expand the reach of treatment. Written exposure therapy (WET) is a brief treatment that has the potential to fill an important need in PTSD treatment and has a rapidly expanding evidence base to support its use. In this paper we provide information on how WET was developed, and we present proposed underlying mechanisms of the treatment and evidence supporting the underlying mechanism.
View Article and Find Full Text PDFBrain Behav Immun
January 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research, Boston Institute of MIT and Harvard, Cambridge, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Boston MA, USA.
Posttraumatic stress disorder (PTSD) is associated with mortality and increased risk of diseases of aging, but underlying mechanisms remain unclear. We examine associations of PTSD with one potential pathway, accelerated epigenetic aging. In a longitudinal cohort of trauma-exposed middle-aged women (n = 831, n observations = 1,516), we examined cross-sectional and longitudinal associations between PTSD, with and without comorbid depression, and epigenetic aging measured by six clocks at two time points approximately 13.
View Article and Find Full Text PDFBrain Imaging Behav
September 2024
Translational Research Center for TBI and Stress Disorders (TRACTS 182-JP), VA Boston Healthcare System, 150 S. Huntington Avenue, Boston, MA, 02130, USA.
Metabolic syndrome is a collection of health factors that increases risk for cardiovascular disease. A condition of aging, metabolic syndrome is associated with reduced brain network integrity, including functional connectivity alterations among the default mode, regions vulnerable to neurodegeneration. Prevalence of metabolic syndrome is elevated in younger populations including post-9/11 Veterans and individuals with posttraumatic stress disorder, but it is unclear whether metabolic syndrome affects brain function in earlier adulthood.
View Article and Find Full Text PDFJ Clin Psychol
December 2024
National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts, USA.
Objective: Trauma exposure, particularly interpersonal trauma, is prevalent among individuals with eating disorders (EDs), and trauma exposure and the subsequent development of posttraumatic stress disorder have been associated with poorer outcomes for ED treatment. To our knowledge, there are no published investigations of trauma exposure among individuals with avoidant/restrictive food intake disorder (ARFID), a new diagnosis introduced by the Diagnostic and Statistical Manual of Mental Disorders-5. We investigated associations between trauma exposure and ARFID profiles in a sample of U.
View Article and Find Full Text PDFJ Trauma Stress
October 2024
Department of Psychiatry, Leiden University, Leiden, the Netherlands.
JAMA Netw Open
July 2024
Epidemiology Department, University of Nebraska Medical Center College of Public Health, Omaha.
Importance: Disasters experienced by an entire community provide opportunities to understand individual differences in risk for adverse health outcomes over time. DNA methylation (DNAm) differences may help to distinguish individuals at increased risk following large-scale disasters.
Objective: To examine the association of epigenetic age acceleration with probable posttraumatic stress disorder (PTSD) and PTSD symptom severity in women.
Focus (Am Psychiatr Publ)
July 2024
Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA (Huckins, Signer, Johnson); Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA (Huckins, Signer); Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mental Illness Research, Education and Clinical Centers, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY 14068, USA (Huckins); School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA (Wu); Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA (Wu, Bulik); National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA; Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA (Mitchell); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA (Bulik).
Substantial progress has been made in the understanding of anorexia nervosa (AN) and eating disorder (ED) genetics through the efforts of large-scale collaborative consortia, yielding the first genome-wide significant loci, AN-associated genes, and insights into metabo-psychiatric underpinnings of the disorders. However, the translatability, generalizability, and reach of these insights are hampered by an overly narrow focus in our research. In particular, stereotypes, myths, assumptions and misconceptions have resulted in incomplete or incorrect understandings of ED presentations and trajectories, and exclusion of certain patient groups from our studies.
View Article and Find Full Text PDFSexual orientation and gender identity/expression change efforts (SOGIECEs) are discredited practices that are associated with serious negative effects and incompatible with modern standards for clinical practice. Despite evidence linking SOGIECEs with serious iatrogenic effects, and despite support for LGBTQ+-affirmative care alternatives, SOGIECE practices persist. In the 1970s and 1980s, Behavior Therapy published articles testing and/or endorsing SOGIECEs, thereby contributing to their overall development, acceptance, and use.
View Article and Find Full Text PDFJ Affect Disord
September 2024
Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada; Department of Medicine, McGill University, Montréal, Québec, Canada; Department of Psychiatry, McGill University, Montréal, Québec, Canada; Department of Psychology, McGill University, Montréal, Québec, Canada; Biomedical Ethics Unit, McGill University, Montréal, Québec, Canada.
Eur J Psychotraumatol
June 2024
Department of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, USA.
Symptom accommodation by family members (FMs) of individuals with posttraumatic stress disorder (PTSD) includes FMs' participation in patients' avoidance/safety behaviours and constraining self-expression to minimise conflict, potentially maintaining patients' symptoms. The Significant Others' Responses to Trauma Scale (SORTS) is the only existing measure of accommodation in PTSD but has not been rigorously psychometrically tested. We aimed to conduct further psychometric analyses to determine the factor structure and overall performance of the SORTS.
View Article and Find Full Text PDFJ Trauma Stress
December 2024
Department of Psychology, Binghamton University, Binghamton, New York, USA.
Individuals with posttraumatic stress symptoms (PTSS) often consume alcohol to manage PTSS-related discomfort, which can negatively impact individual and interpersonal functioning. Processes including emotion regulation and dyadic coping may influence the effects of PTSS and drinking patterns on relationship functioning. The present study examined how PTSS and risky drinking may function through the associations between maladaptive individual and interpersonal coping strategies and relationship distress among trauma-exposed individuals.
View Article and Find Full Text PDFAnxiety Stress Coping
May 2024
Women's Health Sciences Division, National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA.
Background: Posttraumatic stress disorder (PTSD) and sleep disturbance are highly comorbid and repetitive negative thinking (RNT) is associated with both sleep disturbance and PTSD. However, few studies have examined the association between RNT and sleep disturbance in individuals exposed to trauma, with and without PTSD.
Method: Associations between trait-level and trauma-related RNT, insomnia, and sleep quality were investigated in a trauma-exposed MTurk ( = 342) sample.
J Trauma Stress
April 2024
National Center for PTSD at VA Boston Healthcare System & Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
J Trauma Stress
February 2024
National Center for PTSD, Executive Division, White River Junction, Vermont, USA.
Posttraumatic stress disorder (PTSD) Criterion A, also known as the "stressor criterion," has been a major source of debate ever since PTSD was added to the third edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM) in 1980. Since then, the traumatic stress field has held an ongoing debate about how to best define Criterion A and the events that it covers. Because of the COVID-19 pandemic and recent race-based incidents, the Criterion A debate has been reinvigorated.
View Article and Find Full Text PDFFront Psychiatry
November 2023
Department of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN, United States.
Introduction: This clinical trial aimed to determine the influence of attention-deficit/hyperactivity disorder (ADHD) on neuro-ophthalmologic function and brain-derived blood biomarkers following acute subconcussive head impacts.
Methods: The present trial consisted of age- and sex-matched samples with a ratio of 1:1 between two groups with a total sample size of 60 adults (age ± SD; 20.0 ± 1.
Brain Behav Immun
January 2024
National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA; Boston University Chobanian & Avedisian School of Medicine, Department of Psychiatry, Boston, MA, USA; Boston University School of Public Health, Department of Biostatistics, Boston, MA, USA; Boston University School of Medicine, Department of Medicine, Biomedical Genetics, Boston, MA, USA.
Traumatic stress is associated with both accelerated epigenetic age and increased risk for dementia. Accelerated epigenetic age might link symptoms of traumatic stress to dementia-associated biomarkers, such as amyloid-beta (Aβ) proteins, neurofilament light (NFL), and inflammatory molecules. We tested this hypothesis using longitudinal data obtained from 214 trauma-exposed military veterans (85 % male, mean age at baseline: 53 years, 75 % White) who were assessed twice over the course of an average of 5.
View Article and Find Full Text PDFJ Mood Anxiety Disord
October 2023
National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA.
Advanced epigenetic age is associated with psychopathology and may help to explain the link between psychopathology and physical health morbidity and mortality. Using a longitudinal sample of 171 trauma-exposed Veterans, we modeled the rate of change in epigenetic age across two time points (averaging 5.58 years apart) using two epigenetic age algorithms (GrimAge and Horvath) and tested associations with posttraumatic stress disorder (PTSD), alcohol use disorder (AUD), and depression.
View Article and Find Full Text PDFEat Behav
December 2023
National Center for PTSD at VA Boston Healthcare System, United States of America; Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, United States of America. Electronic address:
Objective: Weight discrimination, defined as mistreatment of people based on body weight, is associated with body image concerns and eating disorder (ED) symptoms. Military veterans are particularly vulnerable to developing ED symptoms, which may be due to experiences of weight discrimination resulting from the military's strict weight and fitness requirements. However, no previous study has examined these associations among veterans.
View Article and Find Full Text PDFJ Clin Psychol Med Settings
March 2024
National Center for PTSD at VA Boston Healthcare System, Boston, USA.
Chronic pain is a debilitating condition for many military Veterans and is associated with posttraumatic stress disorder (PTSD). This study examined the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) in 144 Veterans (88.2% male, mean age = 57.
View Article and Find Full Text PDFJ Trauma Stress
August 2023
Department of Psychiatry and Behavioral Sciences, Duke Health, Durham, North Carolina, USA.
Insomnia and nightmares are common in patients with posttraumatic stress disorder (PTSD). They are associated with worse psychological and physical health and worse PTSD treatment outcomes. In addition, they are resistant to PTSD treatments, which do not typically address sleep disorders.
View Article and Find Full Text PDFIntimate partner violence (IPV) is a major public health concern, leading to prevention efforts focused on identifying risk indicators of escalating conflict between partners. Certain behaviors during conflict discussions have been uniquely linked to IPV, and there is evidence that disengagement behaviors-an emerging construct-are associated with IPV as well. However, research on disengagement and IPV has largely been limited to self-report, and available observational research is largely cross-sectional.
View Article and Find Full Text PDFJ Clin Sleep Med
August 2023
Department of Psychiatry and Behavioral Sciences, Duke Health, Durham, North Carolina.
Study Objectives: Sleep disturbances are common in military personnel with posttraumatic stress disorder (PTSD) and may persist following treatment. This study examined service members seeking treatment for PTSD, reporting insomnia symptoms, nightmares, excessive daytime sleepiness, and potential obstructive sleep apnea at baseline and the impact of sleep disturbances on a course of PTSD treatment.
Methods: In this secondary analysis, sleep was evaluated in 223 service members who participated in a randomized clinical trial comparing Cognitive Processing Therapy for PTSD delivered in individual or group formats.