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Acceptability and efficacy of a gel hypotonic oral rehydration solution in children with acute gastroenteritis.

Eur J Gastroenterol Hepatol

May 2015

aNeonatology Unit, AORN dei Colli - V. Monaldi Hospital bDepartment of Translational Medical Science - Pediatric Section cEuropean Laboratory for the Investigation of Food Induced Diseases, University of Naples 'Federico II', Naples dDepartment of Gynaecology-Obstetrics and Perinatal Medicine University of Rome 'La Sapienza', Rome, Italy.

Objective: Oral rehydration solution remains the mainstay of acute gastroenteritis therapy. The aim of this study was to investigate the acceptability of a new zinc-containing hypotonic super-oral rehydration solution (ORS) in a gel formulation and its efficacy in reducing the duration and severity of diarrhea in children.

Methods: This was a randomized-controlled trial of children (5-36 months of age) observed for diarrhea lasting less than 24 h.

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