[A successful case of surgical treatment for the bronchogastric tube fistula originated in the reconstructed gastric tube after operation for esophageal cancer].

A successful case of surgical treatment for a bronchogastric tube fistula after resection for esophageal cancer are reported herein. The patient was a 67-year-old male who had undergone blunt total esophagectomy with reconstruction of a whole gastric tube pulled up through the posterior mediastinum and laryngopharyngectomy with a permanent end-tracheostomy in February, 1983. After the operation, he was irradiated prophylactically to the both neck and upper mediastinum with a total dose of 50 Gy.

[Prognostic factors and risk groupings in multiple myeloma].

The survival duration of patients with multiple myeloma (MM) ranges from a few months to more than 10 years. Numerous studies have been undertaken to determine which factors may influence the patients' prognosis. The identification of these prognostic factors is important both for stnatification of patients and evaluation of therapy.

A randomized cross-over study of high-dose metoclopramide plus dexamethasone versus granisetron plus dexamethasone in patients receiving chemotherapy with high-dose cisplatin.

We carried out a randomized, single-blind, cross-over trial to compare the antiemetic effect, for both acute and delayed emesis, of granisetron plus dexamethasone (GRN+Dx) with that of high-dose metoclopramide plus dexamethasone (HDMP+Dx). Fifty-four patients with primary or metastatic lung cancer, given single-dose cisplatin (> 80 mg/m2) chemotherapy more than twice, were enrolled in this study. They were treated with both HDMP+Dx and GRN+Dx in two consecutive chemotherapy courses.

[Microtubules and antineoplastic drugs].

Microtubules, which are composed of polymerized tubulin dimers, play an important role in various cell functions. For example, they maintain cell shape, form mitotic spindles in M phase of cell cycle, and carry an axonal transport in nerve cells. Microtubules have also been an important target of cancer chemotherapy.

[Coronet status of digital radiography in chest medicine].

It has been ten years since Computed Radiography (CR) was introduced to evaluate its efficacy on the diagnosis of chest diseases in Japan. Over 600 CR systems are in their daily clinical use. CR images improve the quality of chest X-ray diagnosis with its enhancement parameters, that is, the digital image's contrast and edge enhancement.