214 results match your criteria: "National Center for Biotechnology Information NCBI[Affiliation]"

BERT-GT: cross-sentence n-ary relation extraction with BERT and Graph Transformer.

Bioinformatics

April 2021

National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, MD 20894, USA.

Motivation: A biomedical relation statement is commonly expressed in multiple sentences and consists of many concepts, including gene, disease, chemical and mutation. To automatically extract information from biomedical literature, existing biomedical text-mining approaches typically formulate the problem as a cross-sentence n-ary relation-extraction task that detects relations among n entities across multiple sentences, and use either a graph neural network (GNN) with long short-term memory (LSTM) or an attention mechanism. Recently, Transformer has been shown to outperform LSTM on many natural language processing (NLP) tasks.

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The Missing Tailed Phages: Prediction of Small Capsid Candidates.

Microorganisms

December 2020

Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.

Tailed phages are the most abundant and diverse group of viruses on the planet. Yet, the smallest tailed phages display relatively complex capsids and large genomes compared to other viruses. The lack of tailed phages forming the common icosahedral capsid architectures T = 1 and T = 3 is puzzling.

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LitCovid: an open database of COVID-19 literature.

Nucleic Acids Res

January 2021

National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

Since the outbreak of the current pandemic in 2020, there has been a rapid growth of published articles on COVID-19 and SARS-CoV-2, with about 10,000 new articles added each month. This is causing an increasingly serious information overload, making it difficult for scientists, healthcare professionals and the general public to remain up to date on the latest SARS-CoV-2 and COVID-19 research. Hence, we developed LitCovid (https://www.

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Article Synopsis
  • SARS-CoV-2 is a new virus causing COVID-19, part of the Coronaviridae family with studied biology.
  • Recently developed bioinformatics tools aim for quick detection and analysis of the virus to aid in controlling the pandemic.
  • The review details various bioinformatics tools for routine infection detection, sequencing data analysis, tracking COVID-19, studying virus evolution, and finding drug targets, all accessible for free online.
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Predicting risk of late age-related macular degeneration using deep learning.

NPJ Digit Med

August 2020

National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, MD USA.

By 2040, age-related macular degeneration (AMD) will affect ~288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the sight-threatening stage, is critical for clinical actions, including medical interventions and timely monitoring. Although deep learning has shown promise in diagnosing/screening AMD using color fundus photographs, it remains difficult to predict individuals' risks of late AMD accurately.

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Ten tips for a text-mining-ready article: How to improve automated discoverability and interpretability.

PLoS Biol

June 2020

National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.

Article Synopsis
  • Data-driven biomedical research relies on structured, computable data increasingly generated through automated text mining tools, which have improved significantly.
  • The authors present 10 writing tips and introduce the web tool PubReCheck to assist authors in overcoming common challenges that hinder text-mining effectiveness.
  • By following these guidelines, authors can enhance the visibility and impact of their work, benefiting both themselves and their audience.
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Recent advances in biomedical literature mining.

Brief Bioinform

May 2021

Department of Healthcare Policy and Research, Weill Medical College of Cornell University, New York, NY 10065, USA.

The recent years have witnessed a rapid increase in the number of scientific articles in biomedical domain. These literature are mostly available and readily accessible in electronic format. The domain knowledge hidden in them is critical for biomedical research and applications, which makes biomedical literature mining (BLM) techniques highly demanding.

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