416 results match your criteria: "Nasolacrimal Duct Congenital Anomalies"
The effect of age on congenital nasolacrimal duct obstruction probing and stent intubation outcomes in pediatric Down syndrome patients.
J AAPOS
October 2024
Case Western Reserve University School of Medicine, Cleveland, Ohio; Department of Ophthalmology, University Hospitals Cleveland Medical Center, Cleveland, Ohio. Electronic address:
Article Synopsis
- The study aimed to evaluate how the age at which patients with Down syndrome underwent treatment for congenital nasolacrimal duct obstruction (CNLDO) affected their symptom improvement and need for additional surgery.
- Medical records of 49 patients treated between 2012 and 2021 were analyzed, categorizing them based on whether they were younger or older than 3 years at the time of the first stent placement.
- Results indicated that there were no significant differences in symptom resolution or reoperation rates based on age, suggesting that older patients might still benefit from the intervention.
Duplication of the Lacrimal Sac With Three Canaliculi.
Ophthalmic Plast Reconstr Surg
September 2024
Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad-34, India.
Article Synopsis
- * Duplication of body structures is rare and has been documented in several organs, but duplication of the lacrimal sac is not previously reported.
- * This case highlights a specific instance of nasolacrimal duct obstruction accompanied by duplication of the lacrimal sac and the presence of three canaliculi.
Congenital nasolacrimal duct obstruction: clinical guideline.
Jpn J Ophthalmol
July 2024
Eye Center, Shinseikai Toyama Hospital, Imizu, Japan.
Congenital ocular and its adnexal anomalies among Indian pediatric age groups.
Bioinformation
April 2024
Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.
Article Synopsis
- - The study, conducted over two years at RL Jalappa Hospital in Karnataka, India, examined the causes of eye problems in children aged 0-12, revealing that 57% of the 56 patients were male and a significant number had a family history of eye issues.
- - A high percentage of the children's parents were in consanguineous marriages, with 41% in second-degree and 59% in third-degree relationships, contributing to the congenital eye conditions observed.
- - The research identified nasolacrimal duct anomalies as the most common eye issue (32%), suggesting that increased education and counseling on the risks of consanguinity and other factors during pregnancy could help prevent ocular morbidity in children.
A case report of proboscis lateralis: emphasis on the reconstruction of the lacrimal drainage system.
Transl Pediatr
May 2024
Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery, Beijing, China.
Article Synopsis
- Proboscis lateralis (PL) is a rare craniofacial congenital malformation, with a classification system developed in 1985 that highlights its associated anomalies, notably sinonasal deformities and ocular issues.
- A case study of a 20-month-old girl with PL revealed complications after initial surgery, leading to the need for a second procedure to reconstruct the lacrimal drainage system, which was successfully performed with a multidisciplinary team.
- This case emphasizes the importance of comprehensive treatment plans for PL that take into account associated ocular anomalies and ensure proper lacrimal drainage reconstruction.
Endoscopy changing the treatment of congenital nasolacrimal duct obstruction.
Arq Bras Oftalmol
May 2024
Departamento de Oftalmologia e Otorrinolaringologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Incidence and clinical characteristics of congenital nasolacrimal duct obstruction with concurrent craniofacial abnormalities among a population-based cohort.
Orbit
October 2024
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Article Synopsis
- This study investigates the incidence and outcomes of congenital nasolacrimal duct obstruction (CNLDO) in infants with craniofacial abnormalities, finding a 2.05% occurrence among CNLDO patients in a specific US county over a decade.
- It reports that infants with craniofacial conditions are diagnosed later and require surgical probing more frequently than those without abnormalities (31.7% vs 14.5%, respectively).
- The study suggests that while many cases of CNLDO resolve on their own by age one, closer monitoring and potential surgical intervention may be necessary for those with craniofacial abnormalities.
Bilateral Dacryocystoceles in Congenital Arhinia.
Ophthalmic Plast Reconstr Surg
November 2024
Ophthalmic Plastic Surgery Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, U.S.A.
Article Synopsis
Lacrimal Obstruction in Craniosynostosis: Anatomical and Genetic Risk Factors.
Ophthalmic Plast Reconstr Surg
September 2024
Division of Ophthalmology, Children's Hospital of Philadelphia.
Article Synopsis
- The study aimed to determine if children with craniosynostosis have higher rates of nasolacrimal duct obstruction (NLDO) and to identify potential risk factors.
- A retrospective review was conducted on 767 craniosynostosis patients over 11 years, finding that NLDO occurred in 6.2% of participants, with higher rates in those with genetic or syndromic associations.
- The findings suggest that NLDO is more prevalent in this population compared to the general public, particularly among females and patients with certain genetic variants, highlighting the need for ophthalmic evaluations in craniosynostosis patients.
Unlocking the secrets of success in probing for congenital nasolacrimal duct obstruction: investigating the factors that matter.
Int Ophthalmol
May 2024
Department of Ophthalmology, Hisar Hospital Intercontinental, Istanbul, Turkey.
Article Synopsis
- The study aimed to evaluate how various factors affect the success rates of probing for congenital nasolacrimal duct obstruction (CNLDO) in children.
- A total of 239 eyes from 202 patients were analyzed, categorized by age groups and types of obstruction, with 86.61% overall success found after a follow-up period.
- Results showed that success rates were higher for membranous obstruction (MO) compared to incomplete complex obstruction (ICO), particularly declining for ICO in patients over 36 months old.
Dilemmas in the management of lacrimal drainage anomalies in BOSMA (congenital arhinia-microphthalmia) syndrome.
Orbit
May 2024
Govindram Seksaria Institute of Dacryology, LV Prasad Eye Institute, Hyderabad, India.
Article Synopsis
- - Congenital arhinia-microphthalmos syndrome, or BOSMA syndrome, is a rare condition marked by the complete lack of one or both nasal cavities, along with various facial and eye-related abnormalities.
- - The absence of the nasolacrimal duct leads to issues with tear drainage, manifesting as dilated lacrimal sacs or mucoceles.
- - A team of specialists from several fields, including genetics and surgery, should collaborate early in treatment to ensure comprehensive care for affected individuals.
The incidence of pediatric dacryocystitis among a population-based cohort of infants with congenital nasolacrimal duct obstruction.
J AAPOS
June 2024
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. Electronic address:
Article Synopsis
Ophthalmic features of Lamb-Shaffer syndrome: a case series.
J AAPOS
June 2024
Northwell, New Hyde Park, New York; Cohen Children's Medical Center, Queens, New York.
Article Synopsis
- Lamb-Shaffer syndrome (LSS) is a rare genetic neurodevelopmental disorder affecting fewer than 100 people globally, specifically characterized by diverse ophthalmic issues.
- In a study of 6 pediatric patients with LSS, strabismus was found in 5, with exotropia being the most common type, and all patients exhibited significant refractive errors, particularly astigmatism.
- Notable eye-related complications included various optic nerve abnormalities, such as pallor and hypoplasia, along with other issues like ptosis and nystagmus in some patients.
Ocular manifestations of CHARGE syndrome in a pediatric cohort with genotype/phenotype analysis.
Am J Med Genet A
August 2024
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Article Synopsis
- The research included a review of 42 patients' medical charts, revealing that 93% exhibited eye problems, with issues like optic nerve/chorioretinal colobomas being the most common.
- The study noted variability in eye conditions with no clear link to specific genetic variants, highlighting the need for more research to understand these associations better.
A Family with EEC Syndrome in the Son and ADULT Syndrome in His Father Caused by the c.797G>A (p.Arg266Gln) Pathogenic Variant in the Gene.
Mol Syndromol
February 2024
Center for Registry and Research in Congenital Anomalies (CRIAC), Service of Genetics and Cytogenetic Unit, Pediatric Division, Dr. Juan I. Menchaca Civil Hospital of Guadalajara, Guadalajara, Mexico.
Article Synopsis
Reconstruction of an Eyelid Defect Associated with Congenital Coloboma in a 7-Month-Old Male Infant Using an Acellular Dermal Allograft.
Am J Case Rep
February 2024
Department of Ophthalmology, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing, China (mainland).
Article Synopsis
- Congenital eyelid coloboma in children can lead to various complications like keratitis and amblyopia, particularly when over half of the eyelid margin is affected, making repairs difficult.
- A case involving a 7-month-old boy with significant eyelid defects was treated using an Acellular Dermal Allograft (ADA), involving multiple surgical procedures including drainage tube insertion and eyelid reconstruction.
- While the initial results of using ADA were positive, with good postoperative eyelid shape, there is a concern about the gradual appearance of lower eyelid retraction, indicating a need for further research on surgical techniques.
Anisometropia and Amblyopia Outcomes in Early Versus Late Resolution of Congenital Nasolacrimal Duct Obstruction in Older Infants.
Ophthalmic Plast Reconstr Surg
January 2024
Department of Ophthalmology, University of Washington, Seattle, Washington, U.S.A.
Article Synopsis
Efficacy of Lacrimal Sac Massage in Management of Congenital Nasolacrimal Duct Obstruction in Infants: An Observational Study of 853 Cases from a Single Institute of Eastern Asia.
Middle East Afr J Ophthalmol
January 2024
Department of Pathology, Dr. B. C. Roy Post Graduate Institute of Paediatric Sciences, Kolkata, West Bengal, India.
Article Synopsis
- CNLDO is the most common cause of excessive tearing (epiphora) in infants, typically resolving spontaneously by age 1 in 80-90% of cases.
- A study conducted over 5 years involved infants diagnosed with CNLDO, treated with lacrimal sac massage, and evaluated for improvement monthly.
- Results showed that 86.75% of infants improved after 3 months of massage, suggesting that conservative management is the best treatment approach for CNLDO up to 12 months of age.
Bony Congenital Nasolacrimal Duct Obstruction: A Novel Phenotype of Aplasia of Lacrimal and Major Salivary Glands.
Ophthalmology
May 2024
Department of Ophthalmology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China; Department of Ophthalmology, Baoding Children's Hospital, Hebei Province, China. Electronic address:
Article Synopsis
- Aplasia of lacrimal and salivary glands (ALSG) is a condition where key glands (tear and saliva producers) are underdeveloped, causing issues like dry eyes and blockages in tear drainage.
- This study focused on three Chinese families affected by a specific type of blockage called bony congenital nasolacrimal duct obstruction (CNLDO) to understand if genetic mutations are linked to this condition.
- Clinical evaluations, imaging tests, and whole exome sequencing revealed a correlation between ALSG and specific mutations in the Fgf10 gene, confirming the ALSG diagnosis in affected patients.
Assessing the success rate of treatment in simple and complex congenital nasolacrimal duct obstruction: a systematic review and meta-analysis.
Graefes Arch Clin Exp Ophthalmol
July 2024
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- The study aimed to assess and compare the success rates of probing and intubation in patients with congenital nasolacrimal duct obstruction (CNLDO) through a review of 21 relevant studies.
- It found that the success rate (SR) for treatment was 88% in simple CNLDO and 57% in complex CNLDO, with intubation significantly improving SR in complex cases.
- The conclusion emphasized that while intubation doesn't offer much advantage for simple CNLDO, it should be prioritized for complex CNLDO, and delaying treatment can benefit complex cases but not simple ones.
Evaluation of nasolacrimal canal morphology in different facial skeletal relationships.
J Stomatol Oral Maxillofac Surg
June 2024
Department of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu 600095, India.
Article Synopsis
- Abnormal variations in the nasolacrimal canal (NLC) can lead to surgical injuries and complications during craniomaxillofacial procedures, such as nasolacrimal obstruction and epiphora.
- This study aimed to analyze the size and volume of the NLC across different facial skeletal types to improve surgical accuracy and safety.
- Results showed significant volume differences in the NLC between Class I and UCLP groups, with UCLP having the largest volume, but no significant differences based on facial side or skeletal base configuration.
Re: "Outcome of Primary Monocanalicular Stent Placement in Pediatric Down Syndrome Patients with Congenital Nasolacrimal Obstruction".
Ophthalmic Plast Reconstr Surg
November 2023
Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Science, Tehran, Iran.