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Supramolecular interaction in the action of drug delivery systems.

Chem Sci

May 2024

College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University Tianjin 300071 China

Article Synopsis
  • - The text argues that current drug delivery systems (DDSs) are not performing optimally for complex diseases and highlights the critical role of supramolecular interactions in improving various aspects like biocompatibility and drug stability.
  • - It points out that while there is some existing knowledge about these interactions, they are often neglected during the design of DDSs, particularly in clinically used systems like liposomes and polymers.
  • - The aim is to encourage more attention on supramolecular interactions to enhance DDS development, emphasizing their importance in connecting DDSs with biological systems.
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