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LINC01518 predicts poor prognosis of prostate cancer and promotes its progression by regulating hsa-miR-320a/CNKSR2 axis.

Discov Oncol

October 2024

The Science and Education Department, Nantong Rici Hospital, Nantong Rici Hospital Affiliated to Yangzhou University, No. 2000, Xinghu Avenue, Economic and Technological Development Zone, Nantong, 226000, China.

Article Synopsis
  • * This study investigates the role of a long non-coding RNA called LINC01518 in PCa, finding that it is overexpressed in cancer cells and correlates with poor patient prognosis.
  • * LINC01518 promotes the expression of CNKSR2 by binding to hsa-miR-320a. When LINC01518 is knocked down, PCa cell growth is inhibited, suggesting its potential as a therapeutic target.
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